Through metabolomic and transcriptomic analyses, a glutamine‐enriched, immunosuppressive microenvironment is identified in cervical squamous cell carcinoma (CSCC), highlighting the glutamine transporter SLC25A22 as a key regulator of glutamine metabolism, immune checkpoint activation, and CD8+ T‐cell cytotoxicity.
Tingting Ren+7 more
wiley +1 more source
Effective inhibition of dengue virus replication using 3'UTR-targeted Vivo-Morpholinos. [PDF]
Niu M+11 more
europepmc +1 more source
Structure and Antigenicity of Kaposi's Sarcoma‐Associated Herpesvirus Glycoprotein B
Kaposi's sarcoma‐associated herpesvirus (KSHV) causes severe cancers without effective treatments. This study presents an atomic model of KSHV's critical infection protein, gB, revealing a unique structure shared with related herpesviruses like Epstein‐Barr virus (EBV). The structural similarity highlights vulnerable targets for antibodies, guiding the
Xin‐Yan Fang+8 more
wiley +1 more source
Persistent Infections in Tick Cell Lines: The Role of Viral-Derived DNA Forms in Hazara Virus Replication and Cellular Survival. [PDF]
Dias E+5 more
europepmc +1 more source
In situ fate of Chikungunya virus replication organelles. [PDF]
Girard J+12 more
europepmc +1 more source
METTL3 depletion blocks vesicular stomatitis virus replication in pancreatic cancer cells through the establishment of an intrinsic antiviral state. [PDF]
Catacalos-Goad C+4 more
europepmc +1 more source
Eukaryotic RNA binding protein hnRNPH1 suppresses influenza A virus replication through interaction with virus NS1 protein. [PDF]
Wang J+5 more
europepmc +1 more source
Heterogeneous Ribonucleoprotein K Is a Host Regulatory Factor of Chikungunya Virus Replication in Astrocytes. [PDF]
Pieterse L+3 more
europepmc +1 more source
Positive-strand RNA virus replication organelles at a glance.
Stancheva VG, Sanyal S.
europepmc +1 more source