Results 91 to 100 of about 4,863,377 (394)

Genetic variation and evolutionary characteristics of Echovirus 11: new variant within genotype D5 associated with neonatal death found in China

Emerging Microbes and Infections
Echovirus 11 (E11) has gained attention owing to its association with severe neonatal infections. From 2018 to 2023, a surge in severe neonatal cases and fatalities linked to a novel variant of genotype D5 was documented in China, France, and Italy ...
Liu Ying, Sun Qiang, Xiao Jinbo, Ren Binzhi, Zhao Hua, Shi Yong, Zhou Shuaifeng, Hong Mei, Zhou Kangping, Cun Jianping, Zeng Yunting, Chen Jianhua, Ge Qiong, Ju Yu, Lu Huanhuan, Li Jichen, Cong Ruyi, Yang Tingting, Wang Rui, Zong Yanjun, Sun Tiantian, Yu Liheng, Wang Xiaoyi, Zhu Shuangli, Yan Dongmei, Ji Tianjiao, Yang Qian, Zhu Zhen, Zhang Yong   +28 more
doaj   +1 more source

Phylogeographic Dynamics of Influenza A(H9N2) Virus Crossing Egypt

Frontiers in Microbiology, 2020
Low pathogenic avian influenza (LPAI) virus of subtype H9N2 is the most frequently detected subtype among domestic poultry and is a public health concern because of its zoonotic potential.
Ruiyun Li, Amany Adel, Jon Bohlin, Åke Lundkvist, Björn Olsen, John H.-O. Pettersson, John H.-O. Pettersson, Mahmoud M. Naguib, Mahmoud M. Naguib   +8 more
doaj   +1 more source

Outbreak of West Nile virus causing severe neurological involvement in children, Nuba Mountains, Sudan, 2002. [PDF]

, 2004
An atypical outbreak of West Nile virus (WNV) occurred in Ngorban County, South Kordophan, Sudan, from May to August 2002. We investigated the epidemic and conducted a case-control study in the village of Limon.
Anonymous (MMWR), Berthet FX, Chowers MY, George S, Hayes CG, Huang C, Hubalek Z, Kohler KA, Le Guenno B, Marberg K, McGuigan CC, McLean RG, Murgue B, Murgue B, Petersen LR, Petersen LR, Platonov AE, Solomon T, Taylor RM, Watts DM, Weinberger M   +20 more
core   +2 more sources

Harnessing host–virus evolution in antiviral therapy and immunotherapy

Clinical & Translational Immunology, 2019
Pathogen resistance and development costs are major challenges in current approaches to antiviral therapy. The high error rate of RNA synthesis and reverse‐transcription confers genome plasticity, enabling the remarkable adaptability of RNA viruses to ...
Steven M Heaton
semanticscholar   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Polyomavirus T Antigen Induces APOBEC3B Expression Using an LXCXE-Dependent and TP53-Independent Mechanism

mBio, 2019
APOBEC3B is a single-stranded DNA cytosine deaminase with beneficial innate antiviral functions. However, misregulated APOBEC3B can also be detrimental by inflicting APOBEC signature C-to-T and C-to-G mutations in genomic DNA of multiple cancer types ...
Gabriel J. Starrett, Artur A. Serebrenik, Pieter A. Roelofs, Jennifer L. McCann, Brandy Verhalen, Matthew C. Jarvis, Teneale A. Stewart, Emily K. Law, Annabel Krupp, Mengxi Jiang, John W. M. Martens, Ellen Cahir-McFarland, Paul N. Span, Reuben S. Harris   +13 more
doaj   +1 more source

Evidence for RNA recombination between distinct isolates of Pepino mosaic virus. [PDF]

, 2010
Genetic recombination plays an important role in the evolution of virus genomes. In this study we analyzed publicly available genomic sequences of Pepino mosaic virus (PepMV) for recombination events using several bioinformatics tools.
Hasiów-Jaroszewska, B., Kuzniar, A., Leunissen, J.A.M., Peters, S.A., Pospieszny, H.   +4 more
core   +1 more source

Virus evolution in Wolbachia-infected Drosophila

Proceedings of the Royal Society B, 2019
Wolbachia, a common vertically transmitted symbiont, can protect insects against viral infection and prevent mosquitoes from transmitting viral pathogens.
Julien Martinez, Gaspar Bruner-Montero, Ramesh Arunkumar, Sophia C. L. Smith, Jonathan P Day, B. Longdon, F. Jiggins   +6 more
semanticscholar   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Subterranean Clover Stunt Virus Revisited: Detection of Two Missing Genome Components

Viruses, 2019
Subterranean clover stunt virus (SCSV) is a type species of the genus Nanovirus in the family Nanoviridae. It was the first single-stranded DNA plant virus with a multipartite genome, of which genomic DNA sequences had been determined.
Dennis Knierim, Quentin Barrière, Ioana Grigoras, Stephan Winter, Heinrich-Josef Vetten, Mark Schwinghamer, John Thomas, Paul Chu, Bruno Gronenborn, Tatiana Timchenko   +9 more
doaj   +1 more source