Results 51 to 60 of about 1,996,758 (380)

The dual nature of TDC – bridging dendritic and T cells in immunity

FEBS Letters, EarlyView.
TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley   +1 more source

Phenotypic continuum of NFU1‐related disorders

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2025-2035, December 2022., 2022
Abstract Bi‐allelic variants in Iron–Sulfur Cluster Scaffold (NFU1) have previously been associated with multiple mitochondrial dysfunctions syndrome 1 (MMDS1) characterized by early‐onset rapidly fatal leukoencephalopathy. We report 19 affected individuals from 10 independent families with ultra‐rare bi‐allelic NFU1 missense variants associated with a
Rauan Kaiyrzhanov, Maha S. Zaki, Tracy Lau, Sambuddha Sen, Reza Azizimalamiri, Mina Zamani, Gözde Yeşil Sayin, Taru Hilander, Stephanie Efthymiou, Viorica Chelban, Ruth Brown, Kyle Thompson, Maria Irene Scarano, Jaya Ganesh, Kairgali Koneev, Ismail Musab Gülaçar, Richard Person, Dinara Sadykova, Yerdan Maidyrov, Tahereh Seifi, Aizhan Zadagali, Geneviève Bernard, Katrina Allis, Houda Zghal Elloumi, Amanda Lindy, Ehsan Taghiabadi, Sumit Verma, Rachel Logan, Brian Kirmse, Renkui Bai, Shaimaa M. Khalaf, Mohamed S. Abdel‐Hamid, Alireza Sedaghat, Gholamreza Shariati, Mahmoud Issa, Jawaher Zeighami, Hasnaa M. Elbendary, Garry Brown, Robert W. Taylor, Hamid Galehdari, Joseph J. Gleeson, Christopher J. Carroll, James A. Cowan, Andres Moreno‐De‐Luca, Henry Houlden, Reza Maroofian   +45 more
wiley   +1 more source

Prevalence of viral pathogens in a sample of hospitalized Egyptian children with acute lower respiratory tract infections: a two-year prospective study

Bulletin of the National Research Centre, 2022
Background Viral pneumonias are a major cause of childhood mortality. Proper management needs early and accurate diagnosis. This study objective is to investigate the viral etiologies of pneumonia in children.
Amira S. El Refay, Manal A. Shehata, Lobna S. Sherif, Hala G. El Nady, Naglaa Kholoussi, Shams Kholoussi, Nevine R. El Baroudy, Mokhtar R. Gomma, Sara H. Mahmoud, Noura M. Abo Shama, Ola Bagato, Ahmed El Taweel, Ahmed kandeil, Mohamed A. Ali   +13 more
doaj   +1 more source

A Novel Insertion in the Hepatitis B Virus Surface Protein Leading to Hyperglycosylation Causes Diagnostic and Immune Escape

Viruses, 2023
Chronic hepatitis B virus (HBV) infection is a global health threat. Mutations in the surface antigen of HBV (HBsAg) may alter its antigenicity, infectivity, and transmissibility.
Felix Lehmann, Heiko Slanina, Martin Roderfeld, Elke Roeb, Jonel Trebicka, John Ziebuhr, Wolfram H. Gerlich, Christian G. Schüttler, Bernhard Schlevogt, Dieter Glebe   +9 more
doaj   +1 more source

Relationship between latent and rebound viruses in a clinical trial of anti-HIV-1 antibody 3BNC117. [PDF]

, 2018
A clinical trial was performed to evaluate 3BNC117, a potent anti-HIV-1 antibody, in infected individuals during suppressive antiretroviral therapy and subsequent analytical treatment interruption (ATI).
Barton, John P, Belblidia, Shiraz A, Burke, Leah, Butler, Allison L, Caskey, Marina, Cohen, Yehuda Z, Dizon, Juan P, Gulick, Roy M, Jankovic, Mila, Krassnig, Lisa, Lorenzi, Julio CC, Lu, Ching-Lan, Mendoza, Pilar, Millard, Katrina, Nussenzweig, Michel C, Oliveira, Thiago Y, Pai, Joy, Seaman, Michael S, Shimeliovich, Irina, Sleckman, Christopher, Witmer-Pack, Maggi   +20 more
core   +1 more source

Virus satellites drive viral evolution and ecology [PDF]

, 2015
Virus satellites are widespread subcellular entities, present both in eukaryotic and in prokaryotic cells. Their modus vivendi involves parasitism of the life cycle of their inducing helper viruses, which assures their transmission to a new host. However,
Buckling, Angus, Donderis, Jorge, Elena, Santiago F., Frígols, Belén, Marina, Alberto, Mir-Sanchis, Ignacio, Novick, Richard P., Penades, Jose R., Quiles-Puchalt, Nuria   +8 more
core   +1 more source

Leveraging current insights on IL‐10‐producing dendritic cells for developing effective immunotherapeutic approaches

FEBS Letters, EarlyView.
In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali, Gloria Giacomello, Michela Vuono, Silvia Gregori   +3 more
wiley   +1 more source

COVID‐19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis

Annals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1953-1961, December 2022., 2022
Abstract Background The coronavirus disease 2019 (COVID‐19) pandemic has had an unprecedented impact on the healthcare system, economy, and society. Studies have reported that COVID‐19 may cause various neurologic symptoms, including cognitive impairment.
Hanyu Zhang, Zengyuan Zhou
wiley   +1 more source

The alphaviruses: gene expression, replication, and evolution [PDF]

, 1994
The alphaviruses are a genus of 26 enveloped viruses that cause disease in humans and domestic animals. Mosquitoes or other hematophagous arthropods serve as vectors for these viruses.
Strauss, Ellen G., Strauss, James H.
core   +1 more source

The Malaise of the Administrative Process [PDF]

, 1962
Computer viruses uses a few different techniques, with various intentions, toinfect files. However, what most of them have in common is that they wantto avoid detection by anti-malware software.
Arding, Petter, Hedelin, Hugo
core   +3 more sources