Results 271 to 280 of about 760,800 (362)

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source

Chlorinated biscoumarins inhibit chikungunya virus replication in cell-based and animal models. [PDF]

Emerg Microbes Infect
Orji CN, Loeanurit N, Pham VC, Phan TH, Hengphasatporn K, Shigeta Y, Putri AD, Lello LS, Merits A, Wacharachaisurapol N, Eiamart W, Wittayalertpanya S, Khotavivattana T, Chavasiri W, Boonyasuppayakorn S.   +14 more
europepmc   +1 more source

Metformin Impairs Breast Cancer Growth through the Inhibition of PRMT6

Advanced Science, EarlyView.
Metformin has a biological activity against breast cancer. However, it is largely unknown about its precise therapeutic targets. Here, histone arginine methyltransferase PRMT6 is identified as a new anti‐cancer target for metformin. Metformin directly binds PRMT6 and inhibits its ability to catalyze histone H3R2 asymmetric dimethylation (H3R2me2a ...
Yinsheng Wu, Xinlin Xu, Yue Tong, Min Wang, Feng Ge, Min Wu, Yunlong Wang, Gang Chen, Xilan Yu, Shanshan Li   +9 more
wiley   +1 more source

Negative regulation of reassortant canine influenza virus replication and key site identification in porcine and ferret bronchial epithelial cell lines. [PDF]

Virulence
Guo J, Jung B, Yoon SW, Liu Y, Feng Z, Yeom M, Na W, Xu Q, Lim JW, Pang M, Hao F, Chen R, Song D, Xie X.   +13 more
europepmc   +1 more source

RNA virus replication

Journal of Clinical Virology, 2000
openaire   +1 more source

HPD is an m6A Methyltransferase that Protects Colorectal Cancer Cells from Ferroptotic Cell Death by m6A Methylating SLC7A11/GPX4

Advanced Science, EarlyView.
This study reveals that the tyrosine metabolic enzyme HPD functions as a previously uncharacterized, METTL3‐independent m6A methyltransferase. It promotes colorectal tumor progression by coordinately regulating the SLC7A11/GPX4 axis to suppress ferroptosis.
Jiyan Wang, Xintong Dai, Huanle Liu, Saiwei Hua, Hongkai Chang, Huanran Sun, Mingming Sun, Huifang Zhao, Kemin Ni, Fei Xie, Yaya Qiao, Qingle Gao, Chenxi Yu, Qijun Zhang, Jianshuang Guo, Chunze Zhang, Shuai Zhang, Changliang Shan   +17 more
wiley   +1 more source

An SRR1 domain-containing protein is required for efficient Orsay virus replication in <i>Caenorhabditis elegans</i>. [PDF]

J Virol
Fujii C, Wang D.
europepmc   +1 more source

Table 9_The crucial role of mitochondrial/chloroplast-related genes in viral genome replication and host defense: integrative systems biology analysis in plant-virus interaction.xlsx

Amir Ghaffar Shahriari (15998219), Aminallah Tahmasebi (6749633), Mohamad Hamed Ghodoum Parizipour (21163886), Zahra Soltani (2898647), Ahmad Tahmasebi (561590), Muhammad Shafiq Shahid (12533092)   +5 more
openalex   +1 more source

Venom Components of Iranian Scorpion Hemiscorpius lepturus Inhibit the Growth and Replication of Human Immunodeficiency Virus 1 (HIV-1).

, 2016
Rezvan Zabihollahi, Kamran Pooshang Bagheri, Zohreh Keshavarz, Fatemeh Motevalli, Golnaz Bahramali, Seyed Davar Siadat, Seyed Bahman Momen, Delavar Shahbazzadeh, Mohammad Reza Aghasadeghi   +8 more
openalex   +1 more source

Extracellular Vesicle‐Delivered tRF‐His‐GTG‐1 Reprograms Neutrophil Lipophagy and Triggers Inflammation in COVID‐19

Advanced Science, EarlyView.
This study identifies platelet‐derived extracellular vesicles as key immunometabolic regulators in COVID‐19. The delivery of tRF‐His‐GTG‐1 to neutrophils activates TLR8mTOR signaling, disrupts lipophagy, and amplifies NET‐mediated inflammation. Importantly, targeting this axis restores neutrophil homeostasis, offering a potential therapeutic strategy ...
Tsai‐Ling Liao, Po‐Yu Liu, Yi‐Ming Chen, Kuo‐Tung Tang, Hung‐Jen Liu, Der‐Yuan Chen   +5 more
wiley   +1 more source