Sequential packaging of RNA genomic segments during the assembly of Bluetongue virus. [PDF]
, 2014 Bluetongue virus (BTV), a member of the Orbivirus genus within the Reoviridae family, has a genome of 10 double-stranded RNA segments, with three distinct size classes.
Roy, Polly +3 more
core +1 more source
Cholesterol dependence of collagen and echovirus 1 trafficking along the novel α2β1 integrin internalization pathway. [PDF]
PLoS ONE, 2013 We have previously shown that soluble collagen and a human pathogen, echovirus 1 (EV1) cluster α2β1 integrin on the plasma membrane and cause their internalization into cytoplasmic endosomes.
Elina Siljamäki +7 more
doaj +1 more source
Antirhinovirus compound 44,081 R.P. inhibits virus uncoating [PDF]
Antimicrobial Agents and Chemotherapy, 1986 44,081 R.P., or 2-[(1,5,10,10a-tetrahydro-3H-thiazolo[3,4-b]isoquinolin- 3-ylidine)amino]-4-thiazole acetic acid, is a compound which selectively inhibits rhinovirus in cell cultures. The compound, which was unable to inactivate infectivity of virions, appeared to act prior to RNA and protein synthesis without affecting adsorption or penetration of ...
B, Alarcon +3 more
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Vaccinia Virus Infection Requires Maturation of Macropinosomes. [PDF]
, 2015 The prototypic poxvirus, vaccinia virus (VACV), occurs in two infectious forms, mature virions (MVs) and extracellular virions (EVs). Both enter HeLa cells by inducing macropinocytic uptake.
Mercer, Jason +13 more
core +1 more source
Cellular receptors for enterovirus A71
Journal of Biomedical Science, 2020 Enterovirus 71 (EV-A71) is one of the major causative agents of hand, foot, and mouth disease. EV-A71 infection is sometimes associated with severe neurological diseases such as acute encephalitis, acute flaccid paralysis, and cardiopulmonary failure ...
Kyousuke Kobayashi, Satoshi Koike
doaj +1 more source
pH-Controlled Two-Step Uncoating of Influenza Virus [PDF]
Biophysical Journal, 2014 Upon endocytosis in its cellular host, influenza A virus transits via early to late endosomes. To efficiently release its genome, the composite viral shell must undergo significant structural rearrangement, but the exact sequence of events leading to viral uncoating remains largely speculative.
Li, Sai +7 more
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Adsorption, Penetration and Uncoating of Herpes Simplex Virus
Journal of General Virology, 1968 Summary The interaction of herpes virus particles with BSC1 cells was studied with purified virus particles labelled in the DNA and coat proteins. Intact virions adsorbed to the cell within 3 hr, a process not affected by inhibitors of nucleic acid and protein synthesis.
E, Hochberg, Y, Becker
openaire +2 more sources
RNA‐centric world of retroviruses: unravelling the molecular strategies of genomic RNA packaging
Biological Reviews, EarlyView.ABSTRACT Retroviruses constitute a unique group of RNA viruses that have profoundly influenced both evolutionary trajectories and biomedical research. Their ability to reverse transcribe and integrate into host genomes has shaped genomic architecture across species and contributed to our understanding of oncogenes, gene regulation, and RNA biology ...
Mohammad Abdullah Jehad +5 more
wiley +1 more source
RNA packaging and uncoating in simple single-stranded RNA viruses [PDF]
, 2012 Simple (non-enveloped) small, positive-sense single-stranded RNA viruses infect hosts from all kingdoms of life. However, their assembly and uncoating processes remain poorly understood. For turnip crinkle virus (TCV), 3D reconstructions by cryoelectron
Bakker, Saskia
core
Entry pathways of herpes simplex virus type 1 into human keratinocytes are dynamin- and cholesterol-dependent [PDF]
, 2011 Herpes simplex virus type 1 (HSV-1) can enter cells via endocytic pathways or direct fusion at the plasma membrane depending on the cell line and receptor(s).
Mei-Ju Hsu +16 more
core +1 more source