Virus-like particle secretion and genotype-dependent immunogenicity of dengue virus serotype 2 DNA vaccine [PDF]
, 2014 Dengue virus (DENV), composed of four distinct serotypes, is the most important and rapidly emerging arthropod-borne pathogen and imposes substantial economic and public health burdens.
Chang, Gwong-Jen J +4 more
core +1 more source
DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications
Advanced Materials, EarlyView.DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding +5 more
wiley +1 more source
Universal Prophylactic Antitumor Vaccination Using Stem Cell Membrane‐Coated Nanoparticles
Advanced Materials, EarlyView.Induced pluripotent stem cell membrane is coated onto adjuvant‐loaded nanoparticle cores to create a universal cancer vaccine. The formulation utilizes oncofetal antigens present on the cell membrane to elicit broadly protective immune responses in vivo.
Nishta Krishnan +10 more
wiley +1 more source
Journal of Biological Engineering, 2019 Background Influenza viruses cause hundreds of thousands of respiratory diseases worldwide each year, and vaccination is considered the most effective approach for preventing influenza annual epidemics or pandemics.
Chia-Chun Lai +7 more
doaj +1 more source
Journal of Infectious Diseases, 2014 BACKGROUND Noroviruses are the most important viral causes of gastroenteritis-related morbidity and mortality. A randomized, double-blind, placebo-controlled study evaluated an adjuvanted bivalent intramuscular norovirus virus-like particle (VLP) vaccine.
J. Treanor +9 more
semanticscholar +1 more source
Studies on processing, particle formation, and immunogenicity of the HIV-1 gag gene product: a possible component of a HIV vaccine [PDF]
, 1992 Antigens in a particulate conformation were shown to be highly immunogenic in mammals. For this reason, the particle forming capacity of derivatives of the HIV-1 group specific core antigen p55 gag was assayed and compared dependent on various expression
Deby, G. +7 more
core +1 more source
AN ELECTRON MICROSCOPE STUDY OF THE MORPHOLOGY AND DISTRIBUTION OF THE INTRACYTOPLASMIC "VIRUS-LIKE" PARTICLES OF EHRLICH ASCITES TUMOR CELLS [PDF]
, 1957 W. Robert Adams, Alfred M. Prince
openalex +1 more source
Improving global human health through norovirus virus-like particle manufacturing [PDF]
, 2016 Norovirus infection is the most common cause of acute gastroenteritis in the U.S., estimated to afflict 21 million people per year. For scale-up manufacturing of a norovirus vaccine candidate, the baculovirus expression system has been used in 1000 L ...
Shepard, Scot
core +1 more source
Virus-Like Particles and Cytopathic Activity in Urine of Patients with Leukemia [PDF]
, 1966 Richard P. Ames +3 more
openalex +1 more source
Advanced Materials Interfaces, EarlyView.The formation of stable clusters of gold nanoparticles with oligonucleotides at different solution conditions is explored. DNA base homogeneity and strand directionality influence the binding with gold nanoparticles leading to interesting clustering behavior that can be relevant for SERS applications.
Shaila Thakur +3 more
wiley +1 more source