Results 91 to 100 of about 204,789 (305)

A new genus-level geminivirus lineage isolated from the South African fynbos [PDF]

open access: yes, 2011
A new genus-level geminivirus lineage isolated from the South African fynbos. The state of the art on the diversity of plant viruses mainly concerns those causing symptoms affecting plants of economic interest.
Bernardo, Pauline
core  

Genome editing technologies to fight infectious diseases [PDF]

open access: yes, 2017
Genome editing by programmable nucleases represents a promising tool that could be exploited to develop new therapeutic strategies to fight infectious diseases.
Barzon, Luisa   +2 more
core   +1 more source

Tobacco mosaic virus virulence and avirulence

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1999
In celebration of a century of research on tobacco mosaic virus that initiated the science of virology, I review recent progress relative to earlier contributions concerning how viruses cause diseases of plants and how plants defend themselves from viruses.
openaire   +3 more sources

AIEgen‐Based Proactive Early Warning System and Precise Treatment Strategy for Monkeypox Prevention and Control

open access: yesAdvanced Science, EarlyView.
An intelligent early warning and treatment system for monkeypox, utilizing a sprayable AIEgen‐ liquid dressing (AIE@LD) that responds to lesion pH. Integrated with a smartphone app and cloud platform, it enables real‐time infection detection via fluorescence imaging and triggers on‐demand photodynamic therapy under white light, effectively eradicating ...
Wei Wang   +14 more
wiley   +1 more source

Replication efficiency of oncolytic vaccinia virus in cell cultures prognosticates the virulence and antitumor efficacy in mice

open access: yesJournal of Translational Medicine, 2011
Background We have shown that insertion of the three vaccinia virus (VACV) promoter-driven foreign gene expression cassettes encoding Renilla luciferase-Aequorea GFP fusion protein, β-galactosidase, and β-glucuronidase into the F14.5L, J2R, and A56R loci
Yu Yong A   +3 more
doaj   +1 more source

A Comparison of the Vertical Transmission of High- and Low-Virulence Nucleopolyhedrovirus Strains in Lymantria Dispar L.

open access: yesInsects, 2020
Baculoviruses can persist in insect host organisms after infection and may be vertically transmitted to the next generation, in which they may be reactivated.
Yuriy B. Akhanaev   +4 more
doaj   +1 more source

Bluetongue virus without NS3/NS3a expression is not virulent and protects against virulent bluetongue virus challenge

open access: yesJournal of General Virology, 2014
Bluetongue is a disease in ruminants caused by the bluetongue virus (BTV), and is spread by Culicoides biting midges. Bluetongue outbreaks cause huge economic losses and death in sheep in several parts of the world. The most effective measure to control BTV is vaccination.
Feenstra, F.   +4 more
openaire   +2 more sources

Deletion of the vaccinia virus growth factor gene reduces virus virulence [PDF]

open access: yesJournal of Virology, 1988
The vaccinia virus growth factor (VGF) gene encodes a polypeptide with amino acid sequence homology to epidermal growth factor (EGF) and transforming growth factor alpha and is present twice, once at each end of the virus genome within the inverted terminal repetition.
R M, Buller   +4 more
openaire   +2 more sources

Genome‐Wide Codon Reprogramming Enables a Multifactorially Attenuated Influenza Vaccine with Broad Cross‐Protection

open access: yesAdvanced Science, EarlyView.
Genome‐wide codon reprogramming of influenza A virus introduces 1956 synonymous mutations across five segments and elevates CpG content, causing defective NA packaging, loss of NS1 accumulation, and enhanced ZAP‐mediated antiviral responses without affecting RNA or protein synthesis. These mechanisms result in profound attenuation and potent homologous
Yang Wang   +13 more
wiley   +1 more source

Pathogénicité du virus atténué de la peste des petits ruminants chez des moutons et des chèvres

open access: yesRevue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1990
Avec les passages du virus PPR sur les cellules Vero, on a noté une diminution progressive de sa virulence vis-à-vis des chevreaux. Les chèvres inoculées avec le virus au 60e passage ont présenté la maladie clinique avec des cas de mortalité alors que ...
F.D. Adu   +3 more
doaj   +1 more source

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