Results 151 to 160 of about 61,434 (287)

Hydrogel Microtube Drug Carrier for Catheter‐Based Intravascular Therapy

Advanced Healthcare Materials, EarlyView.
This paper proposes hydrogel microtube carriers composed of barium alginate gel, enabling long‐term vascular retention without interrupting blood flow. Intravascular treatments have long been attracting attention for therapeutic efficacy, yet practical delivery methods remained unestablished.
Shota Sato, Hiroki Ohta, Naoki Takakura, Kentaro Kasa, Teppei Komatsu, Dai Kejia, Misato Yoshioka, Hirotaka James Okano, Hiroaki Onoe   +8 more
wiley   +1 more source

Image_4_Direct Interaction Between CD163 N-Terminal Domain and MYH9 C-Terminal Domain Contributes to Porcine Reproductive and Respiratory Syndrome Virus Internalization by Permissive Cells.TIF

, 2019
Porcine reproductive and respiratory syndrome virus (PRRSV) has a highly restricted tropism for cells of the monocyte-macrophage lineage, including porcine alveolar macrophages (PAMs).
En-Min Zhou (750320), Chunyan Wu (318605), Qin Zhao (9559), Gaopeng Hou (4584394), James P. Stewart (7136183), Yuchen Nan (318766), Julian A. Hiscox (2263027), Liangliang Li (1936771), Lu Zhang (50563), Kuokuo Li (7136180), Biyun Xue (4584391), Jingfei Wang (318606)   +11 more
core   +1 more source

Self‐Assembled Skin Equivalents with Monoclonal CRISPR/Cas9‐Modified N/TERT‐1 Keratinocytes: A Cutting‐Edge model for Human Skin and its Diseases

Advanced Healthcare Materials, EarlyView.
Self‐assembled, scaffold‐free full‐thickness skin equivalents with monoclonal, genetically modified N/TERT‐1 keratinocytes represent a novel in vitro model of human skin and skin diseases. The model is highly robust, reproducible, physiologically relevant, and suitable for high‐throughput applications.
Marta Slaufova, Tugay Karakaya, Michela Di Filippo, Thomas Kündig, Hans‐Dietmar Beer   +4 more
wiley   +1 more source

Image_1_Direct Interaction Between CD163 N-Terminal Domain and MYH9 C-Terminal Domain Contributes to Porcine Reproductive and Respiratory Syndrome Virus Internalization by Permissive Cells.TIF

, 2019
Porcine reproductive and respiratory syndrome virus (PRRSV) has a highly restricted tropism for cells of the monocyte-macrophage lineage, including porcine alveolar macrophages (PAMs).
En-Min Zhou (750320), Chunyan Wu (318605), Qin Zhao (9559), Gaopeng Hou (4584394), James P. Stewart (7136183), Yuchen Nan (318766), Julian A. Hiscox (2263027), Liangliang Li (1936771), Lu Zhang (50563), Kuokuo Li (7136180), Biyun Xue (4584391), Jingfei Wang (318606)   +11 more
core   +1 more source

High-Throughput Screening of Antiviral Compounds Using a Recombinant Hepatitis B Virus and Identification of a Possible Infection Inhibitor, Skimmianine

Viruses
We developed a novel hepatitis B virus (HBV) infection-monitoring system using a luminescent, 11-amino acid reporter (HiBiT). We performed high-throughput antiviral screening using this system to identify anti-HBV compounds.
Mika Yoshita, Masaya Funaki, Tetsuro Shimakami, Masaki Kakuya, Kazuhisa Murai, Saiho Sugimoto, Shotaro Kawase, Koji Matsumori, Taro Kawane, Tomoki Nishikawa, Asuka Nakamura, Reo Suzuki, Atsuya Ishida, Narumi Kawasaki, Yuga Sato, Ying-Yi Li, Ariunaa Sumiyadorj, Kouki Nio, Hajime Takatori, Kazunori Kawaguchi, Kazuyuki Kuroki, Takanobu Kato, Masao Honda, Taro Yamashita   +23 more
doaj   +1 more source

Natural Biomaterials for Osteochondral Repair: From Source to Strategy

Advanced Healthcare Materials, EarlyView.
Biological origin‐guided overview of natural biomaterials and therapeutic strategies for osteochondral tissue engineering. The circular diagram categorizes representative materials and strategies into plant/algae‐derived, microbial‐derived, animal‐derived, and human‐derived sources, centered on an osteochondral defect repair model.
Hengyu Liu, Hanyang Zhang, Wenbo Yang, Hao Chen, Jincheng Wang, Fei Chang   +5 more
wiley   +1 more source

Dynamics of transmissible gastroenteritis virus internalization unraveled by single-virus tracking in live cells. [PDF]

FASEB J, 2020
Wang J, Li Y, Wang S, Liu F.
europepmc   +1 more source

Plasmonic Enhancement of Fluorescence and Protein Dynamics in Living Mammalian Cells

Advanced Materials, EarlyView.
This study demonstrates plasmonic enhancement of the function of fluorescent voltage sensing proteins (genetically encoded voltage indicators, (GEVIs), QuasAr6) in live mammalian cells. Coupling to plasmonic nanoparticles does not just increase fluorescence, but influences the protein photocycle, creating a hybrid sensor with its response speed to ...
Marco Locarno, Qiangrui Dong, Marco Post, Xin Meng, Cristiano Glessi, Nynke Marije Hettema, Nidas Brandsma, Sebbe Blokhuizen, Alejandro Castañeda Garcia, Srividya Ganapathy, Thieme Schmidt, Lars van Roemburg, Bing Xu, Chun‐Ting Cho, Liedewij Laan, Miao‐Ping Chien, Daan Brinks   +16 more
wiley   +1 more source

Image_3_Direct Interaction Between CD163 N-Terminal Domain and MYH9 C-Terminal Domain Contributes to Porcine Reproductive and Respiratory Syndrome Virus Internalization by Permissive Cells.TIF

, 2019
Porcine reproductive and respiratory syndrome virus (PRRSV) has a highly restricted tropism for cells of the monocyte-macrophage lineage, including porcine alveolar macrophages (PAMs).
En-Min Zhou (750320), Chunyan Wu (318605), Qin Zhao (9559), Gaopeng Hou (4584394), James P. Stewart (7136183), Yuchen Nan (318766), Julian A. Hiscox (2263027), Liangliang Li (1936771), Lu Zhang (50563), Kuokuo Li (7136180), Biyun Xue (4584391), Jingfei Wang (318606)   +11 more
core   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source