Antileishmanial Activities of Carvacrol Nanoencapsulate in Biopolymeric Nanoparticles
Visceral leishmaniasis (VL) is a neglected parasitic disease, and the first‐line treatments for VL include drugs that exhibit serious toxicological issues. In this sense, new molecules are sought for VL treatment, such as Carvacrol (Car), a phenolic monoterpene that has shown strong activity against Leishmania spp.
Joyce Cordeiro Borges+6 more
wiley +1 more source
Genetic variations in the host TLRs genes play an important role in susceptibility and/or resistance to visceral leishmaniasis by altering the host-pathogen interaction.
Abhishek Mandal+5 more
doaj +1 more source
Affective Role of the Future Autonomous Vehicle Interior [PDF]
Recent advancements in autonomous technology allow for new opportunities in vehicle interior design. Such a shift in in-vehicle activity suggests vehicle interior spaces should provide an adequate manner by considering users' affective desires. Therefore, this study aims to investigate the affective role of future vehicle interiors.
arxiv
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
Leishmaniasis in Patients With Inflammatory Bowel Disease: A National Multicenter Study of GETECCU
ABSTRACT Background Leishmaniasis (LI) is a vector‐borne illness caused by a protozoan of the genus Leishmania. Data on the features of LI in patients with inflammatory bowel disease (IBD) are scarce. Aim To describe the characteristics of patients with IBD who present with leishmaniasis, infection outcomes and the risk factors associated with ...
L Madero‐Velázquez+29 more
wiley +1 more source
Transient superdiffusion and long-range correlations in the motility patterns of trypanosomatid flagellate protozoa [PDF]
We report on a diffusive analysis of the motion of flagellate protozoa species. These parasites are the etiological agents of neglected tropical diseases: leishmaniasis caused by Leishmania amazonensis and Leishmania braziliensis, African sleeping sickness caused by Trypanosoma brucei, and Chagas disease caused by Trypanosoma cruzi.
arxiv +1 more source
Visceral leishmaniasis patients display altered composition and maturity of neutrophils as well as impaired neutrophil effector functions [PDF]
Immunologically, active visceral leishmaniasis (VL) is characterised by profound immunosuppression, severe systemic inflammatory responses and an impaired capacity to control parasite replication.
Adem, E+19 more
core +3 more sources
Kidney involvement in leishmaniasis—a review
Leishmaniasis is an infectious disease caused by protozoa of the genus Leishmania transmitted by insects of the genus Lutzomyia sp. or Phlebotomus sp.
Geraldo Bezerra da Silva Junior+2 more
doaj
Leishmaniasis is a tropical infection caused by the protozoan, belonging to the group of Leishmania which causes Old World and New World disease. These are typically divided into cutaneous, mucocutaneous, visceral, viscerotropic, and disseminated disease.
Cyriac Abby Philips+4 more
doaj +1 more source
Risk factors for in-hospital mortality of visceral leishmaniasis patients in eastern Uganda. [PDF]
OBJECTIVE: To identify risk factors for in-hospital mortality in patients treated for visceral leishmaniasis (VL) in Uganda. METHODS: Retrospective analysis of VL patients' clinical data collected for project monitoring by Médecins Sans Frontières in ...
Bern+20 more
core +3 more sources