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Erratum to "Dual-Stage Cross-Flow Filtration: Integrated Capture and Purification of Virus-Like Particles". [PDF]
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Hybrid Ty Virus-Like Particles
International Reviews of Immunology, 1994Vaccines need to activate antigen presenting cells, overcome genetic restriction in T-cell responses and elicit both T and B memory cells. In order to produce recombinant vaccines which can do this, considerable effort has been put into developing particulate antigen presentation systems to generate polyvalent, high molecular weight antigens which ...
S E, Adams +3 more
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Virus-like particles as immunogens
Trends in Microbiology, 2003Subunit vaccines based on recombinant proteins can suffer from poor immunogenicity owing to incorrect folding of the target protein or poor presentation to the immune system. Virus-like particles (VLPs) represent a specific class of subunit vaccine that mimic the structure of authentic virus particles.
Rob, Noad, Polly, Roy
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Virus-like particles in leukaemia
Experimental pathology, 1984Hitherto intracytoplasmic virus-like particles have not been observed simultaneously in nucleus and cytoplasm in human lymphoblasts. We analysed 20 cases of lymphoblastic leukaemia in children and found some virus-like particles in cytoplasm (12 cases) and both in nucleus and cytoplasm (4 cases).
T, Slubowski, M, Kujawa
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Superfluorescent Virus-like Particles
OSA Advanced Photonics Congress 2021, 2021After short pulse excitation, the optical emission from a dense array of fluorophores attached onto the surface of an icosahedral virus is strongly accelerated. Here we review the circumstances in which this intriguing phenomenon can be observed.
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Bioengineering virus‐like particles as vaccines
Biotechnology and Bioengineering, 2013ABSTRACTVirus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory properties of natural viruses while omitting the infectious trait. VLPs that assemble from a single protein have been shown to be safe and highly efficacious in humans, and highly profitable.
Lua, Linda H. L. +5 more
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Annual Review of Microbiology, 1980
INTRODUCTION ......... .. ..... ..... ..... .. ... ....... 49 The Killer Character 50 The killing reaction ....... ..... 51 Other killer systems .. ......... ......... ..... ...... ...... 51 ScVas a model system 52 PHYSICAL PROPERTIES OF ScV PARTICLES 52 CAPSID POLYPEPTIDES ........ 55 ScV RNAs 56 Structure .. .
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INTRODUCTION ......... .. ..... ..... ..... .. ... ....... 49 The Killer Character 50 The killing reaction ....... ..... 51 Other killer systems .. ......... ......... ..... ...... ...... 51 ScVas a model system 52 PHYSICAL PROPERTIES OF ScV PARTICLES 52 CAPSID POLYPEPTIDES ........ 55 ScV RNAs 56 Structure .. .
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Enzyme Stabilization by Virus-Like Particles
Biochemistry, 2020The properties of enzymes packaged within the coat protein shell of virus-like particles (VLPs) were studied to provide a comprehensive assessment of such factors. Such entrainment did not seem to perturb enzyme function, but it did significantly enhance enzyme stability against several denaturing stimuli such as heat, organic solvents, and chaotropic ...
Soumen Das +3 more
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Transcutaneous vaccination with virus-like particles
Vaccine, 2006Virus-like particles (VLP) are inert, empty capsids of viruses, which contain no DNA/RNA from the virus itself. However they retain the structure of a virus and they can be engineered to have antigens attached. We have constructed VLP, derived from Rabbit hemorrhagic disease virus, and shown they are highly immunogenic.
Young, Sarah +5 more
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Meningoencephalitis with toroidal virus-like particles
Acta Neuropathologica, 1975A previously healthy middle aged man died following a 6 month illness which presented with middle ear symptoms, apparently resolved, and then 2 months later manifested as encephalitis. The illness was characterized initially by depression and intellectual deterioration. No family member or working associate was affected. The clinical diagnosis of viral
H C, Powell, A I, Braude, P W, Lampert
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