Results 121 to 130 of about 309,484 (272)

Advances in the role of intestinal ion channels in the pathogenesis of irritable bowel syndrome [PDF]

Jichu yixue yu linchuang, 2020
Ion channels are widely present in mucous membranes of the digestive tract, their abnormal expression and(or) function are important pathogenic mechanisms of irritable bowel syndrome (IBS).
LAN Fei, LIU Tai-yang, YANG Jie
doaj  

Central control of visceral pain and urinary tract function [PDF]

, 2016
Afferent input from Aδ and C-fibres innervating the urinary bladder are processed differently by the brain, and have different roles in signaling bladder sensation. Aδ fibres that signal bladder filling activate a spino-bulbo-spinal loop, which relays in
Lovick, Thelma
core   +2 more sources

Lactobacillus rhamnosus GG soluble mediators ameliorate early life stress-induced visceral hypersensitivity and changes in spinal cord gene expression

Neuronal Signaling, 2020
Visceral hypersensitivity is a hallmark of many functional and stress-related gastrointestinal disorders, and there is growing evidence that the gut microbiota may play a role in its pathophysiology.
Karen‐Anne McVey Neufeld, C. Strain, M. Pusceddu, R. Waworuntu, Sarmauli Manurung, G. Gross, Gerry M. Moloney, A. Hoban, Kiera Murphy, C. Stanton, T. Dinan, J. Cryan, S. O'Mahony   +12 more
semanticscholar   +1 more source

Paediatric Acute Generalised and Localised Exanthematous Pustulosis: A Systematic Review

JEADV Clinical Practice, EarlyView.
Miranda K. Branyiczky, Megan Lowe, Eric McMullen, Shireen Dumont, Narachai Julanon, Vincent Piguet, Cathryn Sibbald   +6 more
wiley   +1 more source

Psychological and Clinical Factors Mediate Post‐COVID‐19 Irritable Bowel Syndrome

Neurogastroenterology &Motility, EarlyView.
ABSTRACT Background Exposure to COVID‐19 has been shown previously to be associated with a higher risk for irritable bowel syndrome (IBS). This study aimed to better explain this relationship using mediation analysis. Methods This post hoc analysis of a multicenter cohort study includes 623 patients with and without COVID‐19 infection. All participants
Keren Hod, Giovanni Marasco, Luigi Colecchia, Cesare Cremon, Maria Raffaella Barbaro, Giulia Cacciari, Francesca Falangone, Anna Kagramanova, Dmitry Bordin, Vasile Drug, Egidia Miftode, Pietro Fusaroli, Salem Youssef Mohamed, Chiara Ricci, Massimo Bellini, M. Masudur Rahman, Luigi Melcarne, Javier Santos, Beatriz Lobo, Serhat Bor, Suna Yapali, Deniz Akyol, Ferdane Pirincci Sapmaz, Yonca Yilmaz Urun, Tugce Eskazan, Altay Celebi, Huseyin Kacmaz, Berat Ebik, Hatice Cilem Binicier, Mehmet Sait Bugdayci, Munkhtsetseg Banzragch Yağcı, Husnu Pullukcu, Berrin Yalınbas Kaya, Ali Tureyen, İbrahim Hatemi, Elif Sitre Koc, Goktug Sirin, Ali Riza Calıskan, Goksel Bengi, Esra Ergun Alıs, Snezana Lukic, Meri Trajkovska, Dan Dumitrascu, Antonello Pietrangelo, Elena Corradini, Magnus Simren, Jessica Sjolund, Navkiran Tornkvist, Uday C. Ghoshal, Olga Kolokolnikova, Antonio Colecchia, Jordi Serra, Giovanni Maconi, Roberto De Giorgio, Silvio Danese, Piero Portincasa, Antonio Di Sabatino, Marcello Maggio, Elena Philippou, Yeong Yeh Lee, Daniele Salvi, Alessandro Venturi, Claudio Borghi, Marco Zoli, Paolo Gionchetti, Pierluigi Viale, Vincenzo Stanghellini, Giovanni Barbara, on behalf of GI‐COVID19 study group   +68 more
wiley   +1 more source

Precision Lactobacillus reuteri therapy attenuates luminal distention-associated visceral hypersensitivity by inducing peripheral opioid receptors in the colon.

Pain, 2020
Luminal distention and abdominal pain are major clinical hallmarks of obstructive bowel disorders and functional bowel disorders linked to gut dysbiosis.
Shrilakshmi Hegde, You-min Lin, Yu Fu, T. Savidge, Xuan-Zheng Shi   +4 more
semanticscholar   +1 more source

Exploring Associations of Different Types of Childhood Trauma With Symptomatology in Irritable Bowel Syndrome

Neurogastroenterology &Motility, EarlyView.
The current cross‐sectional study aimed to elucidate the impact of different types of childhood trauma on IBS symptomatology. Our findings strongly support the significant role of childhood trauma in IBS pathology and indicate the specific relevance of emotional abuse influencing not only gastrointestinal symptoms but also extraintestinal and ...
Tetyana Bureychak, Jenny Sjödahl, Nawroz Barazanji, Gustav Orell, Olivia Book, Rozalyn Simon, Olga Bednarska, Adriane Icenhour, Susanna Walter   +8 more
wiley   +1 more source

Vaccination of Cattle with the N Terminus of LppQ of Mycoplasma mycoides subsp. mycoides Results in Type III Immune Complex Disease upon Experimental Infection [PDF]

, 2015
Contagious bovine pleuropneumonia (CBPP) is a serious respiratory disease of cattle caused by Mycoplasma mycoides subsp. mycoides. Current vaccines against CBPP induce short-lived immunity and can cause severe postvaccine reactions. Previous studies have
Brown RD, Bygrave A, Churg J, Litamoi J, Provost A, Rawadi G, Thomson GR, Villegas P   +7 more
core   +3 more sources

Beyond Malabsorption: The Need for Symptom‐Based Assessment in Suspected Lactose Intolerance. Lessons From a Test‐Specific Symptom Assessment

Neurogastroenterology &Motility, EarlyView.
Breath test–proven malabsorption does not reliably predict symptoms. Many patients without malabsorption still develop significant symptoms. Symptoms after lactose ingestion are linked to fructose sensitivity and functional GI disorders. Validated, test‐specific symptom assessment is required to identify patients who may benefit from treatment ...
Johann Hammer, Heinz F. Hammer
wiley   +1 more source

Beneficial effect of butyrate‐producing Lachnospiraceae on stress‐induced visceral hypersensitivity in rats

Journal of Gastroenterology and Hepatology, 2018
Emerging evidence indicates that psychological stress is involved in the pathogenesis of irritable bowel syndrome, which is characterized by visceral hypersensitivity and may be accompanied by gut dysbiosis.
Jindong Zhang, Lijin Song, Yujing Wang, Chang Liu, Lu Zhang, Shiwei Zhu, Shuangjiang Liu, L. Duan   +7 more
semanticscholar   +1 more source