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Virus shedding kinetics and unconventional virulence tradeoffs
Tradeoff theory, which postulates that virulence provides both transmission costs and benefits for pathogens, has become widely adopted by the scientific community. Although theoretical literature exploring virulence-tradeoffs is vast, empirical studies validating various assumptions still remain sparse.
Andrew R. Wargo +3 more
openaire +4 more sources
The relationship of within-host multiplication and virulence in a plant-virus system. [PDF]
Virulence does not represent any obvious advantage to parasites. Most models of virulence evolution assume that virulence is an unavoidable consequence of within-host multiplication of parasites, resulting in trade-offs between within-host multiplication
Israel Pagán +2 more
doaj +1 more source
West Nile Virus Infections in (European) Birds [PDF]
West Nile virus (WNV), a member of the Flaviviridae family is an important emerging pathogen transmitted by mosquitoes of the Culex sp . wild-and (peri) domesticated birds act as the natural hosts of WNV.
Barzon, Luisa +2 more
core +1 more source
Molecular basis for a lack of correlation between viral fitness and cell killing capacity. [PDF]
The relationship between parasite fitness and virulence has been the object of experimental and theoretical studies often with conflicting conclusions. Here, we provide direct experimental evidence that viral fitness and virulence, both measured in the ...
Mónica Herrera +4 more
doaj +1 more source
Mutations in the Schmallenberg virus Gc glycoprotein facilitate cellular protein synthesis shutoff and restore pathogenicity of NSs deletion mutants in mice [PDF]
Serial passage of viruses in cell culture has been traditionally used to attenuate virulence and identify determinants of viral pathogenesis. In a previous study, we found that a strain of Schmallenberg virus (SBV) serially passaged in tissue culture ...
Aislynn Taggart +13 more
core +1 more source
Determinants of virulence of influenza A virus [PDF]
Influenza A viruses cause yearly seasonal epidemics and occasional global pandemics in humans. In the last century, four human influenza A virus pandemics have occurred. Occasionally, influenza A viruses that circulate in other species cross the species barrier and infect humans. Virus reassortment (i.e. mixing of gene segments of multiple viruses) and
Schrauwen, Eefje +5 more
openaire +2 more sources
Re-Assembly and Analysis of an Ancient Variola Virus Genome
We report a major improvement to the assembly of published short read sequencing data from an ancient variola virus (VARV) genome by the removal of contig-capping sequencing tags and manual searches for gap-spanning reads. The new assembly, together with
Chad Smithson, Jacob Imbery, Chris Upton
doaj +1 more source
Many of the approximately 165 proteins encoded by the African swine fever virus (ASFV) genome do not have significant similarity to known proteins and have not been studied experimentally. One such protein is DP148R.
A. Reis +6 more
semanticscholar +1 more source
Rift Valley fever virus (RVFV) is a mosquito-borne bunyavirus with a wide host range including ruminants and humans. RVFV outbreaks have had devastating effects on public health and the livestock industry in African countries.
Kaori Terasaki +7 more
doaj +1 more source

