Results 241 to 250 of about 368,709 (305)

STING Agonist-Loaded Physalis Mottle Virus-like Particles as a Potent Prophylactic for Metastatic Melanoma. [PDF]

ACS Appl Mater Interfaces
Simms A, Affonso de Oliveira JF, Steinmetz NF.   +2 more
europepmc   +1 more source

NIR‐II Imaging‐Guided Photothermal Activation of a TRPV4‐Targeted Nanoplatform Delivering Cycloastragenol to Promote Microglia Reprogramming and α‐Synuclein Clearance in Parkinson's Disease

Advanced Science, EarlyView.
ABSTRACT Current therapies for Parkinson's disease (PD) fail to concurrently address α‐synuclein (α‐syn) aggregation and microglia‐mediated neuroinflammation. Herein, we engineer a near‐infrared‐II (NIR‐II) phototheranostic nanoplatform, CAG/FD1080@MM‐aTRPV4, for synergistic regulation of microglial function and real‐time monitoring of PD pathology. We
Hsuan Lo, Linjuan Feng, Shiying Li, Lik Hang Hugo Tse, Xuehan Wang, Xingyang Zhao, Shaoheng Ma, Xin Li, Yanjuan Gu, Wing‐Tak Wong   +9 more
wiley   +1 more source

Improved mRNA-based RSV vaccine with PreF forming enveloped virus-like particles. [PDF]

NPJ Vaccines
Chai P, Shi Y, Li X, Yang M, Liu X, Liu M, Yu J, Yin X, Li D, Li K, Kong X, Zhang Q, Wang H, Sun X, Li J, Li L, Li D, Pang L, Lu X, Duan Z.   +19 more
europepmc   +1 more source

Early Detection and Inhibition of Post‐Surgical Cancer Recurrence by Synthetic Extracellular Vesicles

Advanced Science, EarlyView.
An implantable hydrogel is designed to hold gene transfection agents engineered to turn early recurrent tumor cells into generators of synthetic EVs. These synthetic EVs can express engineered miR‐26a (E‐miR‐26a) for highly sensitive detection and PD‐1 (a PD‐L1‐blocking agent) for therapeutic intervention, thereby enabling early detection and ...
Junli Zhang, Wenjia Chang, Ruolin Hu, Peiyan Su, Qin Zhou, Yanan Li, Zhenzhong Zhang, Kaixiang Zhang   +7 more
wiley   +1 more source

Platform Process for an Autonomous Production of Virus-like Particles. [PDF]

ACS Omega
Baukmann S, Hengelbrock A, Katsoutas K, Stitz J, Schmidt A, Strube J.   +5 more
europepmc   +1 more source

Self-assembly and immunogenicity of virus-like particles from goose astrovirus 1 structural protein following proteolytic maturation in a baculovirus system. [PDF]

Poult Sci
Wang A, Wu Z, Liu L, Zhou Q, Cheng Y, Jia W, Lu H, Xie J, Zhu S.   +8 more
europepmc   +1 more source

Development of Methods to Produce SARS CoV-2 Virus-Like Particles at Scale. [PDF]

Biotechnol Bioeng
Edeling MA, Earnest L, Carrera Montoya J, Yap AHY, Mumford J, Roberts J, Wong CY, Hans D, Grima J, Bisset N, Bodle J, Rockman S, Torresi J.   +12 more
europepmc   +1 more source

Engineering virus-like particles for safe and versatile modeling of SARS-CoV-2 host interaction and immune escape. [PDF]

Commun Biol
Ma L, Lin Y, Ma S, Chen K, Lin Y.
europepmc   +1 more source

mRNA vaccine expressing enterovirus D68 virus-like particles induces potent neutralizing antibodies and protects against infection. [PDF]

Mol Ther Nucleic Acids
Kunishima Y, Senpuku K, Kataoka-Nakamura C, Hirai T, Yoshioka Y.   +4 more
europepmc   +1 more source