Results 91 to 100 of about 2,212,038 (235)

Partly 5` Untranslated Region (5` UTR)-Based Phylogenetic Analysis of Three Hepatitis C Virus Isolates From Jakarta, Indonesia: a Preliminary Study [PDF]

open access: yes, 2014
Currently, we reported results of a nested PCR assay specific 5` UTR region of HCV genome that showed three different patterns of DNA fragments (single expected specific DNA band, single DNA band higher in size than an expected band, and multiple DNA ...
Rosilawati, M. L. (Maria)   +1 more
core   +2 more sources

Virulence in murine model shows the existence of two distinct populations of Brazilian Vaccinia virus strains. [PDF]

open access: yesPLoS ONE, 2008
Brazilian Vaccinia virus had been isolated from sentinel mice, rodents and recently from humans, cows and calves during outbreaks on dairy farms in several rural areas in Brazil, leading to high economic and social impact.
Jaqueline Maria Siqueira Ferreira   +13 more
doaj   +1 more source

Impact of RNA Virus Evolution on Quasispecies Formation and Virulence

open access: yesInternational Journal of Molecular Sciences, 2019
RNA viruses are known to replicate by low fidelity polymerases and have high mutation rates whereby the resulting virus population tends to exist as a distribution of mutants.
Madiiha Bibi Mandary   +2 more
semanticscholar   +1 more source

Dengue Virus Markers of Virulence and Pathogenicity [PDF]

open access: yesFuture Virology, 2009
The increased spread of dengue fever and its more severe form, dengue hemorrhagic fever, have made the study of the mosquito-borne dengue viruses that cause these diseases a public health priority. Little is known about how or why the four different (serotypes 1-4) dengue viruses cause pathology in humans only, and there have been no animal models of ...
openaire   +2 more sources

MiRNA Targeted NP Genome of Live Attenuated Influenza Vaccines Provide Cross-Protection against a Lethal Influenza Virus Infection

open access: yesVaccines, 2020
The miRNA-based strategy has been used to develop live attenuated influenza vaccines. In this study, the nucleoprotein (NP) genome segment of the influenza virus was inserted by different perfect miRNA-192-5p target sites, and the virus was rescued by ...
Feixia Gao   +8 more
doaj   +1 more source

Genomic polymorphism of the pandemic A (H1N1) influenza viruses correlates with viral replication, virulence, and pathogenicity in vitro and in vivo. [PDF]

open access: yesPLoS ONE, 2011
The novel pandemic A (H1N1) virus was first identified in Mexico in April 2009 and quickly spread worldwide. Like all influenzas, the H1N1 strain-specific properties of replication, virulence, and pathogenicity are a result of the particular genomic ...
Lili Xu   +13 more
doaj   +1 more source

Poliovirus intrahost evolution is required to overcome tissue-specific innate immune responses. [PDF]

open access: yes, 2017
RNA viruses, such as poliovirus, have a great evolutionary capacity, allowing them to quickly adapt and overcome challenges encountered during infection.
Andino, Raul   +6 more
core   +3 more sources

In vivo evolution of viral virulence: switching of deformed wing virus between hosts results in virulence changes and sequence shifts

open access: yesEnvironmental Microbiology, 2018
The health of the Western honey bee is threatened by a global epidemic of deformed wing virus (DWV) infections driven by the ectoparasitic mite Varroa destructor acting as mechanical and biological virus vector. Three different variants of DWV, DWV-A, -B
S. Gisder   +3 more
semanticscholar   +1 more source

Tobacco mosaic virus virulence and avirulence

open access: yesPhilosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1999
In celebration of a century of research on tobacco mosaic virus that initiated the science of virology, I review recent progress relative to earlier contributions concerning how viruses cause diseases of plants and how plants defend themselves from viruses.
openaire   +3 more sources

In Ovo Models to Predict Virulence of Highly Pathogenic Avian Influenza H5-Viruses for Chickens and Ducks

open access: yesViruses
Highly pathogenic avian influenza (HPAI) H5-viruses are circulating in wild birds and are repeatedly introduced to poultry causing outbreaks in the Netherlands since 2014.
Luca Bordes   +7 more
doaj   +1 more source

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