Results 51 to 60 of about 28,539 (272)

On the Spread of the Novel Influenza A (H1N1) Virus in Mexico

The Journal of Infection in Developing Countries, 2009
فيروس الأنفلونزا A H1N1 الجديد من أصل خنازير هو المسؤول عن وباء الأنفلونزا الذي يؤثر على المكسيك والولايات المتحدة الأمريكية و 39 دولة أخرى. في حين أن أصل هذا العامل الممرض الناشئ لا يزال غير مؤكد، فقد لوحظت زيادة في حالات الإصابة بأمراض الجهاز التنفسي المبلغ عنها خلال مارس 2009 في مدينة لا غلوريا، في ولاية فيراكروز جنوب شرق المكسيك.
Malaquías López‐Cervantes, Aida Venado, Andrés Moreno, Reyna Lizette Pacheco-Domínguez, Guadalupe Ortega‐Pierres   +4 more
openaire   +5 more sources

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

Advanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput, Yen‐Ting Tung, Yu‐Chi Chen, Min Jae Song, Marc Ferrer, Emily M. Lee   +5 more
wiley   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

Influenzas humana y aviar: amenaza de una pandemia humana

Acta Médica Peruana, 2006
La influenza es una enfermedad respiratoria aguda causada por la infección de un grupo de agentes virales conocidos como virus de la influenza A, B y C (VI-A, VI-B y VI-C), los cuales pueden afectar tanto al hombre como a diversas especies animales ...
Fernando Osores Plenge, César Cabezas Sánchez, Jorge Gómez Benavides, Ciro Maguiña Vargas   +3 more
doaj   +1 more source

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Influenza-related mortality in Spain, 1999-2005 Mortalidad relacionada con la gripe. España, 1999-2005

Gaceta Sanitaria, 2012
Objective: To estimate the excess deaths attributed to influenza in Spain, using age-specific generalized linear models (GLM) and the Serfling model for the period 1999-2005. Method: We reviewed mortality from influenza and pneumonia and all-cause deaths.
Teresa López-Cuadrado, Salvador de Mateo, Silvia Jiménez-Jorge, Camelia Savulescu, Amparo Larrauri   +4 more
doaj   +1 more source

Magnetic‐Driven Torque‐Induced Electrical Stimulation for Millisecond‐Scale Wireless Neuromodulation

Advanced Healthcare Materials, EarlyView.
MagTIES is a wireless neuromodulation technique with millisecond precision. It employs magnetic‐driven torque from magnetite nanodiscs to activate piezoelectric nanoparticles, enabling precise temporal control of neuronal activity and brain oscillations using weak, low‐frequency magnetic fields.
Chao‐Chun Cheng, Li‐Ling Chen, Guan‐Jhong Tseng, Jun‐Xuan Huang, Yen‐Jing Ting, Po‐Han Chiang   +5 more
wiley   +1 more source

Factores de riesgo asociados a mortalidad por nueva influenza A (H1N1) en la región Cusco-Perú

Acta Médica Peruana, 2013
Introducción: En la Región Cusco durante el 2009, se reportaron 395 casos confirmados de nueva influenza A(H1N1) y 15 defunciones. La tasa de letalidad del 3.8%, estuvo muy por encima de reportes nacionales e internacionales, constituyéndose en serio ...
Pablo F. Grajeda Annca, Oscar Filipo Niño de Guzmán, Manuel Montoya Lizarraga, Yuri Guevara Fernández   +3 more
doaj  

Design and Validation of Hybrid Polymer‐Lipid Nanoparticles as Novel Transfection Vectors for MicroRNA Delivery to Human Cardiac Fibroblasts

Advanced Healthcare Materials, EarlyView.
Hybrid NPs are developed as efficient, scalable nanocarriers for in vitro microRNA delivery, ensuring high loading efficiency, controlled release, physiological and long‐term storage stability. They outperform commercial lipid‐based reagents in terms of transfection efficiency and biocompatibility.
Letizia Nicoletti, Camilla Paoletti, Martina Coletto, Elena Marcello, Giovanni Paolo Stola, Francesca Cossetta, Francesco Schiavone, Ilaria Andreana, Barbara Stella, Silvia Arpicco, Clara Mattu, Valeria Chiono   +11 more
wiley   +1 more source