Results 281 to 290 of about 760,800 (362)

Luteolin Inhibits Bovine Viral Diarrhea Virus Replication by Disrupting Viral Internalization and Replication and Interfering with the NF-κB/STAT3-NLRP3 Inflammasome Pathway. [PDF]

Vet Sci
Cai D, Liu Q, Shen Z, Tian B, Gao J, Lin Y, Ma L, Wang Y, Ma X.   +8 more
europepmc   +1 more source

ZNRD2 Mediated Nucleoprotein Aggregation Impairs Respiratory Syncytial Virus Replication

Advanced Science, EarlyView.
During RSV infection, nucleoprotein (N) forms RNA‐bound oligomers. The host protein ZNRD2 binds to these oligomers, promoting their transition into insoluble aggregates. These aggregates simultaneously sequester functional N to restrict viral production and disrupt chaperonin assembly quality control by interfering with ZNRD2's role as an adaptor ...
Haiwu Zhou, Mingbin He, Jinhong Du, Cong Liu, Weiwei Wang, Yuewen Han, Zhifei Li, Yali Qin, Mingzhou Chen   +8 more
wiley   +1 more source

A trans-activating transduction peptide fused nanobody targeting viral nonstructural protein NS4B inhibits bovine viral diarrhea virus replication. [PDF]

Front Immunol
Zhao B, Lv Z, Fan W, Zhang Y, Wei S, Fang J, Huang N, Chen X, Wang L, Qi X.   +9 more
europepmc   +1 more source

Exclusive Breastfeeding Drives AMPK‐Dependent Thermogenic Memory in BAT and Promotes Long‐Term Metabolic Benefits in Offspring

Advanced Science, EarlyView.
Exclusive breastfeeding establishes a thermogenic memory in brown adipose tissue by activating the HIF1AN/AMPK/α‐ketoglutarate axis via milk‐derived extracellular vesicles enriched in miR‐125a‐5p. This programming preserves metabolic health, while αKG supplementation restores BAT function under mixed feeding, offering strategies to mitigate the ...
Ningxi Wu, Anwen Yin, Xiang Yu, Mingxin Wang, Jiahui Zhang, Kerong Liu, Yutong Hou, Minkai Cao, Yiting Zhang, Xiaoxiao Zhang, Yao Gao, Xirong Guo, Le Zhang, Yun Li   +13 more
wiley   +1 more source

Metabolic Imprint of Poliovirus on Glioblastoma Cells and Its Role in Virus Replication and Cytopathic Activity. [PDF]

Int J Mol Sci
Zenov MA, Yanvarev DV, Ivanova ON, Denisova EA, Golikov MV, Fedulov AP, Frykin RI, Sarkisova VA, Goldstein DA, Chumakov PM, Lipatova AV, Ivanov AV.   +11 more
europepmc   +1 more source

Table 12_The DEAD-box RNA helicase 27 negatively regulates the replication of porcine reproductive and respiratory syndrome virus by mediating GP2a autophagy degradation and inducing interferon-β production.xlsx

Binghua Chen (236328), Yunyan Luo (12185358), Yongjie Chen (269938), Jingxing Wang (3079734), Jiecong Yan (21528902), Zhan He (3112443), Fangfang Li (1972918), Chunhe Guo (5549639)   +7 more
openalex   +1 more source

Replicative Level of Hepatitis C Virus(HCV) in Chronic Hepatitis C.

, 1993
Norio Hayashi, Takenobu Kamada
openalex   +2 more sources

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

Bisbenzylisoquinoline alkaloids inhibit influenza virus replication by disrupting endosomal acidification. [PDF]

Virol J
Li B, Qiao L, Li X, Yang G, Wang K, Wang H, Wu S, Yan H, Jiang J, Li Y.   +9 more
europepmc   +1 more source

Investigating Marine Natural Products as Potential Antivirals of Mpox Virus Replication by Targeting Thymidylate Kinase

Manikandan Jayaraman, Vijayakumar Gosu, Maharaja Muthuvairam Subbulakshmi, Rajalakshmi Kumar, Donghyun Shin, Jeyaraman Jeyakanthan   +5 more
openalex   +1 more source