Results 221 to 230 of about 43,232 (314)

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Asociación entre la seropositividad al virus de influenza porcina (VIP) y las características de las granjas tecnificadas porcícolas en Colombia

, 2016
Johanna Paola Corrales, Pilar Pineda, Luis Felipe Ortiz Castro, Diana Corina Zambrano Moreno, Diana Corina Zambrano Moreno   +4 more
openalex   +1 more source

Monitoring effectiveness of nirsevimab immunization against RSV hospitalization using surveillance data: a test-negative case-control study, Spain, October 2024-March 2025. [PDF]

Epidemiol Infect
Campos Mena S, Pérez-Gimeno G, Lorusso N, Álvarez Río V, Basile L, Batalla Rebollo N, García-Comas L, Andreu Ivorra B, Pérez-Panadés J, Ramos Marín V, Castrillejo D, Fernández Ibáñez A, Rafael de la Cruz López MÁ, Núñez O, Monge S, SiVIRA group.   +15 more
europepmc   +1 more source

Non‐Targeting shRNA‐Encoded Plasmid DNA Enhances Protective Immunity Through RIDD‐RIG‐I Signaling Pathway in the Zika Virus Animal Model

Advanced Science, EarlyView.
We present a novel DNA vaccine platform featuring intrinsic, non‐targeting dsRNA that significantly enhances immune responses by activating the regulated IRE1‐dependent decay‐RIG‐I signaling pathway. This research elucidates a previously uncharacterized mechanism for dsRNA‐mediated innate immune activation.
Min‐Syuan Huang, Hung‐Chun Liao, Po Peng, Wan‐Ling Wu, Kit Man Chai, Mei‐Yu Chen, Guann‐Yi Yu, Tsung‐Hsien Chuang, Hsin‐Wei Chen, Chuang‐Rung Chang, Shih‐Jen Liu   +10 more
wiley   +1 more source

La pandemia del virus de la influenza a h1n1 en el 2009 [PDF]

, 2009
Javier Ramos Jiménez
openalex  

Circumpolar spread of avian influenza H5N1 to southern Indian Ocean islands. [PDF]

Nat Commun
Clessin A, Briand FX, Tornos J, Lejeune M, De Pasquale C, Fischer R, Souchaud F, Hirchaud E, Hong SL, Bralet T, Guinet C, McMahon CR, Grasland B, Baele G, Boulinier T.   +14 more
europepmc   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, EarlyView.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Desarrollo de un nuevo antígeno contra el virus de la influenza aviar basado en la fusión de dominios expuestos de la hemaglutinina viral del subtipo H5 y la proteína CD154 de Gallus gallus [PDF]

, 2012
A. González, Julia Noda, Armando Vega, Alina Venereo, Elsa Rodríguez, Maria Pilar Rodríguez, Ernesto M González, Damarys Concepción Díaz, Raquel Montesino, Elaine Santana, Carlos Montero, Alina Rodrı́guez, Mario Pablo Estrada, C.G Borroto   +13 more
openalex  

Influenza virus and Staphylococcus aureus super-infection disrupts spatially coordinated cellular immunity in the mouse lung. [PDF]

Commun Biol
Liu T, Miller LM, Dresden BP, Zhao C, Pillai Y, Rangel-Garcia A, Garcia-Hernandez ML, Rangel-Moreno J, Chen W, Alcorn JF.   +9 more
europepmc   +1 more source

MARPLE: A Proximity‐Triggered CRISPR‐Cas13 Platform for Ultrasensitive Antibody Detection

Advanced Science, EarlyView.
MARPLE is a modular CRISPR‐Cas13 immunoassay that uses antibody‐induced proximity to trigger a toehold‐exchange reaction, releasing an RNA activator for Cas13. This one‐pot, isothermal architecture enables ultrasensitive (femtomolar) and highly specific detection of diverse antibodies, including therapeutic, pathogen‐specific, and cancer‐associated ...
Elena Spezzani, Luca Capelli, Denise Di Lena, Alejandro Chamorro‐Garcia, Rudy Ippodrino, Alessandro Porchetta, Alessandro Bertucci   +6 more
wiley   +1 more source