Results 81 to 90 of about 5,401 (177)
Treatment of Basal Cell Carcinoma with Vismodegib
, 2019 The most prevalent nonmelanoma skin cancers are basal cell carcinoma (BCC) and locally advanced basal cell carcinoma (aBCC). Current, effective first-line treatments for BCC aim to remove and destroy cancerous skin cells through excision surgery, Mohs ...
Chrissobolis, Sophocles +5 more
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Cutaneous Basal Cell Carcinoma with Lymph Node and Pulmonary Metastases
Case Reports in Oncological Medicine, 2018 Basal cell carcinoma (BCC) is the most common skin cancer. Metastatic BCC is an extraordinary rare finding observed in only 0.5% of all cases. Until the introduction of the small molecule hedgehog inhibitor vismodegib, patients with metastatic BCC were ...
Renate U. Wahl +2 more
doaj +1 more source
, 2017 Zoe Apalla,1 Chrysoula Papageorgiou,1 Aimilios Lallas,1 Elena Sotiriou,1 Elizabeth Lazaridou,1 Efstratios Vakirlis,1 Athanassios Kyrgidis,2 Demetrios Ioannides1 1First Department of Dermatology, Aristotle University, 2Department of Oral and Maxillofacial
Ioannides D +7 more
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Antagonizing the hedgehog pathway with vismodegib impairs malignant pleural mesothelioma growth in vivo by affecting stroma [PDF]
, 2016 An autocrine driven upregulation of the Hedgehog (Hh) signaling pathway has been described in malignant pleural mesothelioma (MPM), in which the ligand, desert hedgehog (DHH), was produced from tumor cells. However, our investigation revealed that the Hh
Arni, Stephan +11 more
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Vismodegib: A smoothened inhibitor for the treatment of advanced basal cell carcinoma
Indian Dermatology Online Journal, 2013 Incidence of basal cell carcinoma (BCC), the most common skin cancer in humans, is rising. Surgery is the mainstay of treatment but there is no standard of care for locally advanced or metastatic disease. Hedgehog signaling proteins are critical for cell
Suruchi Aditya, Aditya Rattan
doaj +1 more source
Vismodegib for advanced basal cell carcinoma treatment
, 2017 Trabalho de Projeto do Mestrado Integrado em Medicina apresentado à Faculdade de MedicinaO carcinoma basocelular é a neoplasia humana mais frequente e a sua incidência tem aumentado mundialmente.
Xavier, Marta Martins
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Dysgeusia and weight loss under treatment with vismodegib: benefit of nutritional management
, 2016 International audiencePurpose Whereas vismodegib is effective in the treatment of locally advanced/metastatic basal cell carcinoma, dysgeusia and weight loss are common side effects of such treatment.
Le Moigne, Marie +9 more
core +1 more source
, 2017 Retreatment with vismodegib in advanced basal cell carcinoma (BCC) patients who previously discontinued the drug due to disease progression (PD) has not been reported yet.
Cristiana Bergamini +11 more
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Case Reports in Dermatological Medicine, 2018 We present a case report of a male with multifocal and extensive basal cell carcinoma. Due to extremely large size and deep tumor infiltration, he was not a surgical candidate.
Abigail I. Franco +5 more
doaj +1 more source
BACKGROUND: Systemically delivered hedgehog inhibitors including vismodegib and sonidegib are widely used to treat basal cell carcinomas (BCCs). Ablative fractional laser (AFL)-assisted topical delivery of vismodegib has been demonstrated in preclinical ...
Pedersen, Kristian Kåber +8 more
core +1 more source