Results 91 to 100 of about 111,893 (295)
Serp2, an inhibitor of the interleukin-1beta-converting enzyme, is critical in the pathobiology of myxoma virus [PDF]
, 1998 Recently, myxoma virus was shown to encode an additional member of the serpin superfamily. The viral gene, called serp2, was cloned, and the Serp2 protein was shown to specifically bind to interleukin-1beta (IL-1beta)-converting enzyme (ICE), thus ...
Messud-Petit, Frédérique +6 more
core
Poxvirus A51R: A microtubule maestro and virulence virtuoso [PDF]
Seo et al.1 shed light on virus-host interactions as they reveal how poxvirus A51R stabilizes microtubules in infected cells, which impacts vaccinia virus virulence in mice by potentially inhibiting reactive-oxygen-species-dependent antiviral responses ...
G.W. Gant Luxton +3 more
core +1 more source
Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression
Advanced Science, EarlyView.The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren +20 more
wiley +1 more source
From Defense Executor to Engineering Target: Harnessing Lignin for Crop Resistance
Advanced Science, EarlyView.Lignin serves as both a physical and chemical executor of broad‐spectrum plant immunity. This review systematically summarizes classical and recent advances in lignin‐mediated immunity, outlines the multifaceted regulatory modules controlling lignification under biotic stress, discusses key physiological and biochemical mechanisms behind lignin‐based ...
Yanwen Yu +6 more
wiley +1 more source
Theme and variations in the evolutionary pathways to virulence of an RNA plant virus species.
PLoS Pathogens, 2007 The diversity of a highly variable RNA plant virus was considered to determine the range of virulence substitutions, the evolutionary pathways to virulence, and whether intraspecific diversity modulates virulence pathways and propensity.
Agnès Pinel-Galzi +13 more
doaj +1 more source
Molecular determinants of bluetongue virus virulence [PDF]
, 2015 Bluetongue virus (BTV) is an arbovirus and the cause of “bluetongue”, a major infectious disease of ruminants. Whilst the BTV structure and replication strategies are well elucidated, less is known on the genetic variability of BTV and the molecular ...
Janowicz, Anna Agata
core
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel +13 more
wiley +1 more source
, 2010 The purpose of this study was to evaluate the level of tungro virus virulence from some endemic areas, the suitability of planting resistant varieties, and resistance of rice germplasms.
Suprihanto, I Nyoman Widiarta, Dede Kusdiaman\u27
core +2 more sources
The impact of NA mutations on virus virulence in mice.
, 2023 Mice (n = 8 per group) were inoculated intranasally with 105 PFU of the indicated viruses or 50 μL PBS (sham group). Average bodyweight (A) and the survival curve (B) were determined.
Donata Hoffmann (3154338) +24 more
core +1 more source
Advances and perspectives in animal models of human hepatitis A virus
Animal Models and Experimental Medicine, EarlyView.Following HAV infection, humans, non‐human primates, and Ifnar1−/− mice develop characteristic manifestations of hepatitis A, including fecal viral shedding, elevated serum ALT levels, and inflammatory cell infiltration in the liver. In contrast, HAV‐infected human liver chimeric mice exhibit fecal viral shedding but do not develop clinical features of
Jian Li +3 more
wiley +1 more source