Results 101 to 110 of about 111,893 (295)

Bluetongue virus without NS3/NS3a expression is not virulent and protects against virulent bluetongue virus challenge

open access: yesJournal of General Virology, 2014
Bluetongue is a disease in ruminants caused by the bluetongue virus (BTV), and is spread by Culicoides biting midges. Bluetongue outbreaks cause huge economic losses and death in sheep in several parts of the world. The most effective measure to control BTV is vaccination.
Feenstra, F.   +4 more
openaire   +2 more sources

Shotgun Metagenomic Profiling of the Gut Virome in Prodromal and Confirmed Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
We conducted a nested case‐control study within the Nurses’ Health Study and the Health Professionals Follow‐up Study to examine the role of the gut virome (GV) in Parkinson's disease (PD). We applied a novel metagenomic virome profiling approach, Bioinformatic Application for Quantification and Labeling of Viral taxonomy (BAQLaVa), to prospectively ...
Deepika Dinesh   +7 more
wiley   +1 more source

Effect of ORFV113 on virus virulence and pathogenesis in sheep.

open access: yes, 2021
(A) Sheep were scarified in the right labial commissure, inoculated with virus OV-IA82RV113HA (RV113; sheep # 15, 40, 93, and 430) or OV-IA82Δ113 (Δ113; sheep # 5, 11, 55 and 130), or treated with PBS (control; sheep # 25, 38 and 81), and monitored for ...
Gustavo Delhon (4336627)   +3 more
core   +1 more source

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

open access: yesAnimal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary   +7 more
wiley   +1 more source

Virulence of Japanese Encephalitis Virus Genotypes I and III, Taiwan

open access: yesEmerging Infectious Diseases, 2017
The virulence of genotype I (GI) Japanese encephalitis virus (JEV) is under debate. We investigated differences in the virulence of GI and GIII JEV by calculating asymptomatic ratios based on serologic studies during GI- and GIII-JEV endemic periods. The
Yi-Chin Fan   +13 more
doaj   +1 more source

Tobacco mosaic virus virulence and avirulence

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1999
In celebration of a century of research on tobacco mosaic virus that initiated the science of virology, I review recent progress relative to earlier contributions concerning how viruses cause diseases of plants and how plants defend themselves from viruses.
openaire   +3 more sources

MOLECULAR MECHANISM OF CHIKUNGUNYA VIRUS VIRULENCE

open access: yes, 2021
Ph.DDOCTOR OF PHILOSOPHY ...
CHEN HUIXIN
core  

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

open access: yesAnimal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang   +10 more
wiley   +1 more source

Role of nonstructural protein NS2A in flavivirus assembly

open access: yes, 2008
Flavivirus nonstructural (NS) proteins are involved in RNA replication and modulation of the host antiviral response; however, evidence is mounting that some NS proteins also have essential roles in virus assembly.
Pijlman, G.P.   +5 more
core   +1 more source

Recent Advances in Virus–Host Interactions, Antiviral Bioactive Compounds, and Breeding for Disease Resistance of Porcine Epidemic Diarrhea Virus

open access: yesAnimal Research and One Health, EarlyView.
Basic research on the PEDV infection cycle and virus–host interactions advances the development of anti‐PEDV drugs and disease‐resistant breeding and helps strengthen disease prevention and control while reducing economic losses in the swine industry.
Heyong Wu   +8 more
wiley   +1 more source

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