Results 91 to 100 of about 28,539 (272)

Mortalidad asociada con las temporadas de mayor circulación de los virus de la influenza en Bogotá, Colombia, 1997-2005 [PDF]

, 2009
Alexandra Porras, Alejandro Mendoza, José Moreno‐Montoya, Karol Cótes, Juan Diego López, Diana Herrera, Gloria Rey-Benito, Fernando de la Hoz   +7 more
openalex   +1 more source

USP10 Inhibits Ferroptosis via Deubiquinating POLR2A in Head and Neck Squamous Cell Carcinoma

Advanced Science, EarlyView.
This study identifies USP10 as a novel deubiquitinase that antagonizes ferroptosis in head and neck squamous cell carcinoma (HNSCC). Mechanistically, USP10 directly stabilizes POLR2A protein through post‐translational deubiquitination, enabling POLR2A‐mediated transcriptional activation of SLC7A11, a key ferroptosis inhibitor.
Diekuo Zhang, Xueying Wang, Shanhong Lu, Yan Gao, Gangcai Zhu, Guo Li, Zongnan Yu, Junwei Hou, Helei Yan, Wenhui Yuan, Xin Zhang, Mien‐Chie Hung, Zhifeng Liu, Yong Liu   +13 more
wiley   +1 more source

Tumor‐Associated Sympathetic Nerves Promote the Progression of Epstein‐Barr Virus‐Positive Diffuse Large B‐Cell Lymphoma

Advanced Science, EarlyView.
Sympathetic nerve innervation promotes the progression of Epstein‐Barr virus‐positive diffuse large B‐cell lymphoma (EBV+ DLBCL) via β2‐adrenergic receptors. The discovery of enhanced nerve infiltration and β2AR expression reveals a novel mechanism and highlights the sympathetic–β2AR axis as a promising target for therapeutic intervention in EBV+ DLBCL.
Silan Huang, Dexin Lei, Linbin Yang, Aiwei Bi, Yanlou Wang, Peng Zhang, Dongyu Zhuang, Honglian Liu, Qingqing Cai, Man Nie, Yi Xia   +10 more
wiley   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Enfermedad tipo influenza en el Hospital Pediátrico de Moa. Enero-agosto 2010

Medisur, 2013
Fundamento: La enfermedad respiratoria producida por el virus de influenza A H1N1, constituyó la primera pandemia de influenza del siglo XXI, provocando gran morbilidad y miles de fallecidos, los daños no fueron mayores gracias a que el virus no mutó a ...
Luis Angel Osorio Góngora, Noralis Concepción RodrÍguez, Edelmis Pérez Salomón, Dianeyis Silot Oliveros, Ailen Rodríguez Díaz   +4 more
doaj   +2 more sources

Influenza virus A H5N1 and H1N1: features and zoonotic potential Virus de Influenza A H5N1 y H1N1: características y potencial zoonótico Os virus da Influenza A H5N1 e H1N1: características e potencial zoonótico

Revista Colombiana de Ciencias Pecuarias, 2011
Influenza A viruses which belong to the Orthomyxoviridae family, are enveloped, pleomorphic, and contain genomes of 8 single-stranded negative-sense segments of RNA. Influenza viruses have three key structural proteins: hemagglutinin (HA), neuraminidase (
Diana M Echeverry, Juan D Rodas
doaj  

Asociación entre la seropositividad al virus de influenza porcina (VIP) y las características de las granjas tecnificadas porcícolas en Colombia [PDF]

, 2016
Johanna Paola Corrales, Pilar Pineda, Luis Felipe Ortiz Castro, Diana Corina Zambrano Moreno   +3 more
openalex   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Crisis miasténica asociada a influenza A H1N1. Presentación de un caso Myasthenic crisis associated with `Influenza' A (H1N1) virus. A case report

Revista de Ciencias Médicas de Pinar del Río, 2012
La infección con influenza estacional es extremadamente común y aunque causa predominantemente enfermedad respiratoria, se ha asociado con una amplia variedad de complicaciones neurológicas.
Heydi Flores Podadera, Osbert Rodríguez Miranda, Yanet Flores Podadera, José Nelet Rodríguez García   +3 more
doaj  

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

Advanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao, Lingxue Niu, Zhihao Wang, Di Dai, Shasha Tang, Xiaoding Ma, Zhenqiang Deng, Guiling Yu, Yang Zhou, Tao Yan, Xingwan Liu, Deqiang Kong, Linfeng Hu, Xiang Li, Junwei Zhao, Fengfeng Cai, Meiyan Wang, Haifeng Ye   +17 more
wiley   +1 more source