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Recent Issues in Varicella-Zoster Virus Latency [PDF]
Viruses, 2021 Varicella-zoster virus (VZV) is a human herpes virus which causes varicella (chicken pox) as a primary infection, and, following a variable period of latency in neurons in the peripheral ganglia, may reactivate to cause herpes zoster (shingles) as well ...
Peter G. E. Kennedy +2 more
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Models of Herpes Simplex Virus Latency [PDF]
VirusesOur current understanding of HSV latency is based on a variety of clinical observations, and in vivo, ex vivo, and in vitro model systems, each with unique advantages and drawbacks.
Paige N. Canova +2 more
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Molecular Aspects of Varicella-Zoster Virus Latency [PDF]
Viruses, 2018 Primary varicella-zoster virus (VZV) infection causes varicella (chickenpox) and the establishment of a lifelong latent infection in ganglionic neurons. VZV reactivates in about one-third of infected individuals to cause herpes zoster, often accompanied ...
Daniel P. Depledge +2 more
doaj +6 more sources
Virus Latency and the Impact on Plants [PDF]
Frontiers in Microbiology, 2019 Plant viruses are thought to be essentially harmful to the lives of their cultivated crop hosts. In most cases studied, the interaction between viruses and cultivated crop plants negatively affects host morphology and physiology, thereby resulting in ...
Hideki Takahashi +5 more
doaj +6 more sources
Herpes Simplex Virus Latency: The DNA Repair-Centered Pathway [PDF]
Advances in Virology, 2017 Like all herpesviruses, herpes simplex virus 1 (HSV1) is able to produce lytic or latent infections depending on the host cell type. Lytic infections occur in a broad range of cells while latency is highly specific for neurons.
Jay C. Brown
doaj +4 more sources
A Comparison of Pseudorabies Virus Latency to Other α-Herpesvirinae Subfamily Members [PDF]
Viruses, 2022 Pseudorabies virus (PRV), the causative agent of Aujeszky’s disease, is one of the most important infectious pathogens threatening the global pig industry.
Jing Chen +7 more
doaj +2 more sources
Identification of Host Biomarkers of Epstein-Barr Virus Latency IIb and Latency III [PDF]
mBio, 2019 Deciphering the molecular pathogenesis of virally induced cancers is challenging due, in part, to the heterogeneity of both viral gene expression and host gene expression. Epstein-Barr virus (EBV) is a ubiquitous herpesvirus prevalent in B-cell lymphomas
Joshua E. Messinger +4 more
doaj +2 more sources
HSV-1 genome subnuclear positioning and associations with host-cell PML-NBs and centromeres regulate LAT locus transcription during latency in neurons. [PDF]
, 2012 Major human pathologies are caused by nuclear replicative viruses establishing life-long latent infection in their host. During latency the genomes of these viruses are intimately interacting with the cell nucleus environment.
Catez, Frédéric +8 more
core +14 more sources
Viruses, 2022 Herpes simplex virus 1 and 2 infections cause high unmet disease burdens worldwide. Mainly HSV-2 causes persistent sexually transmitted disease, fatal neonatal disease and increased transmission of HIV/AIDS.
Ursula A. Gompels +5 more
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RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA [PDF]
Open Biology, 2015 MicroRNAs (miRNAs) integrate with Argonaut (Ago) to create the RNA-induced silencing complex, and regulate gene expression by silencing target mRNAs. RNA editing of miRNA may affect miRNA processing, assembly of the Ago complex and target mRNA binding ...
Yalei Cui +2 more
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