Results 231 to 240 of about 675,632 (363)

Nuclear Translocation of S100A9 Triggers Senescence of Human Amnion Fibroblasts by De‐Repressing LINE1 Via Heterochromatin Erosion at Parturition

open access: yesAdvanced Science, EarlyView.
This study shows that the classical secretory protein S100 calcium‐binding protein A9 (S100A9) can translocate to the nucleus upon de‐phosphorylation at Thr 113 in human amnion fibroblasts at parturition, where S100A9 induces heterochromatin erosion through segregation of the heterochromatin maintenance protein, resulting inLong Interspersed Nuclear ...
Fan Zhang   +8 more
wiley   +1 more source

USP1 inhibits influenza A and B virus replication in MDCK cells by mediating RIG-I deubiquitination. [PDF]

open access: yesCell Mol Life Sci
Liao Y   +11 more
europepmc   +1 more source

Inhibiting the Histone Demethylase Kdm4a Restrains Cardiac Fibrosis After Myocardial Infarction by Promoting Autophagy in Premature Senescent Fibroblasts

open access: yesAdvanced Science, EarlyView.
Kdm4a downregulation restrains excessive cardiac interstitial fibrosis and remodeling by depressing the premature senescence of fibroblasts in the advanced stage after MI but does not affect early ventricular rupture. It verified that Kdm4a downregulation promotes autophagy in premature senescent fibroblasts by increasing the H3K9m3 modification of the
Ming Jin   +15 more
wiley   +1 more source

Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

open access: yesAdvanced Science, EarlyView.
Schematic diagram illustrating the mechanism of shortened lifespan in Thy 1‐C/EBPβ transgenic mice and intervention strategies. Briefly, C/EBPβ/AEP escalation in the aging brain triggers NAMPT fragmentation and NAD+ depletion. Knockout of AEP from Thy 1‐C/EBPβ Tg/Tg mice ameliorates cognitive impairments and elongates the lifespan.
Bowei Li   +8 more
wiley   +1 more source

Intestinal influenza: Replication and characterization of influenza viruses in ducks

open access: green, 1978
Robert G. Webster   +4 more
openalex   +1 more source

Temporal and spatial characterization of keratinocytes supporting orf virus replication. [PDF]

open access: yesFront Cell Infect Microbiol
Seung BJ   +3 more
europepmc   +1 more source

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