Results 41 to 50 of about 4,195,312 (308)
Mutagenesis of the conserved 51-nucleotide region of Sindbis virus [PDF]
We have constructed 25 site-specific mutations in a domain of 51 nucleotides in Sindbis virus that is highly conserved among all alphaviruses sequenced to date.
Niesters, Hubert G. M. +1 more
core
We examine virus maturation of selected nonenveloped and enveloped single-stranded RNA viruses, retroviruses, bacteriophages, and herpesviruses. Processes associated with maturation in the RNA viruses range from subtle (nodaviruses and picornaviruses) to dramatic (tetraviruses and togaviruses).
David, Veesler, John E, Johnson
openaire +2 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Paralytic cases associated with the administration of oral live poliomyelitis vaccine
During mass immunization of oral poliomyelitis vaccine in Bangkok from January to May 1969, 13 paralytic cases associated with poliomyelitis vaccine were reported.
Nadhirat Sangkawibha +2 more
doaj
In recent years, different computing models have emerged within the area of Unconven-tional Computation, and more specifically within Natural Computing, getting inspiration from mechanisms present in Nature.
Chen, Xu +4 more
core +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Arthropod-borne disease challenges from planetary warming, urbanization, and migration
As the world confronts simultaneous climate and health emergencies, the spread of emerging infectious diseases, particularly arboviruses, underscores the intersection of planetary health, global mobility, and disease risk. Viral pathogens like Oropouche,
Maggie L. Bartlett +3 more
doaj +1 more source
Vpu and BST2: still not there yet?
Extensive investigations have identified two cellular proteins in humans that potently inhibit HIV-1 replication and are widely accepted as ‘restriction factors’.
Kei eSato +3 more
doaj +1 more source
Adsorption of MS2 bacteriophage on ultrafiltration membrane laboratory equipments [PDF]
Virus adsorption has been quantified (i) on different materials including various containers made of glass, plastic or stainless steel and hollow fiber membranes made of polyethersulfone, polysulfone, PVDF or cellulose acetate (with two configurations ...
Aimar, Pierre +3 more
core +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

