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H3N2 canine influenza virus-like particle vaccine with great protection in beagle dogs. [PDF]
Ge F-f +7 more
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Viral vector- and virus-like particle-based vaccines against infectious diseases: A minireview. [PDF]
Henríquez R, Muñoz-Barroso I.
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Hybrid Ty Virus-Like Particles
International Reviews of Immunology, 1994Vaccines need to activate antigen presenting cells, overcome genetic restriction in T-cell responses and elicit both T and B memory cells. In order to produce recombinant vaccines which can do this, considerable effort has been put into developing particulate antigen presentation systems to generate polyvalent, high molecular weight antigens which ...
S E, Adams +3 more
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Virus-like particles as immunogens
Trends in Microbiology, 2003Subunit vaccines based on recombinant proteins can suffer from poor immunogenicity owing to incorrect folding of the target protein or poor presentation to the immune system. Virus-like particles (VLPs) represent a specific class of subunit vaccine that mimic the structure of authentic virus particles.
Rob, Noad, Polly, Roy
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Virus-like particles in leukaemia
Experimental pathology, 1984Hitherto intracytoplasmic virus-like particles have not been observed simultaneously in nucleus and cytoplasm in human lymphoblasts. We analysed 20 cases of lymphoblastic leukaemia in children and found some virus-like particles in cytoplasm (12 cases) and both in nucleus and cytoplasm (4 cases).
T, Slubowski, M, Kujawa
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Superfluorescent Virus-like Particles
OSA Advanced Photonics Congress 2021, 2021After short pulse excitation, the optical emission from a dense array of fluorophores attached onto the surface of an icosahedral virus is strongly accelerated. Here we review the circumstances in which this intriguing phenomenon can be observed.
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Bioengineering virus‐like particles as vaccines
Biotechnology and Bioengineering, 2013ABSTRACTVirus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory properties of natural viruses while omitting the infectious trait. VLPs that assemble from a single protein have been shown to be safe and highly efficacious in humans, and highly profitable.
Lua, Linda H. L. +5 more
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