Results 41 to 50 of about 76,448 (148)

Latency of Human Measles Virus in Hamster Cells [PDF]

open access: yesJournal of Virology, 1972
A latent system employing measles virus (Schwarz strain) was developed in hamster embryo fibroblasts (HEF). Measles virus-specific antigen was detected by immunofluorescence in 30 to 50% of HEF cells, and these cells released infectious virus when co-cultivated with a susceptible monkey cell line, BSC-1 cells.
P, Knight, R, Duff, F, Rapp
openaire   +2 more sources

Towards an Understanding of the Herpes Simplex Virus Type 1 Latency-Reactivation Cycle

open access: yesInterdisciplinary Perspectives on Infectious Diseases, 2010
Infection by herpes simplex virus type 1 (HSV-1) can cause clinical symptoms in the peripheral and central nervous system. Recurrent ocular shedding can lead to corneal scarring and vision loss making HSV-1 a leading cause of corneal blindness due to an ...
Guey-Chuen Perng, Clinton Jones
doaj   +1 more source

Human cytomegalovirus UL138 interaction with USP1 activates STAT1 in infection.

open access: yesPLoS Pathogens, 2023
Innate immune responses are crucial for limiting virus infection. However, viruses often hijack our best defenses for viral objectives. Human Cytomegalovirus (HCMV) is a beta herpesvirus which establishes a life-long latent infection.
Kristen Zarrella   +9 more
doaj   +1 more source

Key Issues in Varicella-Zoster Virus Latency [PDF]

open access: yesJournal of Neurovirology, 2002
The molecular mechanisms by which varicella-zoster virus (VZV) causes a latent infection in human trigeminal and spinal ganglia are not well understood. It is known that VZV establishes latency in ganglia following the primary infection causing varicella (chickenpox), and that the virus may reactivate after years of dormancy to produce herpes zoster ...
openaire   +2 more sources

Presence of CD80 and Absence of LAT in Modulating Cellular Infiltration and HSV-1 Latency

open access: yesViruses
CD80 is the best-known costimulatory molecule for effective T cell functions. Many different reports have summarized the role of CD80 in HSV-1 and its functions in maintaining adaptive immunity, which is the main player in causing herpes stromal ...
Ujjaldeep Jaggi, Homayon Ghiasi
doaj   +1 more source

The ND10 Complex Represses Lytic Human Herpesvirus 6A Replication and Promotes Silencing of the Viral Genome

open access: yesViruses, 2018
Human herpesvirus 6A (HHV-6A) replicates in peripheral blood mononuclear cells (PBMCs) and various T-cell lines in vitro. Intriguingly, the virus can also establish latency in these cells, but it remains unknown what influences the decision between lytic
Anirban Sanyal   +5 more
doaj   +1 more source

THE MOLECULAR MECHANISMS OF EPSTEINBARR VIRUS PERSISTENCE IN THE HUMAN ORGANISM [PDF]

open access: yesAnnals of Mechnikov's Institute, 2014
This review describes advances in molecular aspects of EBV infection and disease. We discuss the spectrum of clinical illness due to EBV persistent infection.
Volyanskiy A.Yu.   +8 more
doaj  

Acute HSV-1 Ocular Infection Is Impaired in KLF15 Knockout Mice but Stress-Induced Reactivation from Latency Is Prolonged in Male KLF15 Knockout Mice

open access: yesPathogens
Acute human alpha-herpesvirus 1 (HSV-1) infection culminates in a latent infection of neurons in trigeminal ganglia (TG) and the central nervous system.
Kelly S. Harrison, Clinton Jones
doaj   +1 more source

Herpes simplex virus type-1 latency inhibits dendritic growth in sympathetic neurons

open access: yesNeurobiology of Disease, 2006
Herpes simplex virus type-1 (HSV-1) initially infects mucoepithelial tissues of the orofacial region, the eye and to a lesser extent the genitalia. Subsequently, the virus is retrogradely transported through the axons of the sensory and sympathetic ...
Mohamed A. Hamza   +2 more
doaj   +1 more source

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