Results 91 to 100 of about 195,947 (275)

Integrative proteomic analysis provides novel therapeutic insights for etiological subtypes of diabetes

Diabetes, Obesity and Metabolism, Volume 27, Issue 12, Page 6894-6904, December 2025.
Abstract Aims Type 2 diabetes (T2D) is a highly heterogeneous disease characterised by subtypes with variations in aetiology, disease progression, and risk of complications. However, potential drug targets for these subtypes have not been explored. This study aims to investigate potential drug targets by integrating proteomics.
Jiahe Wei, Hanzhang Wu, Ningjian Wang, Jiahao Zhu, Ranjit Mohan Anjana, Aleksandr V. Sokolov, Helgi B. Schiöth, Viswanathan Mohan, Xiao Tan   +8 more
wiley   +1 more source

Elimination of visceral leishmaniasis in Ethiopia: cross-sector collaboration and cost sharing to promote sustainability

International Journal of Infectious Diseases
Objectives: Sustainable elimination of visceral leishmaniasis as a public health problem requires the contribution of various stakeholders led by the governments.
Duncan Ochol, Kebron Haile, Nathan Onduma, Tsegaye Yohanes, Kimberly Kamara   +4 more
doaj   +1 more source

Infection-adapted emergency hematopoiesis promotes visceral leishmaniasis

PLoS Pathogens, 2017
Cells of the immune system are derived from hematopoietic stem cells (HSCs) residing in the bone marrow. HSCs become activated in response to stress, such as acute infections, which adapt the bone marrow output to the needs of the immune response ...
B. M. Abidin, Akil Hammami, S. Stäger, Krista M. Heinonen   +3 more
semanticscholar   +1 more source

World Association for Veterinary Dermatology Consensus Statement for Diagnosis, and Evidence‐Based Clinical Practice Guidelines for Treatment and Prevention of Canine Leishmaniosis

Veterinary Dermatology, Volume 36, Issue 6, Page 723-787, December 2025.
Hyperkeratosis of (a) the footpads and (b) the nasal planum. ABSTRACT Background Canine leishmaniosis (CanL) due to Leishmania infantum remains common, and veterinarians do not always follow scientifically sound approaches for diagnosis, treatment and prevention. Objectives To provide consensus guidelines for diagnosis and evidence‐based guidelines for
Manolis N. Saridomichelakis, Gad Baneth, Silvia Colombo, Filipe Dantas‐Torres, Lluís Ferrer, Alessandra Fondati, Guadalupe Miró, Laura Ordeix, Domenico Otranto, Chiara Noli   +9 more
wiley   +1 more source

Is Visceral Leishmaniasis the same in HIV-coinfected adults?

Brazilian Journal of Infectious Diseases, 2018
Introduction: Visceral Leishmaniasis is the most severe form of disease caused by the Leishmania donovani complex, with significant morbidity and mortality in developing countries.
Guilherme Alves de Lima Henn, Alberto Novaes Ramos Júnior, Jeová Keny Baima Colares, Lorena Pinho Mendes, João Gabriel Colares Silveira, Anderson Alberto Façanha Lima, Bárbara Pontes Aires, Mônica Cardoso Façanha   +7 more
doaj   +1 more source

Nanoliposomal artemisinin for the treatment of murine visceral leishmaniasis

International Journal of Nanomedicine, 2017
Visceral leishmaniasis (VL) is a fatal, vector-borne disease caused by the intracellular protozoa of the genus Leishmania. Most of the therapeutics for VL are toxic, expensive, or ineffective.
Muzamil Y Want, Mohammad Islammudin, Garima Chouhan, H. Ozbak, H. Hemeg, A. Chattopadhyay, F. Afrin   +6 more
semanticscholar   +1 more source

Leishmaniasis in rheumatoid arthritis

Reumatismo, 2011
Leishmaniasis represents a complex of diseases with an important clinical and epidemiological diversity. Visceral leishmaniasis is of higher priority than cutaneous leishmaniasis as it is a fatal disease in the absence of treatment. The clinical spectrum
M. Cutolo, M.E. Secchi, C. Pizzorni
doaj   +1 more source

Evaluating drug resistance in visceral leishmaniasis: the challenges

Parasitology, 2016
SUMMARY For decades antimonials were the drugs of choice for the treatment of visceral leishmaniasis (VL), but the recent emergence of resistance has made them redundant as first-line therapy in the endemic VL region in the Indian subcontinent.
S. Hendrickx, Philippe J. Guerin, G. Caljon, S. Croft, L. Maes   +4 more
semanticscholar   +1 more source

Assessment of Renal Functions and Lesions in Dogs with Serological Diagnosis of Canine Visceral Leishmaniasis [PDF]

, 2020
Niara Vanat Nadal, Sabrina Destri Emmerick Campos, Estella Francisco de Azevedo, Artur Augusto Velho Mendes, Fabiano Borges Figueiredo, Daniel de Barros Macieira, Maurício Afonso Verícimo, Nádia Regina Pereira Almosny   +7 more
openalex   +1 more source

Epidemiology of canine visceral leishmaniasis in a vulnerable region in Brazil [PDF]

, 2021
Douglas Aparecido da Silva, Natália Camila Minucci Bonatto, Gabriela Lovizutto Venturin, Larissa Martins Melo, Paula Lima de Oliveira, Letícia Ramos Costa, Maria Rachel Melo Bosculo, Luiz Daniel de Barros, Valéria Marçal Felix de Lima, Breno Fernando Martins de Almeida   +9 more
openalex   +1 more source