Results 71 to 80 of about 105,888 (295)

Entry by multiple picornaviruses is dependent on a pathway that includes TNK2, WASL, and NCK1 [PDF]

, 2019
Comprehensive knowledge of the host factors required for picornavirus infection would facilitate antiviral development.
Adamovich, Baggen, Bazzone, Bergelson, Berry, Bladt, Brandenburg, Carthy, Coyne, Coyne, Dodding, Donnelly, Edelman, Fernández-Puentes, Franz, Frischknecht, Fujimoto, Galisteo, Galletta, Glaser, Grøvdal, Hackett, Howlin, Huber, Innocenti, Jacobi, Jiang, Jones, Jose, Karlas, Keszei, Kim, König, Liu, Lupberger, Madshus, Madshus, Mahajan, Mahajan, Mahajan, Massaad, Melnick, Nguyen, Oppliger, Peterson, Porotto, Prieto-Echagüe, Prieto-Echagüe, Rohatgi, Rohatgi, Shen, Staring, Stradal, Teo, Wang, Winston, Wolf, Yamauchi, Yokoyama, Yokoyama, Zerbino   +60 more
core   +2 more sources

2018 international meeting of the Global Virus Network

Antiviral Research, 2019
The Global Virus Network (GVN) was established in 2011 to strengthen research and responses to emerging viral causes of human disease and to prepare against new viral pandemics. There are now 45 GVN Centers of Excellence and 7 Affiliate laboratories in 29 countries. The 10th International GVN meeting was held from November 28-30, 2018 in Veyrier du Lac,
Brechot, C, Bryant, J, Endtz, H, Garry, RF, Griffin, DE, Lewi, SR, Mercer, N, Osterhaus, A, Picot, V, Vahlne, A, Verjans, GMGM, Weaver, S   +11 more
openaire   +4 more sources

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The length of vesicular stomatitis virus particles dictates a need for actin assembly during clathrin-dependent endocytosis.

PLoS Pathogens, 2010
Microbial pathogens exploit the clathrin endocytic machinery to enter host cells. Vesicular stomatitis virus (VSV), an enveloped virus with bullet-shaped virions that measure 70 x 200 nm, enters cells by clathrin-dependent endocytosis.
David K Cureton, Ramiro H Massol, Sean P J Whelan, Tomas Kirchhausen   +3 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Preparation and characterization of functionalized heparin-loaded poly-Ɛ-caprolactone fibrous mats to prevent infection with human papillomaviruses. [PDF]

PLoS ONE, 2018
In this study, heparin-loaded poly-ɛ-caprolactone (PCL) fibrous mats were prepared and characterized based on their physical, cytotoxic, thermal, and biological properties.
Daniela Gonzalez, Jorge Ragusa, Peter C Angeletti, Gustavo Larsen   +3 more
doaj   +1 more source

The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls [PDF]

, 2010
Nonviral gene complexes can enter mammalian cells through different endocytic pathways. For efficient optimization of the gene carrier it is important to profile its cellular uptake, because this largely determines its intracellular processing and ...
Dries Vercauteren, Roosmarijn E Vandenbroucke, Arwyn T Jones, Joanna Rejman, Joseph Demeester, Stefaan C De Smedt, Niek N Sanders, Kevin Braeckmans, Wattiaux, Conner, Jones, Grimmer, Rejman, Widera, Maxfield, Mayor, Simons, Parton, Pelkmans, Torgersen, Puri, Singh, Marks, Zuhorn, Glebov, Medina-Kauwe, Khalil, Elouahabi, Midoux, von Gersdorff, Douglas, Wong, Gabrielson, Banks, Ivanov, Wang, Larkin, Rodal, Parton, Nabi, Gonçalves, Nichols, Hinrichsen, Huang, Vanden Broeck, Benmerah, Payne, Damke, Liu, Lamaze, Rejman, Mano, Weyermann, Subtil, Huth, Davis, Yuwen, Sonnichsen   +57 more
core   +3 more sources

The Internal Structure of Influenza Virus

Zeitschrift für Naturforschung B, 1959
Auf Grund von physikalischen, chemischen und serologischen Untersuchungen wird ein Modell der inneren Struktur des Influenza-Virus entwickelt, das in Übereinstimmung mit dem elektronenmikroskopischen Bild ist.
openaire   +2 more sources

2016 International meeting of the Global Virus Network

Antiviral Research, 2017
The Global Virus Network (GVN) was established in 2011 in order to strengthen research and responses to current viral causes of human disease and to prepare against new viral pandemic threats. There are now 38 GVN Centers of Excellence and 6 Affiliate laboratories in 24 countries.
Ramesh Akkina, Heinz Ellerbrok, William Hall, Hideki Hasegawa, Yasushi Kawaguchi, Harold Kleanthous, Edward McSweegan, Natalia Mercer, Victor Romanowski, Hirofumi Sawa, Anders Vahlne   +10 more
openaire   +3 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source