Results 71 to 80 of about 13,089 (196)

Rapid generation of replication-deficient monovalent and multivalent vaccines for bluetongue virus: protection against virulent virus challenge in cattle and sheep.

, 2013
Since 1998, 9 of the 26 serotypes of bluetongue virus (BTV) have spread throughout Europe, and serotype 8 has suddenly emerged in northern Europe, causing considerable economic losses, direct (mortality and morbidity) but also indirect, due to ...
Hoffmann, B., C.C.P. Celma, Wernike, Kerstin, Eschbaumer, M., Wernike, K., De Clercq, K., van Rijn, Piet A, Haegeman, Andy, Beer, M., B. Hoffmann, A. Haegeman, P.A. van Rijn, van Rijn, P.A., Clercq, K., De, Celma, C.C.P., Eschbaumer, Michael, P. Roy, Boyce, Mark, Roy, Polly, M. Boyce, Roy, P., Hoffmann, Bernd, De Clercq, Kris, Rijn, P.A., van, M. Beer, Boyce, M., M. Eschbaumer, Celma, Cristina CP, K. De Clercq, Beer, Martin, K. Wernike   +30 more
core   +1 more source

The E3 Ubiquitin Ligase Mind Bomb 1 Controls Adenovirus Genome Release at the Nuclear Pore Complex

Cell Reports, 2019
Summary: Adenoviruses (AdVs) cause respiratory, ocular, and gastrointestinal tract infection and inflammation in immunocompetent people and life-threatening disease upon immunosuppression.
Michael Bauer, Justin W. Flatt, Daria Seiler, Bettina Cardel, Mario Emmenlauer, Karin Boucke, Maarit Suomalainen, Silvio Hemmi, Urs F. Greber   +8 more
doaj   +1 more source

Tobamoviruses CP Proteins Hijack Light‐Induced Protein (NbLIP1) to Promote Viral Replication by Facilitating VRO Formation

Plant Biotechnology Journal, Volume 24, Issue 4, Page 2419-2438, April 2026.
ABSTRACT Tobamoviruses establish viral replication organelles (VROs) on the host endoplasmic reticulum (ER) for their replication, a process demanding substantial different types of lipids. However, how viruses efficiently transfer these lipids from other compartments like chloroplasts remains incompletely understood.
Haoyu Chen, Mingjie Wu, Xiao Guo, Hongmei Xu, Chenwei Feng, Duxuan Liu, Jing Hua, Yanhong Hua, Zhen He, Peter Moffett, Kun Zhang   +10 more
wiley   +1 more source

Centrosomal latency of incoming foamy viruses in resting cells.

PLoS Pathogens, 2007
Completion of early stages of retrovirus infection depends on the cell cycle. While gammaretroviruses require mitosis for proviral integration, lentiviruses are able to replicate in post-mitotic non-dividing cells.
Jacqueline Lehmann-Che, Noémie Renault, Marie Lou Giron, Philippe Roingeard, Emmanuel Clave, Joelle Tobaly-Tapiero, Patricia Bittoun, Antoine Toubert, Hugues de Thé, Ali Saïb   +9 more
doaj   +1 more source

Cellular entry and uncoating of naked and quasi-enveloped human hepatoviruses

eLife, 2019
Many ‘non-enveloped’ viruses, including hepatitis A virus (HAV), are released non-lytically from infected cells as infectious, quasi-enveloped virions cloaked in host membranes.
Efraín E Rivera-Serrano, Olga González-López, Anshuman Das, Stanley M Lemon   +3 more
doaj   +1 more source

Insights Into the Antigenic Repertoire of Unclassified Synaptic Antibodies

Annals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 547-561, March 2026.
ABSTRACT Objective We sought to characterize the sixth most common finding in our neuroimmunological laboratory practice (tissue assay‐observed unclassified neural antibodies [UNAs]), combining protein microarray and phage immunoprecipitation sequencing (PhIP‐Seq). Methods Patient specimens (258; 133 serums; 125 CSF) meeting UNA criteria were profiled;
Michael Gilligan, John R. Mills, Paulina Vargas, Naveen K. Paramasivan, Connie E. Lesnick, Eati Basal, Surendra Dasari, James P. Fryer, Shannon R. Hinson, Joseph Laporta, Amy Espinal, Dennis Fitzgerald, Carolina Garcia, Anna E. Morenkova, Paola Pergami, Anna Shah, Andrew Knight, Reghann LaFrance Corey, Vanda A. Lennon, Anastasia Zekeridou, Sean J. Pittock, Divyanshu Dubey, Andrew McKeon   +22 more
wiley   +1 more source

Time-Resolved Imaging of Single HIV-1 Uncoating In Vitro and in Living Cells.

PLoS Pathogens, 2016
Disassembly of the cone-shaped HIV-1 capsid in target cells is a prerequisite for establishing a life-long infection. This step in HIV-1 entry, referred to as uncoating, is critical yet poorly understood.
Ashwanth C Francis, Mariana Marin, Jiong Shi, Christopher Aiken, Gregory B Melikyan   +4 more
doaj   +1 more source

Evolution of H5N1 Cross‐Species Transmission: Adaptive Mutations Driving Avian‐to‐Human Infection

Advanced Genetics, Volume 7, Issue 1, March 2026.
This review synthesizes current knowledge on the molecular mechanisms underpinning H5N1's host adaptation, focusing on key mutations in viral proteins. Critical mutations are discussed in detail, highlighting their roles in altering receptor specificity, promoting antiviral resistance, and expanding viral tropism. The review underscores the urgent need
Wenxin Man, Lin Du, Ying Liu, Zehan Pang, Hongyan Zhu, Bixia Hong, Zhichao Xu, Huahao Fan   +7 more
wiley   +1 more source

Low Temperature and Pressure Stability of Picornaviruses: Implications for Virus Uncoating [PDF]

Biophysical Journal, 1999
The family Picornaviridae includes several viruses of great economic and medical importance. Poliovirus replicates in the human digestive tract, causing disease that may range in severity from a mild infection to a fatal paralysis. The human rhinovirus is the most important etiologic agent of the common cold in adults and children.
Oliveira, Andréa C., Ishimaru, Daniella, Gonçalves, Rafael B., Smith, Thomas J., Mason, Peter, Sá-Carvalho, Daniel, Silva, Jerson L.   +6 more
openaire   +2 more sources

Activation of PI3K, Akt, and ERK during early rotavirus infection leads to V-ATPase-dependent endosomal acidification required for uncoating. [PDF]

PLoS Pathogens, 2018
The cellular PI3K/Akt and/or MEK/ERK signaling pathways mediate the entry process or endosomal acidification during infection of many viruses. However, their roles in the early infection events of group A rotaviruses (RVAs) have remained elusive.
Mahmoud Soliman, Ja-Young Seo, Deok-Song Kim, Ji-Yun Kim, Jun-Gyu Park, Mia Madel Alfajaro, Yeong-Bin Baek, Eun-Hyo Cho, Joseph Kwon, Jong-Soon Choi, Mun-Il Kang, Sang-Ik Park, Kyoung-Oh Cho   +12 more
doaj   +1 more source