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Biology and Pathogenesis of Lentiviruses
Journal of General Virology, 1989 Lentiviruses are a family of retroviruses linked by similarities in genetic composition, molecular mechanisms of replication and in biological interactions with their hosts. They are best known as agents of slow disease syndromes that begin insidiously after prolonged periods of subclinical infection and progress slowly leading to the degeneration of ...
O Narayan, J E Clements
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Comparative Analysis of Tat-Dependent and Tat-Deficient Natural Lentiviruses
Veterinary Sciences, 2015 The emergence of human immunodeficiency virus (HIV) causing acquired immunodeficiency syndrome (AIDS) in infected humans has resulted in a global pandemic that has killed millions. HIV-1 and HIV-2 belong to the lentivirus genus of the Retroviridae family.
Deepanwita Bose +2 more
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Distinct MCM10 Proteasomal Degradation Profiles by Primate Lentiviruses Vpr Proteins
Viruses, 2020 Viral protein R (Vpr) is an accessory protein found in various primate lentiviruses, including human immunodeficiency viruses type 1 and 2 (HIV-1 and HIV-2) as well as simian immunodeficiency viruses (SIVs).
Chieh-Wen Lo +2 more
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Immunization against Small Ruminant Lentiviruses [PDF]
Viruses, 2013 Multisystemic disease caused by Small Ruminant Lentiviruses (SRLV) in sheep and goats leads to production losses, to the detriment of animal health and welfare.
Beatriz Amorena +2 more
doaj +6 more sources
Microbiology Spectrum, 2023 FAM46C is a multiple myeloma (MM) tumor suppressor whose function is only starting to be elucidated. We recently showed that in MM cells FAM46C triggers apoptosis by inhibiting autophagy and altering intracellular trafficking and protein secretion.
Marilena Mancino +12 more
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Exploiting a rodent cell block for intrinsic resistance to HIV-1 gene expression in human T cells
mBio, 2023 HIV-1 virion production is inefficient in cells derived from mice and other rodents reflecting cell-intrinsic defects to interactions between the HIV-1 auxiliary proteins Tat and Rev and host dependency factors CCNT1 (Cyclin T1) and XPO1 (exportin-1 ...
Ryan T. Behrens +10 more
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Microbiology Spectrum, 2022 HIV-1 must package its RNA genome to generate infectious viruses. Recent studies have revealed that during genome packaging, HIV-1 not only excludes cellular mRNAs, but also distinguishes among full-length viral RNAs. Using NL4-3 and MAL molecular clones,
Jonathan M. O. Rawson +5 more
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Pathogens, 2023 Small ruminant lentiviruses (SRLVs) are transmitted among ovine and caprine species. This disease is a severe problem for small ruminant production, not only for animals’ well-being but also for flocks’ efficiency.
João Jacob-Ferreira +4 more
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mBio, 2020 Lentiviral DNA integration favors transcriptionally active chromatin. We previously showed that the interaction of human immunodeficiency virus type 1 (HIV-1) capsid with cleavage and polyadenylation specificity factor 6 (CPSF6) localizes viral ...
Wen Li +13 more
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Common mechanism of infection by lentiviruses [PDF]
Nature, 1997 No abstract available.
Willett, B.J. +4 more
openaire +3 more sources