Results 81 to 90 of about 666,764 (304)

Generalised and abdominal obesity and risk of diabetes, hypertension and hypertension–diabetes co-morbidity in England [PDF]

, 2008
Objectives To look at trends in generalised (body mass index (BMI) ≥30 kg m–2) and abdominal (waist circumference (WC) >102 cm in men, >88 cm in women) obesity among adults between 1993 and 2003, and to evaluate their association with diabetes ...
Hirani, V., Zaninotto, P., Primatesta, P.   +2 more
core  

In Silico to In Cerebro—Development of the Orexin Receptor Antagonist “Photorexant” for Photomodulation In Vitro and in Mouse Brains

Angewandte Chemie International Edition, EarlyView.
Following a structure‐based design approach, photoswitchable derivatives of the FDA‐approved drug suvorexant were designed, docked, synthesized, and characterized pharmacologically at the orexin 1 and 2 receptors (OX1R and OX2R). Optimized “photorexant” showed up to an 11‐fold difference in IC50 between photoisomers, enabled dynamic and reversible ...
Marcus Angermann, Marie H. Deventer, Vicente Ledesma‐Martin, Nuno Martinho, Alix Flake, Silvia Mori, Angel Nuñez, Jaime Pignatelli, Rita C. Guedes, Christophe P. Stove, Michael Decker   +10 more
wiley   +1 more source

Prevalence of sarcopenia and sarcopenic obesity in Korean adults: The Korean Sarcopenic Obesity Study (KSOS) [PDF]

, 2009
*Context:* Sarcopenic obesity (SO), a combination of excess weight and reduced muscle mass and/or strength, is suggested to be associated with an increased risk of adverse health outcomes.
Tae Nyun Kim, Sei Hyun Baik, Hyun Joo Kang, Sae Jeong Yang, Wook Song, Ji A Seo, Sin Gon Kim, Hye Jin Yoo, Nan Hee Kim, Kang Il Lim, Kyung Mook Choi, Dong Seop Choi   +11 more
core  

Revisiting paravertebral muscles in European rabbits (Oryctolagus cuniculus) and European brown hares (Lepus europaeus) (Leporidae; Lagomorpha)

The Anatomical Record, EarlyView.
Abstract Domesticated European rabbits (Oryctolagus cuniculus) have long been chosen as laboratory model organisms. Despite this, there has been no definitive study of the vertebral musculature of wild rabbits. Relevant descriptions of well‐studied veterinary model mammals (such as dogs) are generally applicable, but not appropriate for a species ...
Nuttakorn Taewcharoen, Emma Sherratt, Philip Stott, Rachel Norris   +3 more
wiley   +1 more source

Bitemporal Obesity: An Overlooked Sign of Visceral Obesity?

Cureus, 2022
With increasing rates of morbidity and mortality associated with visceral obesity, as well as its related cardiometabolic disorders, physical findings that aid in diagnosing patients at risk for such conditions are extremely useful. This brief report introduces the novel facial physical sign of bitemporal obesity, which the author observed in a patient
openaire   +2 more sources

Human evolution and the obstetrical dilemma: The pelvic floor hypothesis

The Anatomical Record, EarlyView.
Abstract Human childbirth is mechanically difficult because a large‐headed, broad‐shouldered fetus must pass through a comparatively narrow, twisted bony birth canal. Traditional explanations of this “obstetrical dilemma” emphasize the role of bipedal locomotion in inhibiting the evolution of a wider, more spacious pelvis.
Barbara Fischer, Ekaterina Stansfield
wiley   +1 more source

Adipocytes Directly Affect Coronary Artery Disease Pathogenesis via Induction of Adipokine and Cytokine Imbalances

Frontiers in Immunology, 2019
This study aimed to investigate the adipokine and cytokine profiles of adipocytes from epicardial and subcutaneous adipose tissues in interconnection with the visceral adipose tissue area and the biochemical and clinical characteristics of patients with ...
Olga Gruzdeva, Olga Gruzdeva, Evgenya Uchasova, Yulia Dyleva, Daria Borodkina, Olga Akbasheva, Larisa Antonova, Vera Matveeva, Ekaterina Belik, Sergei Ivanov, Anton Sotnikov, Kirill Kozyrin, Natalia Brel, Maxim Sinitsky, Victoria Karetnikova, Victoria Karetnikova, Alexander Kokov, Evgenya Bychkova, Tamara Pecherina, Olga Barbarash, Olga Barbarash   +20 more
doaj   +1 more source

Hip Arthroscopy in Adults Aged 40 or Older Produces Clinically Meaningful Symptom Improvement but Carries a Substantial Risk of Conversion to Total Hip Arthroplasty: A Systematic Review

Arthroscopy, EarlyView.
Purpose To report conversion rates to total hip arthroplasty (THA), patient‐reported outcome measures, and complication rates in adults aged ≥ 40 years undergoing hip arthroscopy since 2016. Methods MEDLINE, EMBASE, and PubMed were searched from January 2016 to March 2025, and pertinent data were abstracted from eligible studies according to the ...
Helena Son, Benjamin Blackman, Joshua Dworsky‐Fried, Dan Cohen, Yoan Bourgeault‐Gagnon, Axel Öhlin, Nicole Simunovic, Iqbal Multani, Tyler M. Hauer, Craig S. Mauro, Olufemi Ayeni   +10 more
wiley   +1 more source

An Overview on Visceral Obesity

, 2023
Faculty Mentor: Mindy KurzerObesity is one of the most prevalent chronic conditions affecting nearly forty-percent of the world. However, obesity affects individuals in different manners, oftentimes in localized regions in the body.
Mohran, Yasmin
core  

Dissecting the dissection laboratory: Elements for designing a human anatomy laboratory

Anatomical Sciences Education, EarlyView.
Abstract The human anatomy dissection laboratory is a critical component of anatomical and medical education. Development, maintenance, and stocking of these laboratory spaces have unique demands, with all of the challenges in running a laboratory with Biosafety Laboratory Level 2 (BSL‐2) classification, housing a large volume of tissues saturated with
Rhiannon E. Robinson, Abbey Breckling, Danielle N. Edwards, Nicole Geske, Burhan Gharaibeh, Bobbie J. Leeper, Molly Ostwald, Mary Schilling, Bridgett Severt, Kelsey Stevens, J. P. Swigart, Jonathan J. Wisco, Melissa Zolnierz, Jeremy J. Grachan   +13 more
wiley   +1 more source