Results 101 to 110 of about 4,186,077 (394)

A review of visual impairment

, 2018
Visual impairment (VI), a global concern that is likely to escalate with prolonged life expectancies, has gained increasing attention in the realm of eye care.
Shivani Naipal, N. Rampersad
semanticscholar   +1 more source

Stroke survivors’ views and experiences on impact of visual impairment

Brain and Behavior, 2017
We sought to determine stroke survivors’ views on impact of stroke‐related visual impairment to quality of life.
F. Rowe
semanticscholar   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Retinal ganglion cells induce stem cell-derived neuroprotection via IL-12 to SCGF-β crosstalk

Stem Cell Research & Therapy
Background Stem cell-derived secreted factors could protect neurons in neurodegenerative disease or after injury. The exact neuroprotective components in the secretome remain challenging to discover.
Qing Xia, Kun-Che Chang, Yanan Sun, Michael Nahmou, Takahiko Noro, Yun Cheng, Xiangmei Kong, Xiaofen Mo, Jeffrey L. Goldberg, Suqian Wu   +9 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Theories of developmental dyslexia: Insights from a multiple case study of dyslexic adults [PDF]

, 2002
A multiple case study was conducted in order to assess three leading theories of developmental dyslexia: the phonological, the magnocellular (auditory and visual) and the cerebellar theories.
Castellote, Juan M., Dakin, Steven C., Day, Brian L., Frith, Uta, Ramus, Franck, Rosen, Stuart, White, Sarah   +6 more
core   +3 more sources

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Magnitude, temporal trends, and projections of the global prevalence of blindness and distance and near vision impairment: a systematic review and meta-analysis [PDF]

, 2017
Background: Global and regional prevalence estimates for blindness and vision impairment are important for the development of public health policies. We aimed to provide global estimates, trends, and projections of global blindness and vision impairment.
Aditi Das, Aditi Das, MD, Alain Bron, Alan Morse, Alan Robin, Alex Silvester, Alex Silvester, MD, Anu Mathew, April Ingram, Aries Arditi, Banu Bozkurt, Beatriz Munoz, Billy Hammond, Charlotte Joslin, David Friedman, David Musch, Donald Budenz, Dwight Stambolian, Feng Cai, Fernando Yaacov Pena, Flavio Hirai, George Lambrou, Gianni Virgili, Gretchen A Stevens, DSc, Gretchen Stevens, Gus Gazzard, Hans LIMBURG, Hans Limburg, PhD, Harry Quigley, Hua Gao, Hugh R Taylor, MD, Hugh Taylor, Iva Dekaris, Jaewan Choi, Jaime Tejedor, James Hejtmancik, James Tielsch, Jan van Meurs, Janet Leasher, Janet Leasher, OD, Janet Serle, Jennifer Lim, Jenny Deva, Jill Keeffe, Jill Keeffe, PhD, Jimmy Volmink, Jinan Saaddine, Joao Furtado, John H Kempen, MD, John Huang, John Kempen, Jonathan Javitt, Jost B Jonas, MD, Jost Jonas, Juan Carlos Silva, Judy Kim, Kaweh Mansouri, Kevin Frick, Konrad Pesudovs, Konrad Pesudovs, PhD, Kovin Naidoo, Kovin Naidoo, PhD, Lalit Dandona, Laura Dreer, Leon Ellwein, Luca Rossetti, Marcela Frazier, MARIA PALAIOU, Maria V Cicinelli, MD, Maria Vittoria Cicinelli, Mary Elizabeth Hartnett, Maurizio Battaglia Parodi, Miltiadis Tsilimbaris, Minguang He, Moncef Khairallah, Monte Del Monte, Murugesan Raju, MYA SANDAR, Nathan Congdon, Nina Tahhan, PhD, Ning-Li Wang, Pamela Sieving, Paolo Lanzetta, Peter Ackland, Peter Wiedemann, Pradeep Ramulu, Prof Rupert R A Bourne, MD, Rajesh Shetty, Rakhi Dandona, Reza Dana, Richard Wormald, Rita S Sitorus, Robert Casson, Rohit Khanna, Rohit Varma, Ronnie George, Rupert Bourne, Serge Resnikoff, Serge Resnikoff, MD, Seth R Flaxman, BA, Sheila West, Stephen Gichuhi, TASANEE BRAITHWAITE, Tasanee Braithwaite, MPH, Tien Wong, Tien Y Wong, PhD, Tueng Shen, Tunde Peto, Usha Chakravarthy, Van Charles Lansingh, Victor Gonzalez, Vinay Nangia, Ya Xing Wang, Yaniv Barkana, Yingfeng Zheng   +114 more
core   +10 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Use of the Neurological Pupil Index to Predict Postoperative Visual Function After Resection of a Tuberculum Sellae Meningioma: A Case Report. [PDF]

, 2019
The Neurological Pupil index (NPi) is a standardized method for evaluating pupil reactivity that removes inter-examiner variability. Changes in the NPi can predict clinical deterioration in patients with traumatic brain injury (TBI); however, its use to ...
Raygor, Kunal P, Theodosopoulos, Philip V   +1 more
core   +1 more source