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AZT inhibits Visna/maedi virus -induced apoptosis
Archives of Virology, 2004Visna/maedi virus (VMV) causes severe encephalitis and a progressive demyelinating disease in sheep. Previous in vitro studies have demonstrated that VMV-infection leads to apoptosis in sheep choroid plexus cells (SCPC) via induction of both intrinsic and extrinsic pathways with subsequent activation of caspases.
Bellet, V. +4 more
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Visna/maedi virus-induced apoptosis involves the intrinsic mitochondrial pathway
Archives of Virology, 2004Visna/maedi virus (VMV) infection in sheep choroid plexus cells was associated with the appearance of apoptosis and the implication of a caspase-dependent mechanism. Sheep choroid plexus cells were mock-infected or infected with VMV to examine the time course of activation of the intrinsic pathway of apoptosis.
V, Bellet, S, Delebassée, C, Bosgiraud
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Association of TMEM154 variants with visna/maedi virus infection in Turkish sheep
Small Ruminant Research, 2019Abstract Visna/maedi (VM) is a multisystemic disease of sheep characterized by persistent lentiviral infection, slow progression and eventually death. The VM virus (VMV) affects sheep throughout the world and is the focus of national eradication campaigns.
ÖNER, YASEMİN +13 more
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Ovine aortic smooth muscle cells allow the replication of visna-maedi virus in vitro
Archives of Virology, 1995Visna-maedi virus induces in sheep an interstitial lung disease characterised by an accumulation of smooth muscle cells (SMC) or myomatosis. Infection by HIV-1 has been recently associated with disorders of the vessel-derived cells: primary pulmonary hypertension, coronary artery disease and smooth muscle tumors in humans. We hypothesized that, besides
Leroux, C. +8 more
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La pathogenese du virus Visna-Maedi : modèle expérimental pour l'étude des Lentivirinae
Médecine et Maladies Infectieuses, 1987Resume La pathogenese des Lentivirinae est liee a l'ambiguite pathologique des maladies progressives, lentes, causees par des Retrovirus non oncogenes. Le tropisme de ces virus pour certaines cellules, macrophages pour le Visna-Maedi, CAEV et AIEV, lymphocytes pour le HIV, est du a la presence de recepteurs cellulaires. La maturation ou stimulation
C. Bosgiraud +2 more
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Comparative Immunology, Microbiology and Infectious Diseases, 2012
The small ruminant lentiviruses include the prototype for the genus, visna-maedi virus (VMV) as well as caprine arthritis encephalitis virus (CAEV). Infection of sheep or goats with these viruses causes slow, progressive, inflammatory pathology in many tissues, but the most common clinical signs result from pathology in the lung, mammary gland, central
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The small ruminant lentiviruses include the prototype for the genus, visna-maedi virus (VMV) as well as caprine arthritis encephalitis virus (CAEV). Infection of sheep or goats with these viruses causes slow, progressive, inflammatory pathology in many tissues, but the most common clinical signs result from pathology in the lung, mammary gland, central
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Virus Research, 1999
Maedi visna (MV) and caprine arthritis-encephalitis (CAE) are two retroviral infections distributed world wide. Antigenic cross reactions between the viruses have been demonstrated in gag and env encoded structural proteins. Antigens from ovine lentiviruses are easier to produce in cell culture systems and therefore have been used in the development of
ROSATI, Sergio +3 more
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Maedi visna (MV) and caprine arthritis-encephalitis (CAE) are two retroviral infections distributed world wide. Antigenic cross reactions between the viruses have been demonstrated in gag and env encoded structural proteins. Antigens from ovine lentiviruses are easier to produce in cell culture systems and therefore have been used in the development of
ROSATI, Sergio +3 more
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Early events in the experimental interstitial lung disease induced in sheep by the Visna-maedi virus
Immunology Letters, 1993Visna-maedi virus is a lentivirus closely related to the human immunodeficiency virus type I (HIV-I). During spontaneous infection of sheep by Visna-maedi virus an interstitial lung disease is observed. It is characterized by an alveolitis, peribronchovascular lymphoid nodules, alveolar wall thickening and myomatosis. In order to decipher the pathology
Cadore, J.L. +9 more
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Isolation of visna-maedi virus from the choroid plexus of an apparently healthy sheep in Italy
Veterinary Research Communications, 1985In this paper, the presence of visna-maedi in Italy, reported to exist since 1982 on clinical grounds, and the presence of anti-visna-maedi antibody is confirmed by the isolation of the viral agent from choroid plexus cells of an apparently healthy sheep.
V P, Caporale, R, Lelli, D, Rutili
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[Detection of visna-maedi virus antibodies and antigens by immunoblotting].
Annales de recherches veterinaires. Annals of veterinary research, 1989The visna-maedi virus was immunologically diagnosed using an immunoblotting technique from an antigenic preparation of the visna-maedi virus K796 purified by sucrose density gradient centrifugation. After SDS-PAGE electrophoresis and transfer onto a nitrocellulose sheet, the immunoblotting procedure was adapted to the search for specific antibodies in ...
C, Bosgiraud +6 more
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