Results 51 to 60 of about 205,339 (347)

Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]

, 2011
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle, Lieselotte eVande Walle, Mohamed eLamkanfi, Mohamed eLamkanfi   +3 more
core   +2 more sources

Rift Valley fever virus 78kDa envelope protein attenuates virus replication in macrophage-derived cell lines and viral virulence in mice.

PLoS Neglected Tropical Diseases, 2021
Rift Valley fever virus (RVFV) is a mosquito-borne bunyavirus with a wide host range including ruminants and humans. RVFV outbreaks have had devastating effects on public health and the livestock industry in African countries.
Kaori Terasaki, Birte Kalveram, Kendra N Johnson, Terry Juelich, Jennifer K Smith, Lihong Zhang, Alexander N Freiberg, Shinji Makino   +7 more
doaj   +1 more source

Virulence of H5N1 virus in mice attenuates after in vitro serial passages

Virology Journal, 2011
The virulence of A/Vietnam/1194/2004 (VN1194) in mice attenuated after serial passages in MDCK cells and chicken embryos, because the enriched large-plaque variants of the virus had significantly reduced virulence.
Li Yongqiang, Xia Yukun, Zhan Dawei, Hu Yi, Chang Guohui, Liu Bohua, Li Jing, Yang Yinhui, Zhu Qingyu   +8 more
doaj   +1 more source

Helicobacter pylori and Epstein-Barr virus infection in gastric diseases: Correlation with IL-10 and IL1RN polymorphism. [PDF]

, 2019
Introduction: Helicobacter pylori and Epstein-Barr virus (EBV) infection have recently 23 been shown to be associated with gastric diseases. Polymorphisms in genes encoding 24 cytokines such as interleukin 10 (IL-10) and interleukin 1 Receptor (IL-1RN ...
Anna Giammanco, Cannella, Sara, Cesare Gagliardi, Chiara Mascarella, Dario Lipari, Giuseppina Capra, Letizia Scola, Nicola Serra, Paola Di Carlo, SCIORTINO, MIRIAM, SIMONTE, MARIA ROSA, Teresa Fasciana   +11 more
core   +1 more source

Vertical transmission selects for reduced virulence in a plant virus and for increased resistance in the host.

PLoS Pathogens, 2014
For the last three decades, evolutionary biologists have sought to understand which factors modulate the evolution of parasite virulence. Although theory has identified several of these modulators, their effect has seldom been analysed experimentally. We
Israel Pagán, Nuria Montes, Michael G Milgroom, Fernando García-Arenal   +3 more
doaj   +1 more source

Comparison of Aerosol Stability of Different Variants of Ebola Virus and Marburg Virus and Virulence of Aerosolised Ebola Virus in an Immune-Deficient Mouse

Viruses, 2022
During outbreaks of virus diseases, many variants may appear, some of which may be of concern. Stability in an aerosol of several Ebola virus and Marburg virus variants was investigated.
Sophie J. Smither, Lin S. Eastaugh, Mark S. Lever   +2 more
doaj   +1 more source

One-way trip: Influenza virus' adaptation to gallinaceous poultry may limit its pandemic potential [PDF]

, 2014
We hypothesise that some influenza virus adaptations to poultry may explain why the barrier for human-to-human transmission is not easily overcome once the virus has crossed from wild birds to chickens.
Alexander, Baigent, Banks, Banks, Belser, Blumenkrantz, Bosch, Brass, Bullough, Butt, Castrucci, Cauldwell, Chan, Chen, Chen, Cheng, Chutinimitkul, Cohen, Connor, Costa, Cotter, Cowling, Cox, De Jong, Dorigatti, DuBois, Elderfield, England, Everitt, Gabbard, Galloway, Gambaryan, Gambaryan, Gao, Garten, Handel, Harvey, Hatta, Hay, Herfst, Hoffmann, Imai, Jia, Karron, Keleta, Killingley, Koerner, Koopmans, Krenn, Kuchipudi, Li, Li, Lin, Lin, Linster, Luke, Maines, Matrosovich, Matrosovich, Matrosovich, Matrosovich, Matsuoka, Munier, Neumann, O'Donnell, Pappas, Peiris, Perdue, Reed, Roberts, Robinson, Roche, Rogers, Rott, Russell, Russell, Schrauwen, Shelton, Shi, Skehel, Smeenk, Sorrell, Sorrell, Steinhauer, Stevens, Suguitan, Sun, Tellier, Tharakaraman, Thoennes, Tumpey, Vines, Wan, Wang, Washington, Webster, Wei, Xiong, Yen, Zhang, Zhou, Zhou   +101 more
core   +2 more sources

Dengue Virus Evolution and Virulence Models [PDF]

Clinical Infectious Diseases, 2007
Dengue virus transmission has increased dramatically in the past 2 decades, making this virus one of the most important mosquito-borne human pathogens. The emergence of dengue hemorrhagic fever in most tropical countries has made its control a public health priority, but no vaccines or treatments exist.
openaire   +2 more sources

Increasing clinical virulence in two decades of the Italian HIV epidemic. [PDF]

PLoS Pathogens, 2009
The recent origin and great evolutionary potential of HIV imply that the virulence of the virus might still be changing, which could greatly affect the future of the pandemic.
Viktor Müller, Franco Maggiolo, Fredy Suter, Nicoletta Ladisa, Andrea De Luca, Andrea Antinori, Laura Sighinolfi, Eugenia Quiros-Roldan, Giampiero Carosi, Carlo Torti   +9 more
doaj   +1 more source

Virulence and transmission characteristic of H3N8 avian influenza virus circulating in chickens in China. [PDF]

Virulence
Mei M, Zhang X, Wu Q, Xu M, Zhao Y.
europepmc   +2 more sources