Results 131 to 140 of about 760,800 (362)

PP 1.28 – 00156 The HIV-1 antisense RNA Ast promotes viral latency via epigenetic silencing of the proviral 5′LTR and is expressed in latently infected cells from ART-suppressed donors

Journal of Virus Eradication, 2022
F. Romerio, R. Li, R. Sklutuis, J. Groebner, M. Kearney   +4 more
doaj   +1 more source

How to recover from a bad start: adaptation of HIV-1 transcription start site mutants during serial passaging in culture

Journal of Virology
HIV-1 uses neighboring sequences as transcription start sites and generates multiple unspliced transcripts, including two major transcripts with three guanosines (3G) or one guanosine (1G) at the 5′ end. Although only differing by 2-nt, 3G RNA and 1G RNA
Olga A. Nikolaitchik, Akhil Chameettachal, Saiful Islam, Zetao Cheng, Krista Delviks-Frankenberry, Brandon F. Keele, Vinay K. Pathak, Wei-Shau Hu   +7 more
doaj   +1 more source

Plant virus replication and movement

Virology, 2015
Replication and intercellular spread of viruses depend on host mechanisms supporting the formation, transport and turnover of functional complexes between viral genomes, virus-encoded products and cellular factors. To enhance these processes, viruses assemble and replicate in membrane-associated complexes that may develop into "virus factories" or ...
Heinlein Manfred, Heinlein Manfred
openaire   +4 more sources

Inactivating SARS‐CoV‐2 Virus with MOF‐Composites as Smart Face Masks

Advanced Functional Materials, EarlyView.
In situ preparation and functionalization of MOF@Cotton fabrics as smart face masks for the immobilization of proteins and inactivation viruses, such as SARS‐CoV‐2. Abstract The significant impact of the SARS‐CoV‐2 (COVID‐19) pandemic outbreak on people's lives has highlighted the urgent need for effective personal protective equipment.
Romy Ettlinger, Aamod V. Desai, Hau Lam Jody Cheong, Louise L. Major, Terry K. Smith, Aaron B. Naden, Jane Hilton, Catherine S. Adamson, A. Robert Armstrong, Russell E. Morris   +9 more
wiley   +1 more source

Dengue virus binding and replication by platelets [PDF]

, 2015
Ayo Yila Simon, Michael R. Sutherland, Edward L.G. Pryzdial   +2 more
openalex   +1 more source

G-quadruplexes control hepatitis B virus replication by promoting cccDNA transcription and phase separation in hepatocytes [PDF]

, 2023
Guillaume Giraud, Mélanie Rodà, Pélagie Huchon, Maud Michelet, Sarah Maadadi, Daniel Jutzi, Roland Montserret, Marc‐David Ruepp, Romain Parent, Christophe Combet, Fabien Zoulim, Barbara Testoni   +11 more
openalex   +1 more source

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Heteroaryldihydropyrimidine (HAP) and Sulfamoylbenzamide (SBA) Inhibit Hepatitis B Virus Replication by Different Molecular Mechanisms [PDF]

, 2017
Zheng Zhou, Taishan Hu, Xue Zhou, Steffen Wildum, Fernando García-Alcalde, Zhiheng Xu, Daitze Wu, Yi Mao, Xiao‐Jun Tian, Yuan Zhou, Fang Shen, Zhisen Zhang, Guozhi Tang, Isabel Nájera, Guang Yang, Hong C. Shen, John A. T. Young, Na Qin   +17 more
openalex   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

RNA therapy is shining for genetic diseases

Molecular Therapy: Nucleic Acids, 2023
Zhi-Ming Zheng
doaj   +1 more source