Results 171 to 180 of about 5,701,493 (405)
Evaluation of Artificial Intelligence-generated Responses to Common Plastic Surgery Questions
Plastic and Reconstructive Surgery, Global Open, 2023 Hinpetch Daungsupawong, PhD +1 more
doaj +1 more source
Roles of the membrane-reentrant β-hairpin-like loop of RseP protease in selective substrate cleavage
eLife, 2015 Molecular mechanisms underlying substrate recognition and cleavage by Escherichia coli RseP, which belongs to S2P family of intramembrane-cleaving proteases, remain unclear.
Koichiro Akiyama +5 more
doaj +1 more source
How many infections of COVID-19 there will be in the "Diamond Princess"-Predicted by a virus transmission model based on the simulation of crowd flow [PDF]
arXiv, 2020 Objectives: Simulate the transmission process of COVID-19 in a cruise ship, and then to judge how many infections there will be in the 3711 people in the "Diamond Princess" and analyze measures that could have prevented mass transmission. Methods: Based on the crowd flow model, the virus transmission rule between pedestrians is established, to ...
arxiv
Trends in Microbiology, 2018 This infographic briefly summarises the natural history, replication cycle, and pathogenesis of influenza viruses, the cause of seasonal influenza and of influenza pandemics. Influenza viruses infect many vertebrates, with Influenza A, B and C viruses (IAV, IBV, and ICV) infecting humans. High mutation rates allow the evasion of immunity.
openaire +3 more sources
Molecular Oncology, EarlyView.Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu +11 more
wiley +1 more source
Implications of the virus-encoded miRNA and host miRNA in the pathogenicity of SARS-CoV-2 [PDF]
arXiv, 2020 The outbreak of COVID-19 caused by SARS-CoV-2 has rapidly spread worldwide and has caused over 1,400,000 infections and 80,000 deaths. There are currently no drugs or vaccines with proven efficacy for its prevention and little knowledge was known about the pathogenicity mechanism of SARS-CoV-2 infection.
arxiv
Molecular Oncology, EarlyView.Microglia act as tumor suppressors during brain metastasis colonization but shift to a tumor‐promoting role after melanoma brain metastases form. NF‐κB/RelA signaling emerges as a key driver of this phenotypic shift. Targeting this pathway reprograms microglia into a pro‐inflammatory state, enhancing antitumor immunity and immune checkpoint inhibitor ...
Noam Savion‐Gaiger +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu +11 more
wiley +1 more source
EPIDEMIOLOGIC AND IMMUNOLOGIC SIGNIFICANCE OF AGE DISTRIBUTION OF ANTIBODY TO ANTIGENIC VARIANTS OF INFLUENZA VIRUS [PDF]
, 1953 Fred M. Davenport +2 more
openalex +1 more source