Results 131 to 140 of about 61,434 (287)

Avian Hepatitis E Virus ORF2 Protein Interacts with Rap1b to Induce Cytoskeleton Rearrangement That Facilitates Virus Internalization. [PDF]

Microbiol Spectr, 2022
Zhang B, Fan M, Fan J, Luo Y, Wang J, Wang Y, Liu B, Sun Y, Zhao Q, Hiscox JA, Nan Y, Zhou EM.   +11 more
europepmc   +1 more source

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Proximity labelling of internalizing influenza A viruses reveals a role for neogenin in virus uptake.

PLoS Pathogens
Influenza A virus (IAV) is a respiratory pathogen of global concern. Entry of most IAVs is mediated by binding of viral hemagglutinin to cellular sialic acid, facilitating virus attachment.
Milagros Sempere Borau, Victor G Gisbert, Josephine von Kempis, Laura M Arroyo-Fernández, Samira Schiefer, David Alsteens, Silke Stertz   +6 more
doaj   +1 more source

Stapled ACE2 peptidomimetics designed to target the SARS-CoV-2 spike protein do not prevent virus internalization. [PDF]

Pept Sci (Hoboken), 2021
Morgan DC, Morris C, Mahindra A, Blair CM, Tejeda G, Herbert I, Turnbull ML, Lieber G, Willett BJ, Logan N, Smith B, Tobin AB, Bhella D, Baillie G, Jamieson AG.   +14 more
europepmc   +1 more source

Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology

Advanced Engineering Materials, EarlyView.
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham, Chenyu Wen, Mohammad Hadi Khaksaran, Won‐Yong Lee, Javier Cruz, Klas Hjort, Dongping Wu, Shi‐Li Zhang   +7 more
wiley   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

Advanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam, Seon Yeong Chae, Young Woo Kwon, Hye Jin Heo, Hye Rin Lee, Ji Hyeok Lee, Dong‐Wook Han, Yun Hak Kim, Suck Won Hong   +8 more
wiley   +1 more source

The role of clathrin and actin in antibody-induced internalization of viral glycoproteins in pseudorabies virus-infected monocytes

, 2001
Addition of pseudorabies virus (PrV)-specific polyclonal immunoglobulins to PrV-infected monocytes induces internalization of plasma membrane-anchored viral glycoproteins and this may interfere with antibody-dependent cell lysis. We investigated the role
Gerlinde R. Van de Walle, Pensaert, Maurice B., Nauwynck, Hans, Maurice B. Pensaert, Van de Walle, Gerlinde R., Hans J. Nauwynck, Van de Walle, Gerlinde, Herman W. Favoreel, Patrick Van Oostveldt, Favoreel, Herman W., Van Oostveldt, Patrick, Favoreel, Herman, Van Oostveldt, Patric, Pensaert, Maurice, Nauwynck, Hans J.   +14 more
core   +1 more source

Computational study of pomegranate peel extract polyphenols as potential inhibitors of SARS-CoV-2 virus internalization. [PDF]

Mol Cell Biochem, 2021
Suručić R, Tubić B, Stojiljković MP, Djuric DM, Travar M, Grabež M, Šavikin K, Škrbić R.   +7 more
europepmc   +1 more source

Exploring an Alternative to mRNA Vaccine Cold Chain Storage: MRNA‐Lipid Nanoparticle Stability When Dried in a Polymer Matrix

Advanced Functional Materials, EarlyView.
The nanostructure, size, and function of mRNA‐loaded lipid nanoparticles are evaluated before drying, within polymer microneedles, and after rehydration. The results reveal the polymer and LNP loadings required to recover nanostructure and preserve the delivery performance in dry‐state formulations.
Brendan P. Dyett, Shahad K. Alsaiari, John L. Daristotle, Timothy A. Forster, Alicia Lau, Dhruv Varshney, Rania Afaneh, Andrew R. Hanna, Charles Sloane, David Mankus, Haitao Yu, Jiali Zhai, DongSoo Yun, Lisa H. Tostanoski, Abigail Lytton‐Jean, Dan H. Barouch, Charlotte E. Conn, Robert Langer, Ana Jaklenec, Calum J. Drummond   +19 more
wiley   +1 more source

Nanoengineered Binetworks in Multifunctional Anionic Block Polymer Mesoblends for Improved Mechanical Properties

Advanced Functional Materials, EarlyView.
Mesoblends consist of a nanostructured polymer into which a second polymer is imbibed with a selective solvent. In this work, a solvent‐templatable pentablock terpolymer possessing a sulfonated midblock is modified with a hydrophilic polymer that is photocrosslinked in situ, yielding a hierarchical binetwork.
Kacie M. Wells, Ivan Kuzmenko, Reza A. Ghiladi, Richard J. Spontak   +3 more
wiley   +1 more source