Results 41 to 50 of about 143,789 (304)

Molecular mechanism underlying B19 virus inactivation and comparison to other parvoviruses [PDF]

, 2007
BACKGROUND: B19 virus (B19V) is a human patho-gen frequently present in blood specimens. Transmis-sion of the virus occurs mainly via the respiratory route,but it has also been shown to occur through the admin-istration of contaminated plasma-derived ...
Gerber, Marco, Ros, Carlos, Mani, Bernhard, Boschetti, Nicola, Kempf, Christoph, Lieby, Patricia   +5 more
core   +1 more source

Detection of suid herpesvirus 1 infectivity in pigs by propidium monoazide-qPCR

Frontiers in Veterinary Science, 2022
At present, there is no effective experimental method for detecting whether the suid herpesvirus 1 (SHV-1) detected in pigs is infectious. Although the technique of quantitative polymerase chain reaction (qPCR) has significantly improved the detection ...
Liu Yang, Yunzhi Long, Qianqian Li, Wenbo Song, Ying Huang, Gong Liang, Daobing Yu, Mingguang Zhou, Gaoyuan Xu, Yao Chen, Chao Huang, Xibiao Tang   +11 more
doaj   +1 more source

The Heat Inactivation of Vaccinia Virus [PDF]

Journal of General Microbiology, 1958
SUMMARY: Heat inactivation curves of vaccinia virus between 50° and 60° indicate that the virus is heterogeneous in its heat sensitivity. The proportion of heat-resistant particles varies inversely with the temperature of exposure. The inactivation of heat-sensitive virus is temperature dependent and seems to be a first-order reaction, while the heat ...
openaire   +2 more sources

Evaluation of the effectiveness of chemical inactivation and immunogenicity of the Omicron variant of the SARS-CoV-2 virus

Вопросы вирусологии
Introduction. The rapid spread of coronavirus infection COVID-19 among the population of many countries around the world has contributed to the emergence of many genetic variants of SARS-CoV-2.
Gulzhan A. Zhapparova, Balzhan S. Myrzakhmetova, Talshyngul M. Tlenchiyeva, Aiganym A. Tussipova, Karina B. Bissenbayeva, Aizhan S. Toytanova, Lespek B. Kutumbetov   +6 more
doaj   +1 more source

Harnessing Hazara Virus as a Surrogate for Crimean–Congo Hemorrhagic Fever Virus Enables Inactivation Studies at a Low Biosafety Level

Pathogens
Research on highly pathogenic biosafety level 4 (BSL-4) viruses that are classified as Select Agents involves transferring inactivated materials to lower containment levels for further analysis.
Judith Olejnik, Kristina Meier, Jarod N. Herrera, Daniel J. DeStasio, Dylan J. Deeney, Elizabeth Y. Flores, Mitchell R. White, Adam J. Hume, Elke Mühlberger   +8 more
doaj   +1 more source

Arginine as a Synergistic Virucidal Agent

Molecules, 2010
Development of effective and environmentally friendly disinfectants, or virucidal agents, should help prevent the spread of infectious diseases through human contact with contaminated surfaces.
A. Hajime Koyama, Satoshi Ohtake, Tsutomu Arakawa   +2 more
doaj   +1 more source

Upregulation of the Tim-3/galectin-9 pathway of T cell exhaustion in chronic hepatitis B virus infection. [PDF]

, 2012
The S-type lectin galectin-9 binds to the negative regulatory molecule Tim-3 on T cells and induces their apoptotic deletion or functional inactivation.
Cheng, Y, Richard Gilson, Singh, HD, Nebbia Gaia, Dusheiko, G., William Rosenberg, Peppa, D, Cheng, Y., Geoffrey Dusheiko, Cheng Yang, Joanne ChinAleong, ChinAleong, J, Patrick Kennedy, Dusheiko Geoffrey, Maini Mala K., Singh Harsimran D., Pooja Khanna, Maini, MK, Nebbia, G., Khanna, P, Gaia Nebbia (125377), Rosenberg, W, Rosenberg William, Rosenberg, W., Schurich, Anna; id_orcid, Gilson, R, ChinAleong Joanne, Mala K. Maini (125417), Patrick Kennedy (125414), Mala K Maini, Harsimran D Singh, Gilson Richard, ChinAleong, J., Gaia Nebbia, Harsimran D. Singh (125388), Nebbia, G, Khanna Pooja, Kennedy, P., Richard Gilson (125405), Schurich, A, Anna Schurich, Joanne ChinAleong (125409), Geoffrey Dusheiko (125400), Kennedy, P, Singh, H.D., Pooja Khanna (125385), William Rosenberg (14858), Khanna, P., Peppa Dimitra, Gilson, R., Kennedy Patrick, Yang Cheng (125394), Dusheiko, G, Dimitra Peppa, Dimitra Peppa (125379), Yang Cheng, Anna Schurich (125382), Maini, M.K., Peppa, D., Schurich Anna   +59 more
core   +1 more source

RNA virus attenuation by codon pair deoptimisation is an artefact of increases in CpG/UpA dinucleotide frequencies [PDF]

, 2014
Mutating RNA virus genomes to alter codon pair (CP) frequencies and reduce translation efficiency has been advocated as a method to generate safe, attenuated virus vaccines.
David J Evans, Fiona Tulloch, Evans, David John, Tulloch, F., Ryan, M. D., Atkinson, N. J., Ryan, Martin D., Tulloch, Fiona, Martin D Ryan, Simmonds, Peter, Nicky J Atkinson, Atkinson, Nicky J., Peter Simmonds, Evans, David J., Simmonds, P., Evans, D. J.   +15 more
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Efficient production of foot-and-mouth disease virus empty capsids in insect cells following down regulation of 3C protease activity [PDF]

, 2013
Foot-and-mouth disease virus (FMDV) is a significant economically and distributed globally pathogen of Artiodactyla. Current vaccines are chemically inactivated whole virus particles that require large-scale virus growth in strict bio-containment with ...
Owens, Ray, Paramasivam, S, Kotecha, A, Wilsden, G, Parida, Satya, Paton, David, Ren, Junyuan, Al-Khalil, Tara, Belsham, Graham J., Lomonossoff, GP, Li, Yanmin, Belsham, GJ, Loureiro, S, Kotecha, Abhay, Belsham, Graham, Owens, R, Stuart, David I, Lomonossoff, George P., Porta, C, Xu, X, Parida, S, Lomonossoff, George P, Burman, Alison, Paton, D, Jones, IM, Curry, S, Blesham, Graham J., Paramasivam, Saravanan, Xu, Xiaodong, Stuart, DI, Charleston, Bryan, Jackson, T, Charleston, B, Burman, A, Jones, Ian M., Porta, Claudine, Ren, J, Stuart, David I., Fry, E, Stuart, David, Jones, Ian M, Ferris, N, Ferris, Nigel, Loureiro, Silvia, Belsham, Graham J, Curry, Stephen, Jackson, Terry, Al-Khalil, T, Li, Y, Fry, Elizabeth, Wilsden, Ginette   +50 more
core   +1 more source