Results 231 to 240 of about 760,800 (362)

Quantitative Virus-Associated RNA Detection to Monitor Oncolytic Adenovirus Replication [PDF]

Tereza Brachtlova, Jing Li, Ida H. van der Meulen‐Muileman, Femke Sluiter, Willem von Meijenfeldt, Isabella Witte, Sanne Massaar, Ruben van den Oever, Jeroen de Vrij, Victor W. van Beusechem   +9 more
openalex   +1 more source

The herpes simplex virus immediate-early protein, ICP4, is required to potentiate replication of human immunodeficiency virus in CD4+ lymphocytes [PDF]

, 1989
Mary Albrecht, Neal A. DeLuca, Randal A. Byrn, Priscilla A. Schaffer, Scott M. Hammer   +4 more
openalex   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

VPS34-mediated autophagosome-lysosome fusion facilitates classical swine fever virus replication. [PDF]

J Virol
Li Y-h, Cheng Y, Zhao B-q, Chen J-x, Li M-z, Zhong L-h, Dai Q, Bi X-q, Chen J, Zhou B.   +9 more
europepmc   +1 more source

Epstein-Barr nuclear antigen 1 mediates a DNA loop within the latent replication origin of Epstein-Barr virus.

, 1991
Lori Frappier, Mike O’Donnell
openalex   +2 more sources

Neuroinflammation and Virus Replication in the Spinal Cord of Simian Immunodeficiency Virus–Infected Macaques [PDF]

, 2014
Lisa M. Mangus, Jamie L. Dorsey, Victoria A. Laast, Peter Hauer, Suzanne E. Queen, Robert J. Adams, Justin C. McArthur, Joseph L. Mankowski   +7 more
openalex   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

Advanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann, Theresa M. Wierschin, Stefanie Kretschmer, Banaja P. Dash, Aaron Held, Andrea Salzinger, Kevin Peikert, Anže Karlek, Hannes Glaß, Dajana Großmann, René Günther, Susanne Petri, Annekathrin Rödiger, David Brenner, Francisco Pan‐Montojo, Eleonora Aronica, Markus Kipp, Vitaly Zimyanin, Jared Sterneckert, Torsten Grehl, Noah D. Seebacher, Tobias M. Böckers, Alberto Catanese, Brian J. Wainger, Patrick Oeckl, Min Ae Lee‐Kirsch, Andreas Hermann   +26 more
wiley   +1 more source

Thapsigargin suppresses porcine hemagglutinating encephalomyelitis virus replication by disrupting host energy metabolism. [PDF]

Virol Sin
Jia Q, Li Z, Yu Y, Cao Z, Qiu R, Zhang J, He W, Shi J.   +7 more
europepmc   +1 more source

HA Protein acetylation modulates replication, pathogenicity, and immunogenicity of influenza virus and facilitates live-attenuated vaccine design

Mingqing Wu, Meimei Wang, Xinyu Zeng, Kehui Zhang, Minghan Wang, Guanlong Xu, Zhaofei Wang, Yuqiang Cheng, Heng’an Wang, Yaxian Yan, Tao Sun, Jingjiao Ma   +11 more
openalex   +1 more source

Pre‐Encoded IFN‐I Sensitivity Exacerbates Memory T Cell Senescence in Solid Tumors

Advanced Science, EarlyView.
Type I interferon (IFN‐I) signaling promotes p21‐dependent cell cycle arrest in senescent tumor‐specific memory T cells, resulting in poor proliferative responses and solid tumor regression during cancer vaccination. Conversely, IFNα/β receptor blockade reinvigorates T cell proliferation to regress solid tumors and is more effective with increasing ...
Andrew Nguyen, Scott R Walsh, Li Deng, Lan Chen, Yonghong Wan   +4 more
wiley   +1 more source