Results 41 to 50 of about 111,893 (295)

Increasing clinical virulence in two decades of the Italian HIV epidemic. [PDF]

PLoS Pathogens, 2009
The recent origin and great evolutionary potential of HIV imply that the virulence of the virus might still be changing, which could greatly affect the future of the pandemic.
Viktor Müller, Franco Maggiolo, Fredy Suter, Nicoletta Ladisa, Andrea De Luca, Andrea Antinori, Laura Sighinolfi, Eugenia Quiros-Roldan, Giampiero Carosi, Carlo Torti   +9 more
doaj   +1 more source

A new inhibitor of apoptosis from vaccinia virus and eukaryotes.

, 2007
A new apoptosis inhibitor is described from vaccinia virus, camelpox virus, and eukaryotic cells. The inhibitor is a hydrophobic, multiple transmembrane protein that is resident in the Golgi and is named GAAP (Golgi anti-apoptotic protein).
Hollinshead, M, Smith, GL, van Kuppeveld, FJM, van Kuppeveld Frank J. M, Lu, X., Smith, G.L., Xin Lu, Gubser, C, Smith Geoffrey L, Bergamaschi, D., Bergamaschi Daniele, Hollinshead Michael, Caroline Gubser, Hollinshead, M., van Kuppeveld, FJ, Bergamaschi, D, Kuppeveld, F.J.M. van, Gubser Caroline, Geoffrey L Smith, Gubser, C., Frank J M van Kuppeveld, Michael Hollinshead, Lu Xin, Daniele Bergamaschi, Lu, Xin, Lu, X   +25 more
core   +2 more sources

Molecular anatomy of mouse hepatitis virus persistence: coevolution of increased host cell resistance and virus virulence.

, 1996
Persistent infection of murine astrocytoma (DBT) cells with mouse hepatitis virus (MHV) has been established. From this in vitro virus-host system, persistence is mediated at the level of cellular MHV receptor (MHVR) expression and increased virus ...
Baric, Ralph S., Chen, Wan
core   +2 more sources

Synergistic effect of PB2 283M and 526R contributes to enhanced virulence of H5N8 influenza viruses in mice

Veterinary Research, 2017
Highly pathogenic avian influenza (HPAI) H5N8 virus has caused considerable economic losses to poultry industry and poses a great threat to public health.
Xiao Wang, Sujuan Chen, Dandan Wang, Xixin Zha, Siwen Zheng, Tao Qin, Wenjun Ma, Daxin Peng, Xiufan Liu   +8 more
doaj   +1 more source

Attenuated Porcine Reproductive and Respiratory Syndrome Virus Regains Its Fatal Virulence by Serial Passaging in Pigs or Porcine Alveolar Macrophages To Increase Its Adaptation to Target Cells

Microbiology Spectrum, 2022
Porcine reproductive and respiratory syndrome (PRRS) is a globally important disease threatening the pork industry, and modified live-virus (MLV) vaccines are widely used for its prevention.
Jingjing Wang, Mengsi Zhang, Xiaochun Cui, Xiang Gao, Weifeng Sun, Xinna Ge, Yongning Zhang, Xin Guo, Jun Han, Lei Zhou, Hanchun Yang   +10 more
doaj   +1 more source

Effects of Elevated CO2 and Temperature on Pathogenicity Determinants and Virulence of Potato virus X/Potyvirus-Associated Synergism

Molecular Plant-Microbe Interactions, 2015
Infections of plants by multiple viruses are common in nature and may result in synergisms in pathologies. Several environmental factors influence plant-virus interactions and act on virulence and host defense responses.
Emmanuel Aguilar, Lucía Allende, Francisco J. del Toro, Bong-Nam Chung, Tomás Canto, Francisco Tenllado   +5 more
doaj   +1 more source

Pathogenicity and virulence of Powassan virus

Virulence
Powassan viruses (POWV) are emergent tick-borne Flaviviruses that cause severe encephalitis and long-term neurologic sequelae in patients. POWVs are rapidly spread in the saliva of Ixodes tick species during a 15-minute tick bite. In recent years, there has been an increased incidence of severe POWV disease in the Northeastern United States and ...
Manpreet Kaur, Monica Adam, Megan C. Mladinich   +2 more
openaire   +3 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Different Origins of Newcastle Disease Virus Hemagglutinin-Neuraminidase Protein Modulate the Replication Efficiency and Pathogenicity of the Virus

Frontiers in Microbiology, 2017
To investigate the exact effects of different origins of Newcastle disease virus (NDV) hemagglutinin-neuraminidase (HN) protein to the biological characteristics of the virus, we systematically studied the correlation between the HN protein and NDV ...
Ji-hui Jin, Jin-long Cheng, Zi-rong He, Ying-chao Ren, Xiao-hui Yu, Yang Song, Hui-ming Yang, Yan-ling Yang, Tong Liu, Guo-zhong Zhang, Guo-zhong Zhang   +10 more
doaj   +1 more source

The pathogenicity and virulence of Sindbis virus

Virulence
Sindbis virus (SINV), a widely distributed alphavirus, is both a foundational model for viral replication studies and an underrecognized human pathogen. Despite its typically mild presentation, SINV can lead to prolonged joint pain and, in rare cases, neurological complications. This review explores SINV's molecular biology and clinical manifestations,
Kevin J. Sokoloski, Deepa Karki, Cierra M. Isom, Sayra Moni   +3 more
openaire   +2 more sources