Multiple reassortment events in the evolutionary history of H1N1 influenza A virus since 1918 [PDF]
, 2008 The H1N1 subtype of influenza A virus has caused substantial morbidity and mortality in humans, first documented in the global pandemic of 1918 and continuing to the present day.
A Isaacs +48 more
core +8 more sources
Neolithic and medieval virus genomes reveal complex evolution of hepatitis B
eLife, 2018 The hepatitis B virus (HBV) is one of the most widespread human pathogens known today, yet its origin and evolutionary history are still unclear and controversial.
Ben Krause-Kyora +21 more
doaj +1 more source
Evolution of foot-and-mouth disease virus intra-sample sequence diversity during serial transmission in bovine hosts [PDF]
, 2013 RNA virus populations within samples are highly heterogeneous, containing a large number of minority sequence variants which can potentially be transmitted to other susceptible hosts. Consequently, consensus genome sequences provide an incomplete picture
Haydon, D.T. +6 more
core +2 more sources
eLife, 2017 This study defined the genetic epidemiology of dengue viruses (DENV) in two pivotal phase III trials of the tetravalent dengue vaccine, CYD-TDV, and thereby enabled virus genotype-specific estimates of vaccine efficacy (VE).
Maia A Rabaa +13 more
doaj +1 more source
Longitudinal sequencing of HIV-1 infected patients with low-level viremia for years while on ART shows no indications for genetic evolution of the virus [PDF]
, 2017 HIV-infected patients on antiretroviral therapy (ART) may present low-level viremia (LLV) above the detection level of current viral load assays.
Dauwe, Kenny +7 more
core +1 more source
Virus Evolution: Fitting Lifestyles to a T [PDF]
Current Biology, 2005 The structure of a double-stranded RNA virus outer shell has revealed unexpected similarities with virions of positive-strand RNA viruses. These similarities intersect with emerging parallels in RNA replication to create intriguing evolutionary possibilities.
openaire +3 more sources
Exceptional Convergent Evolution in a Virus [PDF]
Genetics, 1997 Abstract Replicate lineages of the bacteriophage ϕX 174 adapted to growth at high temperature on either of two hosts exhibited high rates of identical, independent substitutions. Typically, a dozen or more substitutions accumulated in the 5.4-kilobase genome during propagation. Across the entire data set of nine lineages, 119 independent
Ian J. Molineux +7 more
openaire +3 more sources
Viruses, 2022 The highly pathogenic avian influenza (HPAI) H5N8 virus was first detected in Egypt in late 2016. Since then, the virus has spread rapidly among different poultry sectors, becoming the dominant HPAI H5 subtype reported in Egypt.
Naglaa M. Hagag +13 more
doaj +1 more source
Inferring stabilizing mutations from protein phylogenies : application to influenza hemagglutinin [PDF]
, 2009 One selection pressure shaping sequence evolution is the requirement that a protein fold with sufficient stability to perform its biological functions.
A Akasako +125 more
core +3 more sources
A multi-group SEIRA model for the spread of COVID-19 among heterogeneous populations [PDF]
, 2020 The outbreak and propagation of COVID-19 have posed a considerable challenge to modern society. In particular, the different restrictive actions taken by governments to prevent the spread of the virus have changed the way humans interact and conceive ...
Biron-Lattes, Juan Pablo +4 more
core +2 more sources