Results 131 to 140 of about 111,893 (295)

Rapid evolution of enhanced Zika virus virulence during direct vertebrate transmission chains. [PDF]

J Virol, 2021
Riemersma KK, Jaeger AS, Crooks CM, Braun KM, Weger-Lucarelli J, Ebel GD, Friedrich TC, Aliota MT.   +7 more
europepmc   +1 more source

Coronavirus gene 7 counteracts host defenses and modulates virus virulence

, 2011
Transmissible gastroenteritis virus (TGEV) genome contains three accessory genes: 3a, 3b and 7. Gene 7 is only present in members of coronavirus genus a1, and encodes a hydrophobic protein of 78 aa.
Becares Martina, Becares, Martina, Plana Joan, Cruz, Jazmina L. G., Sonia Zuñiga, Sola, Isabel, Alberca Berta, Luis Enjuanes, Zuñiga Sonia, Enjuanes Sánchez, Luis, Zuñiga, Sonia, Enjuanes, Luis, Berta Alberca, Isabel Sola, Martina Becares, Solá Gurpegui, Isabel, Jazmina L. G. Cruz, Plana, Joan, Zúñiga Lucas, Sonia, Alberca, Berta, Sola Isabel, Cruz Jazmina L. G., Joan Plana, Enjuanes Luis, Jazmina L G Cruz   +24 more
core   +1 more source

Nanopore direct RNA sequencing and the epitranscriptome: Advances in mapping native RNA landscapes

iMeta, EarlyView.
Nanopore direct RNA sequencing advances transcriptomics by capturing full‐length transcripts and multiple RNA modifications; this review details its principles, workflows, tools, applications, challenges, and future research potential. Abstract Nanopore direct RNA sequencing (DRS) has transformed transcriptomics by enabling single‐molecule, long‐read ...
Tianyuan Zhang, Jia Li, Chao Tang, You Wu, Hao Wu, Xi‐Tong Zhu, Ziyang Luo, Hang Qin, Lishan Ding, Yu Zeng, Shiou Yih Lee, Xiaotao Shen, Shiwen Gao, Zhaoyang Tian, Qian Tang, Mian Li, Muhammad Tahir Ul Qamar, Yang Dong, Komivi Dossa, Yaxuan Zhang, Hu Chen, Sanqi An, Xiang Yu, Lu Chen, Dingjie Wang, Shengli Li, Ling‐Ling Chen, Yanqiang Li   +27 more
wiley   +1 more source

Associations between virus single infection or coinfection and respiratory symptoms in young children: A community-based cohort study

International Journal of Infectious Diseases
Objectives: Virus coinfections are common in young children. We quantified single and coinfections and their association with acute respiratory illness (ARI) in a prospective community-based cohort. Methods: Healthy children (aged
Emma Hauser-van Westrhenen, Laia Junquera Guinovart, Rob Schuurman, Michiel van Boven, Marc Bonten, Patricia Bruijning-Verhagen   +5 more
doaj   +1 more source

Increasing the frequency of omicron variant mutations boosts the immune response and may reduce the virus virulence. [PDF]

Microb Pathog, 2022
Dawood AA.
europepmc   +1 more source

Tiny carriers, big impact: How Fusobacterium nucleatum extracellular vesicles drive oral diseases and beyond

Interdisciplinary Medicine, EarlyView.
This review explores how Fusobacterium nucleatum extracellular vesicles drive local oral diseases and distal pathologies via sophisticated cross‐compartment cross talk. It highlights the transformative potential of these “tiny carriers” as next‐generation molecular intermediaries for advanced health monitoring and innovative bio‐interventions by ...
Rongyang Ma, Jiahui Huang, Yitong Chen, Haoxuan Wang, Hang Zou, Wanghong Zhao, Zilong Deng   +6 more
wiley   +1 more source

Multi‐omics biomarkers for intestinal infection and inflammation in inflammatory bowel disease: Current evidence, translational challenges, and diagnostic opportunities

Interdisciplinary Medicine, EarlyView.
Prospective multi‐site cohorts, multi‐omics profiling, and computational analysis may help identify biomarker patterns across clinical settings in IBD and superimposed infections. With further mechanistic and clinical validation, these signals could support the development of practical multi‐analyte tools for more precise diagnosis and management ...
Ziyu Yang, Jiayi Yao, Xinxian Zhao, Yan Xu, Yifan Chen, Tianchi Chen, Ying Jian, Min Li   +7 more
wiley   +1 more source

Amelioration of Beta Interferon Inhibition by NS4B Contributes to Attenuating Tembusu Virus Virulence in Ducks. [PDF]

Front Immunol, 2021
Zhang W, Zeng M, Jiang B, Lu T, Guo J, Hu T, Wang M, Jia R, Zhu D, Liu M, Zhao X, Yang Q, Wu Y, Zhang S, Ou X, Liu Y, Zhang L, Yu Y, Pan L, Cheng A, Chen S.   +20 more
europepmc   +1 more source

Is modulating virus virulence by induced systemic resistance realistic?

, 2015
Induction of plant resistance, either achieved by chemicals (systemic acquired resistance, SAR) or by rhizobacteria (induced systemic resistance, ISR) is a possible and/or complementary alternative to manage virus infections in crops.
F. Gozzo, F. Faoro
core   +1 more source

Targeting the intratumoral microbiota to overcome cancer immunotherapy resistance

Interdisciplinary Medicine, EarlyView.
This review delineates the mechanisms of intratumoral microbiota in cancer immunotherapy resistance, and offers strategies for microbiota‐targeted precision immunotherapy. Abstract Cancer remains a significant global health threat. The tumor microenvironment (TME) is a sophisticated ecological niche that exerts a pivotal effect on treatment outcomes ...
Bufu Tang, Tong Jiang, Yaling Lin, Wei Zhang, Hongjie Fan, Minjie Yang, Bingzhe Li, Yaozu Liu, Changyu Li, Xuran Jin, Wen Zhang, Zhiping Yan, Qianqian Zhao, Xuefeng Kan, Xudong Qu   +14 more
wiley   +1 more source