Results 171 to 180 of about 666,764 (304)

Advances in the Protective Effects and Mechanisms of β‐Aminoisobutyric Acid in Maintaining Multi‐Organ Homeostasis

open access: yesMedicine Bulletin, EarlyView.
ABSTRACT β‐Aminoisobutyric acid (BAIBA) is an exercise‐responsive myokine/metabolite released by skeletal muscle and has attracted increasing interest as a potential exercise mimetic and therapeutic candidate in preclinical research. BAIBA acts locally in skeletal muscle and can also reach distal organs through the circulation, contributing to the ...
Hao‐Zhe Wang   +5 more
wiley   +1 more source

Transforming Musculoskeletal Disorder Management With Multimodal AI Platform for Early Diagnosis, Self‐Screening, and Personalized Care

open access: yesMed Research, EarlyView.
We developed a multimodal large language model‐enabled framework for the early detection, self‐screening, and personalized management of major musculoskeletal disorders, including osteoarthritis (OA), rheumatoid arthritis (RA), and osteoporosis (OP).
Pengyuan Xu   +32 more
wiley   +1 more source

Lifestyle mediates the association between normal-weight visceral obesity and MASLD in older adults with hypertension and diabetes. [PDF]

open access: yesFront Nutr
Xi JY   +15 more
europepmc   +1 more source

Proteomic Signatures of Ectopic Fat Distribution: Tissue‐Specific Drivers and Clinical Implications

open access: yesMed Research, EarlyView.
Integration of plasma proteomics and multi‐organ MRI in 666 UK Biobank participants, combined with a knockoff‐based causal inference and machine learning framework, reveals organ‐specific drivers of ectopic fat: PLA2G1B (pancreas), ERBB2/IGFBP2 (liver), CA14 (muscle), and NCAM2/TNFRSF10B (pericardium). These drivers engage distinct pathways (e.g., PI3K‐
Bing Zhang   +9 more
wiley   +1 more source

Beyond Joint Hypermobility: Investigating Bladder Dysfunction in Hypermobile Ehlers‐Danlos Syndrome

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Introduction and Objectives Hypermobile Ehlers‐Danlos Syndrome (hEDS) is the most common subtype of Ehlers‐Danlos Syndrome, a group of connective tissue disorders caused by collagen abnormalities. While musculoskeletal features of hEDS are well characterized, its impact on visceral organs, including the bladder, remains underexplored.
Marium Ansari   +5 more
wiley   +1 more source

One Size Does Not Fit All: Establishing Anticipated Baseline Intravesical Pressures Adjusted for Position and Body Mass Index

open access: yesNeurourology and Urodynamics, EarlyView.
ABSTRACT Purpose Accurate measurement of intravesical pressure (Pves) during multichannel urodynamic testing requires zeroing with reference to surrounding atmosphere, establishing a reference level for measuring Pves, and assessing response to coughs.
Parker Holum   +6 more
wiley   +1 more source

Visceral obesity is not an independent risk factor of mortality in subjects over 65 years

open access: yes, 2013
Frédérique Thomas,1 Bruno Pannier,1 Athanase Benetos,2 Ulrich M Vischer3,† 1Centre d'Investigations Préventives et Cliniques, Paris, France; 2Department of Geriatrics, Nancy University Hospital Center, University of ...
Benetos A   +3 more
core  

Impact of a low‐carbohydrate diet on cardiometabolic parameters in individuals with and without diabetes: An 8‐year longitudinal study within the ELSA‐Brasil cohort

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Low‐carbohydrate diets (LCDs) are widely adopted for metabolic management, but their long‐term cardiometabolic effects in diverse populations remain unclear. We aimed to evaluate the association between self‐selected moderate LCD adherence and cardiometabolic parameters in individuals with and without diabetes.
Leticia Batista de Azevedo   +3 more
wiley   +1 more source

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