Results 181 to 190 of about 666,764 (304)

A proposal for individualized administration of energy and protein in the critically ill with obesity

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract The increasing prevalence of obesity has transformed intensive care and nutritional therapy of patients with obesity from a specialized problem to standard care. The dilemma in providing nutrition to critically ill patients with obesity is that current and historical nutritional guideline recommendations are based on expert opinion, are ...
K. Georg Kreymann   +2 more
wiley   +1 more source

Beyond BMI: Genome‐Wide Associations of Visceral Fat, Fat Mass, and Fat‐Free Mass in Eastern Asian Populations

open access: yesObesity, EarlyView.
ABSTRACT Objective BMI is widely used to define obesity and may not capture heterogeneity in body fat distribution. Genetic studies of obesity have largely focused on BMI but not visceral fat and fat‐free mass, which is particularly limited in East Asian populations.
Hsin‐Ming Lu   +5 more
wiley   +1 more source

Trends of Obesity in Early Adulthood and Later Adulthood Across 196 Countries and Territories, 1990–2022

open access: yesObesity, EarlyView.
ABSTRACT Objective We aimed to understand the global burden of obesity in early adulthood and later adulthood over the past three decades. Methods We analyzed obesity prevalence across 196 countries/territories from 1990 to 2022 for early adulthood (age 20–49 years) and later adulthood (age ≥ 50 years) using the Non‐Communicable Disease Risk Factor ...
Abdiwahab M. Ali   +2 more
wiley   +1 more source

Divergent Obesity Classification Between the Edmonton Obesity Staging System and the Lancet Commission Model

open access: yesObesity, EarlyView.
ABSTRACT Objective BMI alone does not capture obesity‐related health heterogeneity. The Edmonton Obesity Staging System (EOSS) grades obesity severity based on comorbidities and functional impairment, whereas the Lancet Commission Diagnostic Model for Obesity (DMO) distinguishes preclinical from clinical obesity based on organ dysfunction.
Tobias Hagemann   +3 more
wiley   +1 more source

The role of tryptophan hydroxylase‐1 in metabolic dysfunction‐associated steatotic liver disease

open access: yesPediatric Investigation, EarlyView.
Silencing hepatic tryptophan hydroxylase 1 (TPH1) alleviated diet‐induced steatotic liver disease by reducing lipid accumulation, oxidative stress, inflammation, fibrosis, and hepatocyte apoptosis. These protective effects were mediated, at least in part, through restoration of Parkin‐dependent mitochondrial autophagy, identifying hepatic TPH1 as a ...
Shuangzhen Jia   +3 more
wiley   +1 more source

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