Results 81 to 90 of about 205,339 (347)
Cowpox virus virulence determinants
, 2019 New cowpox virus (CPXV) infections occur naturally in Germany in increasing numbers. It is striking that an infection of the pet rats with these newly occurring CPXV strains often leads to a lethal outcome. Likewise, a CPXV isolate from a pet rat that as well caused human infection in Southern Germany, RatPox09, causes severe disease in Wistar rats ...
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Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay
Advanced Science, EarlyView.This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao +6 more
wiley +1 more source
Evaluation of Virulence in Cynomolgus Macaques Using a Virus Preparation Enriched for the Extracellular Form of Monkeypox Virus [PDF]
, 2022 Eric M. Mucker +10 more
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Advanced Science, EarlyView.This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun +19 more
wiley +1 more source
Veterinary Research, 2020 Non-structural protein 1 (NS1) of influenza virus is a multifunctional protein that plays an important role in virus replication and virulence. In this study, an acetylation modification was identified at the K108 residue of the NS1 protein of H1N1 ...
Jingjiao Ma +8 more
doaj +1 more source
Virulence in murine model shows the existence of two distinct populations of Brazilian Vaccinia virus strains. [PDF]
PLoS ONE, 2008 Brazilian Vaccinia virus had been isolated from sentinel mice, rodents and recently from humans, cows and calves during outbreaks on dairy farms in several rural areas in Brazil, leading to high economic and social impact.
Jaqueline Maria Siqueira Ferreira +13 more
doaj +1 more source
Experimental evidence in support of single host maintenance of a multihost pathogen [PDF]
, 2014 Copyright: 2014 Duffus et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source ...
Duffus, ALJ, Garner, TWJ, Nichols, RA
core +1 more source
Advanced Science, EarlyView.This study analyzes gut bacteria in cholangiocarcinoma patients, revealing distinct microbial signatures that enable accurate disease detection. Species‐based diagnostic models achieved over 98% accuracy in identifying cholangiocarcinoma and distinguished it from other liver diseases. The research demonstrates that specific beneficial bacteria suppress
Benchen Rao +18 more
wiley +1 more source
Molecular determinants of Ebola virus virulence in mice. [PDF]
PLoS Pathogens, 2006 Zaire ebolavirus (ZEBOV) causes severe hemorrhagic fever in humans and nonhuman primates, with fatality rates in humans of up to 90%. The molecular basis for the extreme virulence of ZEBOV remains elusive.
Hideki Ebihara +8 more
doaj +1 more source
Dengue Virus Markers of Virulence and Pathogenicity [PDF]
Future Virology, 2009 The increased spread of dengue fever and its more severe form, dengue hemorrhagic fever, have made the study of the mosquito-borne dengue viruses that cause these diseases a public health priority. Little is known about how or why the four different (serotypes 1-4) dengue viruses cause pathology in humans only, and there have been no animal models of ...
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