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African Swine Fever Virus Interaction with Host Innate Immune Factors
African swine fever virus (ASFV) adversely affects pig farming owing to its 100% mortality rate. The condition is marked by elevated body temperature, bleeding, and ataxia in domestic pigs, whereas warthogs and ticks remain asymptomatic despite being ...
Ayoola Ebenezer Afe +4 more
doaj +1 more source
The classical swine fever virus (CSFV) particle consists of three glycoproteins, all of which have been shown to be important proteins involved in many virus functions, including interaction with several host proteins. One of these proteins, E2, has been
Elizabeth Vuono +7 more
doaj +1 more source
Determinants of virulence of influenza A virus [PDF]
Influenza A viruses cause yearly seasonal epidemics and occasional global pandemics in humans. In the last century, four human influenza A virus pandemics have occurred. Occasionally, influenza A viruses that circulate in other species cross the species barrier and infect humans. Virus reassortment (i.e. mixing of gene segments of multiple viruses) and
Schrauwen, Eefje +5 more
openaire +2 more sources
Evaluation in Swine of a Recombinant Georgia 2010 African Swine Fever Virus Lacking the I8L Gene
African swine fever virus (ASFV) is the causative agent of African swine fever, a disease currently causing significant economic losses in Europe and Asia. Specifically, the highly virulent ASFV strain Georgia 2010 (ASFV-G) is producing disease outbreaks
Elizabeth Vuono +9 more
doaj +1 more source
Roles of the Polymerase-Associated Protein Genes in Newcastle Disease Virus Virulence [PDF]
Jinlong Cheng +2 more
exaly +2 more sources
Mouse-adapted H9N2 influenza A virus PB2 protein M147L and E627K mutations are critical for high virulence. [PDF]
H9N2 influenza viruses have been circulating worldwide in multiple avian species and have repeatedly infected humans to cause typical disease. The continued avian-to-human interspecies transmission of H9N2 viruses raises concerns about the possibility of
Jingjing Wang +7 more
doaj +1 more source
Background Baculoviruses are significant biocontrol agents of pests in agriculture; however, ultraviolet light B (UV-B) and high temperature inactivate them in the environment within a short time.
Gozde Busra Eroglu, Zihni Demırbag
doaj +1 more source
Functional and structural studies of the vaccinia virus virulence factor N1 reveal a Bcl-2-like anti-apoptotic protein. [PDF]
Vaccinia virus (VACV) encodes many immunomodulatory proteins, including inhibitors of apoptosis and modulators of innate immune signalling. VACV protein N1 is an intracellular homodimer that contributes to virus virulence and was reported to inhibit ...
Abrescia, NGA +12 more
core +1 more source
The Evolutionary Pathway to Virulence of an RNA Virus [PDF]
Paralytic polio once afflicted almost half a million children each year. The attenuated oral polio vaccine (OPV) has enabled world-wide vaccination efforts, which resulted in nearly complete control of the disease. However, poliovirus eradication is hampered globally by epidemics of vaccine-derived polio.
Stern, Adi +8 more
openaire +5 more sources
Adaption of seasonal H1N1 influenza virus in mice. [PDF]
The experimental infection of a mouse lung with influenza A virus has proven to be an invaluable model for studying the mechanisms of viral adaptation and virulence.
Lili Xu +12 more
doaj +1 more source

