Results 201 to 210 of about 274,288 (315)
An enterovirus A71 virus-like particle with replaced loops confers partial cross-protection in mice. [PDF]
Liu X+9 more
europepmc +1 more source
Arf1 defects activate the AKT‐mTORC1‐SREBP1‐FASN pathway to increase lipid synthesis and disrupt ER‐mitochondrial‐lysosomal homeostasis in neurons. Impaired mitochondria secrete damaged mtDNA via mitochondria‐derived extracellular vesicles, which is phagocytosed by the microglia and activated inflammation signaling.
Xu Li+10 more
wiley +1 more source
Targeting of phosphorylated tau at threonine 181 by a Qβ virus-like particle vaccine is safe, highly immunogenic, and reduces disease severity in mice and rhesus macaques. [PDF]
Maphis NM+20 more
europepmc +1 more source
PANEs are specifically designed to enhance the brain delivery efficiency of circDYM compared to commercialized lipid nanoparticles (LNPs). Intranasal administration of PANE‐circDYM effectively alleviated LPS‐induced depressive‐like behaviors by mitigating neuroinflammation and promoting neuroplasticity.
Feng Gao+11 more
wiley +1 more source
Intracellular Virus-like Particles in Lentinus edodes
R. Ushiyama, Y. Nakai
openalex +1 more source
Serological responses to human papillomavirus type 6 and 16 virus-like particles in patients with cervical neoplastic lesions [PDF]
Toshiyuki Sasagawa+7 more
openalex +1 more source
Letter: Hepatitis A virus-like particles. [PDF]
S. G. Lamb+5 more
openaire +3 more sources
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang+8 more
wiley +1 more source