Results 41 to 50 of about 235,095 (169)

What Does Virus Evolution Tell Us About Virus Origins? [PDF]

Journal of Virology, 2011
ABSTRACTDespite recent advances in our understanding of diverse aspects of virus evolution, particularly on the epidemiological scale, revealing the ultimate origins of viruses has proven to be a more intractable problem. Herein, I review some current ideas on the evolutionary origins of viruses and assess how well these theories accord with what we ...
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Genetic Diversity of Infectious Bronchitis Virus Genotype II in Poland

Pathogens
The epidemiological situation in Poland for IBV GII (formerly known as D1466) has seemed stable over the years, but an increase in such infections has been recently reported. In this study, genetic characterization of the representatives of this genotype
Anna Pikuła, Anna Lisowska, Justyna Opolska, Katarzyna Domańska-Blicharz   +3 more
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Evolutionary Insight into the Association between New Jersey Polyomavirus and Humans

Viruses, 2023
Advances in viral discovery techniques have led to the identification of numerous novel viruses in human samples. However, the low prevalence of certain viruses in humans raises doubts about their association with our species.
Aref-Abdolllah Aghebatrafat, Chris Lauber, Kevin Merkel, Barbara Fruth, Kevin Langergraber, Martha M. Robbins, Roman M. Wittig, Fabian H. Leendertz, Sébastien Calvignac-Spencer   +8 more
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Predicting Virus Evolution [PDF]

, 2011
Viruses are an important cause of human disease, often because they are highly transmittable from human to human. A key tool from population genetics that can be applied to the study of viruses is coalescent theory. Coalescent theory predicts genealogical tree shapes as a function of how the studied organisms are evolving.
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Expanding networks of RNA virus evolution [PDF]

BMC Biology, 2012
In a recent BMC Evolutionary Biology article, Huiquan Liu and colleagues report two new genomes of double-stranded RNA (dsRNA) viruses from fungi and use these as a springboard to perform an extensive phylogenomic analysis of dsRNA viruses. The results support the old scenario of polyphyletic origin of dsRNA viruses from different groups of positive ...
Koonin Eugene V, Dolja Valerian V
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Roles of APOBEC3A and APOBEC3B in Human Papillomavirus Infection and Disease Progression

Viruses, 2017
The apolipoprotein B messenger RNA-editing, enzyme-catalytic, polypeptide-like 3 (APOBEC3) family of cytidine deaminases plays an important role in the innate immune response to viral infections by editing viral genomes.
Cody J. Warren, Joseph A. Westrich, Koenraad Van Doorslaer, Dohun Pyeon   +3 more
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Establishing an In Vitro System to Assess How Specific Antibodies Drive the Evolution of Foot-and-Mouth Disease Virus

Viruses, 2022
Viruses can evolve to respond to immune pressures conferred by specific antibodies generated after vaccination and/or infection. In this study, an in vitro system was developed to investigate the impact of serum-neutralising antibodies upon the evolution
David J. King, Graham Freimanis, Chris Neil, Andrew Shaw, Tobias J. Tuthill, Emma Laing, Donald P. King, Lidia Lasecka-Dykes   +7 more
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Evolution of Bovine Respiratory Syncytial Virus [PDF]

Journal of Virology, 2000
ABSTRACTUntil now, the analysis of the genetic diversity of bovine respiratory syncytial virus (BRSV) has been based on small numbers of field isolates. In this report, we determined the nucleotide and deduced amino acid sequences of regions of the nucleoprotein (N protein), fusion protein (F protein), and glycoprotein (G protein) of 54 European and ...
J F, Valarcher, F, Schelcher, H, Bourhy
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Exceptional Convergent Evolution in a Virus [PDF]

Genetics, 1997
Abstract Replicate lineages of the bacteriophage ϕX 174 adapted to growth at high temperature on either of two hosts exhibited high rates of identical, independent substitutions. Typically, a dozen or more substitutions accumulated in the 5.4-kilobase genome during propagation. Across the entire data set of nine lineages, 119 independent
J J, Bull, M R, Badgett, H A, Wichman, J P, Huelsenbeck, D M, Hillis, A, Gulati, C, Ho, I J, Molineux   +7 more
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Virus Evolution and Genetics

, 2017
Viruses are very diverse and they infect organisms from all domains of life and across all ecosystems, but related viruses often infect very different types of organisms, pointing to their very ancient origins. Three commonly proposed mechanisms for the origins of viruses are: Viruses descended from primitive precellular life forms; viruses are escaped
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