Results 71 to 80 of about 2,627,962 (316)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Canadian Public Health Laboratory Network Statement on Point-of-Care Serology Testing in COVID-19

Canada Communicable Disease Report, 2022
Respiratory Virus Infections Working Group
doaj   +1 more source

The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution

Nature Communications
Avian influenza H5N1 clade 2.3.4.4b viruses caused a global panzootic and, unexpectedly, widespread outbreaks in dairy cattle, therefore representing a pandemic threat.
Matthew L. Turnbull, Mohammad Khalid Zakaria, Nicole S. Upfold, Siddharth Bakshi, Callum Magill, Udeet Ranjan Das, Andrew T. Clarke, Laura Mojsiejczuk, Vanessa Herder, Kieran Dee, Nancy Liu, Monika Folwarczna, Georgios Ilia, Wilhelm Furnon, Verena Schultz, Hanting Chen, Ryan Devlin, Jack McCowan, Alex L. Young, Wai-Wai Po, Katherine Smollett, Muhammad Ahsan Yaseen, Rebecca Ross, Avanti Bhide, Bianca van Kekem, Ron A. M. Fouchier, Ana da Silva Filipe, Munir Iqbal, Ed Roberts, Joseph Hughes, Dirk Werling, Pablo R. Murcia, Massimo Palmarini   +32 more
doaj   +1 more source

Respiratory syncytial virus infection in infants and correlation with meteorological factors and air pollutants [PDF]

, 2013
Silvia Vandini, Luigi Corvaglia, Rosina Alessandroni, Giulia Aquilano, Concetta Marsico, M. Spinelli, Marcello Lanari, Giacomo Faldella   +7 more
openalex   +1 more source

Virus nuevos, viejos virus

Enfermedades Infecciosas y Microbiología Clínica, 2007
Probablemente esta misma estrategia fue la que ayudo a controlar con eficacia el brote del sindrome respiratorio grave y agudo (SARS) que tanto alarmo a la comunidad internacional durante la primavera del 20033. Este brote sin precedentes demostro la eficacia con la que la comunidad cientifica pudo identificar un nuevo patogeno, proponer metodos de ...
openaire   +1 more source

Chikungunya Virus

Clinics in Laboratory Medicine, 2017
For chikungunya virus (CHIKV), the long-term sequelae from infection are yet ill-defined. The prolonged debilitating arthralgia associated with CHIKV infection has tremendous potential for impacting the global economy and should be considered when evaluating the human burden of disease and the allocation of resources.
Vu, David M., Jungkind, Donald, Angelle Desiree LaBeaud   +2 more
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Epstein-Barr Virus Oncoprotein Super-enhancers Control B Cell Growth [PDF]

, 2015
Hufeng Zhou, Stefanie C.S. Schmidt, Sizun Jiang, Bradford Willox, Katharina Bernhardt, Jun Liang, Eric Johannsen, Peter V. Kharchenko, Benjamin E. Gewurz, Elliott Kieff, Bo Zhao   +10 more
openalex   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source