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Veterinary Record, 1980
A brief history of the occurrence of maedi/visna or maedi/visna related diseases is given. The clinical features and diagnosis are described. Recent experimental work performed in an attempt to resolve the pathogenetic features of slowness and persistence of infection, characteristic of maedi/visna, is covered.
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A brief history of the occurrence of maedi/visna or maedi/visna related diseases is given. The clinical features and diagnosis are described. Recent experimental work performed in an attempt to resolve the pathogenetic features of slowness and persistence of infection, characteristic of maedi/visna, is covered.
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Antigenic variation in visna virus
Cell, 1979Two antigenic variants of visna virus were isolated sequentially from a single sheep inoculated with a plaque-purified strain of virus designated 1514. The genetically stable variants, LV1-1 and LV1-4, are of two classes: LV1-1 is partially neutralized by antibody to the inoculum strain 1514, while LV1-4 is not neutralized by antibody to 1514.
J V, Scott +4 more
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Veterinary Record, 1987
In most cases, maedi-visna virus infection is characterised by a subclinical, persistent virus-carrier state. However, in heavily infected flocks, economically significant disease does occur, mainly apparent as ill-thrift and chronic respiratory disease (maedi) in older ewes and as an indurative mastitis, which can result in delayed weight gain of ...
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In most cases, maedi-visna virus infection is characterised by a subclinical, persistent virus-carrier state. However, in heavily infected flocks, economically significant disease does occur, mainly apparent as ill-thrift and chronic respiratory disease (maedi) in older ewes and as an indurative mastitis, which can result in delayed weight gain of ...
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Resistance of Visna Virus to Interferon
Journal of Infectious Diseases, 1978Visna is a slow infection of sheep caused by a retrovirus. The persistence of virus despite the immune response of the host is best explained by restricted genetic expression of the virus and consequently prolonged periods of residence inside cells.
D, Carroll +5 more
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1987
Visna, the prototype of slow infections (Sigurdsson, 1954), is a menin-goencephalitis of sheep, caused by a retrovirus (Petursson et al., 1979) which belongs to the group of lentiviruses and is related to the recently isolated human virus that causes AIDS (Sonigo et al., 1985).
G. Georgsson +2 more
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Visna, the prototype of slow infections (Sigurdsson, 1954), is a menin-goencephalitis of sheep, caused by a retrovirus (Petursson et al., 1979) which belongs to the group of lentiviruses and is related to the recently isolated human virus that causes AIDS (Sonigo et al., 1985).
G. Georgsson +2 more
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Characterization of visna virus mRNA
Journal of Virology, 1979Visna virus is a retrovirus responsible for a classical slow infection of the central nervous system of sheep. In the present work we focused our attention on the viral mRNA's. We found that, during the acute infection in vitro, (i) viral mRNA's amount to only 0.1% of the total cytoplasmic RNA, (ii) 20% of the total cytoplasmic viral RNA is found in ...
P, Filippi +3 more
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Infectivity of visna virus DNA
Virology, 1976Abstract Deoxyribonucleic acid isolated from cells infected with the RNA containing slow virus visna confers on uninfected cells the capacity to synthesize new virus. The cytopathic agent isolated in these experiments has the biological and biochemical properties of visna virus, and the active material is DNA by several criteria, the most important ...
A T, Haase +3 more
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Journal of Virology, 1977
Visna is a classical slow infection in which virus characteristically persists in the face of the host immune response. The agent of this disease belongs to the retravirus group. The persistence of infection and the slow spread of virus are at least in part a consequence of restriction of the expression of virus genetic information in tissues of an ...
M, Brahic +3 more
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Visna is a classical slow infection in which virus characteristically persists in the face of the host immune response. The agent of this disease belongs to the retravirus group. The persistence of infection and the slow spread of virus are at least in part a consequence of restriction of the expression of virus genetic information in tissues of an ...
M, Brahic +3 more
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Goat visna virus: Isolation of a retrovirus related to visna virus of sheep
Archives of Virology, 1981Choroid plexus (GCP-3) cell cultures were prepared from an adult goat with symptoms of visna. The GCP-3 cell layer had partly fused into large multinucleated giant cells and electronmicrographs showed virus particles morphologically indistinguishable from sheep visna virus (SVV).
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1979
In 1935 the first cases of a previously unknown paralytic disease were seen in older age-groups of sheep in a south-western region of Iceland (Fig l). From 1935-1952 cases were increasing causing considerable loss of sheep in the affected flocks (l, 2, 3).
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In 1935 the first cases of a previously unknown paralytic disease were seen in older age-groups of sheep in a south-western region of Iceland (Fig l). From 1935-1952 cases were increasing causing considerable loss of sheep in the affected flocks (l, 2, 3).
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