Results 61 to 70 of about 76,448 (148)

A Quadruple Gene-Deleted Live BoHV-1 Subunit RVFV Vaccine Vector Reactivates from Latency and Replicates in the TG Neurons of Calves but Is Not Transported to and Shed from Nasal Mucosa

Viruses
Bovine herpesvirus type 1 (BoHV-1) establishes lifelong latency in trigeminal ganglionic (TG) neurons following intranasal and ocular infection in cattle. Periodically, the latent virus reactivates in the TG due to stress and is transported anterogradely
Selvaraj Pavulraj, Rhett W. Stout, Daniel B. Paulsen, Shafiqul I. Chowdhury   +3 more
doaj   +1 more source

DLK-Dependent Biphasic Reactivation of Herpes Simplex Virus Latency Established in the Absence of Antivirals. [PDF]

J Virol, 2022
Dochnal S, Merchant HY, Schinlever AR, Babnis A, Depledge DP, Wilson AC, Cliffe AR.   +6 more
europepmc   +1 more source

Retraction: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui et al.

Open Biology, 2023
doaj   +1 more source

The anti-apoptotic function of HSV-1 LAT in neuronal cell cultures but not its function during reactivation correlates with expression of two small non-coding RNAs, sncRNA1&2.

PLoS Pathogens
Multiple functions are associated with HSV-1 latency associated transcript (LAT), including establishment of latency, virus reactivation, and antiapoptotic activity.
Jay J Oh, Ujjaldeep Jaggi, Kati Tormanen, Shaohui Wang, Satoshi Hirose, Homayon Ghiasi   +5 more
doaj   +1 more source

Marek’s disease virus-encoded microRNA-M6-5p facilitates viral latent infection by targeting histone demethylase KDM2B

Journal of Virology
Marek’s disease virus (MDV), a highly contagious and oncogenic avian alphaherpesvirus, establishes a latent infection primarily in CD4+ T cells. Latent infections are necessary for both persistent lifelong MDV infection and viral tumorigenesis. MicroRNAs
Linyi Zhou, Runan Zhu, Bo Jiang, Jing Cheng, Wenxiao Liu, Yongxiu Yao, Yongqing Li   +6 more
doaj   +1 more source

ΔNp63α promotes Epstein-Barr virus latency in undifferentiated epithelial cells. [PDF]

PLoS Pathog, 2021
Van Sciver N, Ohashi M, Nawandar DM, Pauly NP, Lee D, Makielski KR, Bristol JA, Tsao SW, Lambert PF, Johannsen EC, Kenney SC.   +10 more
europepmc   +1 more source

Modular Approaches to Understand the Immunobiology of Human Immunodeficiency Virus Latency. [PDF]

Viral Immunol, 2021
Wolf G, Singh NJ.
europepmc   +1 more source

Role of the cellular factor CTCF in the regulation of bovine leukemia virus latency and three-dimensional chromatin organization. [PDF]

Nucleic Acids Res, 2022
Bellefroid M, Rodari A, Galais M, Krijger PHL, Tjalsma SJD, Nestola L, Plant E, Vos ESM, Cristinelli S, Van Driessche B, Vanhulle C, Ait-Ammar A, Burny A, Ciuffi A, de Laat W, Van Lint C.   +15 more
europepmc   +1 more source

Mathematical modeling and mechanisms of HIV latency for personalized anti latency therapies

npj Systems Biology and Applications
Combination antiretroviral therapy controls human immunodeficiency virus-1 (HIV) but cannot eradicate latent proviruses in immune cells, which reactivate upon treatment interruption.
Gianmarco Rasi, Elena Emili, Jessica M. Conway, Nicola Cotugno, Paolo Palma   +4 more
doaj   +1 more source

Vaccination with a Replication-Dead Murine Gammaherpesvirus Lacking Viral Pathogenesis Genes Inhibits WT Virus Infection

Viruses
Gammaherpesviruses are oncogenic pathogens that establish lifelong infections. There are no FDA-approved vaccines against Epstein–Barr virus or Kaposi sarcoma herpesvirus.
Dipanwita Mitra, Darby G. Oldenburg, J. Craig Forrest, Laurie T. Krug   +3 more
doaj   +1 more source