Results 131 to 140 of about 1,547,632 (301)

A unique substitution at position 333 on the glycoprotein of rabies virus street strains isolated from non-hematophagous bats in Brazil

, 2009
The amino acid R or K at position 333 on the glycoprotein of the rabies virus is considered necessary for virulence in adult mice. Although some exceptions exist, substitution at this position causes expression of a phenotype that is either less ...
SAKAI, T., G. Sato, CUNHA, E. M. S., T. Sakai, T. Itou, HIRANO, S., Y. Kobayashi, MOTIZUKI, N., F. H. Ito, E. M. S. Cunha, ITOU, T., KOBAYASHI, Y., S. Hirano, ITO, F. H., SATO, G., N. Motizuki   +15 more
core   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Correction for Riemersma et al., "Rapid Evolution of Enhanced Zika Virus Virulence during Direct Vertebrate Transmission Chains". [PDF]

J Virol, 2022
Riemersma KK, Jaeger AS, Crooks CM, Braun KM, Weger-Lucarelli J, Ebel GD, Friedrich TC, Aliota MT.   +7 more
europepmc   +1 more source

Japanese encephalitis virus antigenic variants with characteristic differences in neutralization resistance and mouse virulence

, 1997
[[abstract]]Two different plaque variants of Japanese encephalitis virus were selected from a wild-type Taiwanese isolate using Vero cells. One variant was found to exhibit small plaque morphology with retarded virus replication kinetics in Vero cells ...
Wu, SC;Lian, WC;Hsu, LC;Liau, MY, null Ming-Yi Liau, null Wei-Cheng Lian, null Suh-Chin Wu, null Li-Ching Hsu   +4 more
core   +1 more source

The central metabolism regulator EIIAGlc switches Salmonella from growth arrest to acute virulence through activation of virulence factor secretion [PDF]

, 2014
The ability of Salmonella to cause disease depends on metabolic activities and virulence factors. Here, we show that a key metabolic protein, EIIAGlc, is absolutely essential for acute infection, but not for Salmonella survival, in a mouse typhoid fever ...
Timo Glatter, Dirk Bumann,, Glatter, T. ; https://orcid.org/, Timo Glatter,, Dirk Bumann, Alain Mazé, Maze, A., Alain Mazé,, Bumann, D., Glatter T, Mazé A, Bumann D   +11 more
core   +1 more source

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

Virulence evolution of a salmonid virus following a host jump.

PLoS Pathogens
Emergent viral diseases remain a critical obstacle to welfare across landscapes and species, encompassing humans, wildlife, and agriculture. Following a jump to a novel host, the severity of disease resulting from infection is a critical determinant of ...
Malina M Loeher, Gael Kurath, David A Kennedy, Joanne E Salzer, William N Batts, Rachel B Breyta, Andrew R Wargo   +6 more
doaj   +1 more source

C Protein is Essential for Canine Distemper Virus Virulence and Pathogenicity in Ferrets. [PDF]

J Virol, 2021
Siering O, Sawatsky B, Pfaller CK.
europepmc   +1 more source

Protein Glutamylation: From Cytoskeleton to Signaling

Med Research, EarlyView.
Tubulin glutamylation, γ‐glutamylation, and nontubulin glutamylation are distinct yet interconnected post‐translational modifications that regulate diverse physiological and pathological processes, including cytoskeletal organization, cell cycle progression, immunity, metabolism, and disease development.
Jiayuan Chen, Yi Yuan, Qingquan Yu, Xinyue Wang, Hui Wang   +4 more
wiley   +1 more source

Associations between virus single infection or coinfection and respiratory symptoms in young children: A community-based cohort study

International Journal of Infectious Diseases
Objectives: Virus coinfections are common in young children. We quantified single and coinfections and their association with acute respiratory illness (ARI) in a prospective community-based cohort. Methods: Healthy children (aged
Emma Hauser-van Westrhenen, Laia Junquera Guinovart, Rob Schuurman, Michiel van Boven, Marc Bonten, Patricia Bruijning-Verhagen   +5 more
doaj   +1 more source