Results 71 to 80 of about 2,319,781 (255)

Additively Manufactured Geometry‐Reconfigurable Soft Neural Probes With Monolithic Multifunctionality

open access: yesAdvanced Functional Materials, EarlyView.
A geometry‐reconfigured additive manufacturing strategy converts planar printed soft materials into soft compact neural probes with integrated hydrogel electrodes and microfluidic channels. The resulting NeuroMAP platform enables scalable multichannel recording, localized chemical delivery, stable in vivo electrophysiological recording, and reduced ...
Hyunjin Lee   +15 more
wiley   +1 more source

Physiological basis of resolution acuity in vision

open access: yesNature Communications
Vision is the primary sensory modality for many animals, especially humans and other primates. A fundamental constraint on visual resolution acuity is set by the size and spacing of cone photoreceptors, notably in the fovea of the retina where cones are ...
Keaton M. Ramsey   +5 more
doaj   +1 more source

Defect‐Mediated Inelastic Light Scattering by Infrared Phonons in Hexagonal Boron Nitride

open access: yesAdvanced Functional Materials, EarlyView.
Optically active defects in hexagonal boron nitride enable inelastic stimulated light scattering mediated by infrared‐active phonons, relaxing conventional Raman selection rules. Defect engineering enhances the Stokes‐conversion process and activates both TO‐ and LO‐phonon scattering channels.
Prabhdeep Singh   +4 more
wiley   +1 more source

Human foveal cone photoreceptor topography and its dependence on eye length

open access: yeseLife, 2019
We provide the first measures of foveal cone density as a function of axial length in living eyes and discuss the physical and visual implications of our findings.
Yiyi Wang   +5 more
doaj   +1 more source

Beyond Thin Film Limits—Superhard and Hydrogen‐Free Amorphous Carbon Coatings With Over 100 µm Thickness

open access: yesAdvanced Functional Materials, EarlyView.
For the first time, an extreme‐thick laser‐arc PVD ta‐C (DLC) coating exceeding 100 µm is demonstrated, opening up new possibilities for ultra‐high load bearing capacity. This superhard amorphous carbon architecture combines >50% sp3 bonding, robust adhesion and self‐supporting performance, shielding substrates from plastic flow under extreme contact ...
Martin Zawischa   +3 more
wiley   +1 more source

fMRI and gene therapy in adults with CNGB3 mutation

open access: yesBrain Research Bulletin
Achromatopsia is an inherited retinal disease that affects 1 in 30,000–50,000 individuals and is characterised by an absence of functioning cone photoreceptors from birth.
Elaine J. Anderson   +6 more
doaj   +1 more source

Microfluidic Nano‐Assembly of Red‐Blood‐Cell (RBC) Lipids and Components for Engineering Extracellular Vesicles

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered red blood cell‐derived extracellular vesicles (eRBCEVs) are synthesized via controlled microfluidic assembly from native RBC lipids, enabling tunable encapsulation of proteins, nucleic acids, nanoparticles, and viral vectors. The platform demonstrates reproducible nanoscale architecture, preserved membrane composition, and functional cargo ...
Chiranth K. Nagaraj   +23 more
wiley   +1 more source

The role of retinol dehydrogenase 10 in the cone visual cycle

open access: yesScientific Reports, 2017
Pigment regeneration is critical for the function of cone photoreceptors in bright and rapidly-changing light conditions. This process is facilitated by the recently-characterized retina visual cycle, in which Müller cells recycle spent all-trans-retinol
Yunlu Xue   +11 more
doaj   +1 more source

Engineering Concentration‐Dependent Intravitreal Mobility via Cyclic Arginine‐Enriched Nanocarrier Surface Modification: In Vivo Proof‐of‐Concept in a Porcine Large Animal Model

open access: yesAdvanced Healthcare Materials, EarlyView.
In this study, Hammer et al. highlight cyclic‐arginine surface engineering as a highly biocompatible, controllable, and concentration‐dependent regulator of intravitreal nanoparticle mobility in vivo in a translational large animal model. The cyclic arginine surface‐modification supports the development of next‐generation biomaterials for long‐acting ...
Maximilian Hammer   +12 more
wiley   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

open access: yesAdvanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari   +10 more
wiley   +1 more source

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