Results 101 to 110 of about 205,339 (347)

Deletion of the vaccinia virus growth factor gene reduces virus virulence [PDF]

Journal of Virology, 1988
The vaccinia virus growth factor (VGF) gene encodes a polypeptide with amino acid sequence homology to epidermal growth factor (EGF) and transforming growth factor alpha and is present twice, once at each end of the virus genome within the inverted terminal repetition.
R M, Buller, S, Chakrabarti, J A, Cooper, D R, Twardzik, B, Moss   +4 more
openaire   +2 more sources

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel, Phillip A. Engen, Glen D. Souza, Sarah Khalife, Donyea Moore, Lauren Kret, Pedro Escobedo, Stefan J. Green, Ankur Naqib, Peter Filip, Peter Papagiannopoulos, Bobby A. Tajudeen, Mahboobeh Mahdavinia, Pete S. Batra   +13 more
wiley   +1 more source

Replication efficiency of oncolytic vaccinia virus in cell cultures prognosticates the virulence and antitumor efficacy in mice

Journal of Translational Medicine, 2011
Background We have shown that insertion of the three vaccinia virus (VACV) promoter-driven foreign gene expression cassettes encoding Renilla luciferase-Aequorea GFP fusion protein, β-galactosidase, and β-glucuronidase into the F14.5L, J2R, and A56R loci
Yu Yong A, Chen Nanhai G, Zhang Qian, Szalay Aladar A   +3 more
doaj   +1 more source

A Comparison of the Vertical Transmission of High- and Low-Virulence Nucleopolyhedrovirus Strains in Lymantria Dispar L.

Insects, 2020
Baculoviruses can persist in insect host organisms after infection and may be vertically transmitted to the next generation, in which they may be reactivated.
Yuriy B. Akhanaev, Irina A. Belousova, Darya A. Lebedeva, Sergey V. Pavlushin, Vyacheslav V. Martemyanov   +4 more
doaj   +1 more source

Sheeppox Virus Kelch-Like Gene SPPV-019 Affects Virus Virulence [PDF]

Journal of Virology, 2007
ABSTRACT Sheeppox virus (SPPV), a member of the Capripoxvirus genus of the Poxviridae , is the etiologic agent of a significant disease of sheep in the developing world. Genomic analysis of pathogenic and vaccine capripoxviruses identified genes with potential roles in virulence and
Balinsky, C. A., Delhon, Gustavo A., Afonso, C. L., Risatti, G. R., Borca, M. V., French, R. A., Tulman, E. R., Geary, S. J., Rock, D. L.   +8 more
openaire   +2 more sources

Chicken Pulmonary MicroRNAs Targeting the PB2 (Segment 1) of Avian Influenza Virus

Animal Research and One Health, EarlyView.
The PB2 segment of H5N1 is essential for replication and host adaptation. We screened 200 miRNAs and identified five (gga‐miR‐17‐3p, gga‐miR‐29a‐5p, gga‐miR‐1718, gga‐miR‐16c‐5p, and gga‐miR‐1744‐5p) using thermodynamic stability of heteroduplex, seed sequence complementarity, conservation, and accessibility, offering insights into host antiviral ...
Akanksha Choudhary, Nidhishree N. S, Rakesh Kumar Pundir, Muhasin Asaf V. N, Anamika Mishra, Ashwin Ashok Raut, Megha Agarwal, Amod Kumar   +7 more
wiley   +1 more source

Pathogénicité du virus atténué de la peste des petits ruminants chez des moutons et des chèvres

Revue d’Elevage et de Médecine Vétérinaire des Pays Tropicaux, 1990
Avec les passages du virus PPR sur les cellules Vero, on a noté une diminution progressive de sa virulence vis-à-vis des chevreaux. Les chèvres inoculées avec le virus au 60e passage ont présenté la maladie clinique avec des cas de mortalité alors que ...
F.D. Adu, T. Joannis, E. Nwosuh, A. Abegunde   +3 more
doaj   +1 more source

Altered expression of cytokines in mice infected intranasally with two syncytial variants of Herpes simplex virus type 1 [PDF]

, 2014
Immune evasion strategies are important for the onset and the maintenance of viral infections. Many viruses have evolved mechanisms to counteract or suppress the host immune response.
Adler, Ankel, Artuso, Canalejo Castrillero, Carlos A. Pujol, Carlucci, Chew, Chiang, Ellermann-Eriksen, Finton, Florencia N. Linero, Glorieux, Hull, Karasneh, Lucey, Luis A. Scolaro, M. Carolina Artuso, M. Josefina Carlucci, Martinez, Mateu, Mogensen, Murphy, Nandakumar, Opal, Paludan, Reading, Romagnani, Rosa Wainstok, Silvina Gazzaniga, Smyth, Stumpf, Teng   +31 more
core   +2 more sources

The Role of miRNAs in Chicken Immune Regulation and Prospects for Disease‐Resistant Breeding

Animal Research and One Health, EarlyView.
A schematic workflow illustrating the screening of disease‐resistant miRNAs and the generation of miRNA‐based disease‐resistant chickens via PGC‐mediated germline genome editing. ABSTRACT MicroRNAs (miRNAs) are emerging as pivotal regulators of the immune system, playing a decisive role in shaping disease resistance in chicken.
Qiangzhou Wang, Weiran Wu, Qingqing Cai, Jiaxing Wang, Qi Gao, Muhammad Iftikhar, Yulin Bi, Hao Bai, Lihong Gu, Guobin Chang, Shihao Chen   +10 more
wiley   +1 more source

Virus and host factors affecting the clinical outcome of bluetongue virus infection [PDF]

, 2014
Bluetongue is a major infectious disease of ruminants caused by bluetongue virus (BTV), an arbovirus transmitted by Culicoides. Here, we assessed virus and host factors influencing the clinical outcome of BTV infection using a single experimental ...
Caporale, Marco, Di Gialleonorado, Luigina, Di Ventura, Mauro, Janowicz, Anna, Mertens, Peter, Palmarini, Massimo, Savini, Giovanni, Shaw, Andrew, Van Rijn, Piet A., Wilkie, Gavin   +9 more
core   +3 more sources